DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GC1 and slc25a22b

DIOPT Version :9

Sequence 1:	NP_001262490.1	Gene:	GC1 / 41448	FlyBaseID:	FBgn0260743	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	XP_009301224.1	Gene:	slc25a22b / 100005520	ZFINID:	ZDB-GENE-110408-66	Length:	318	Species:	Danio rerio

Alignment Length:	312	Identity:	185/312 - (59%)
Similarity:	228/312 - (73%)	Gaps:	19/312 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 QFALLPKIINGGIAGIIGVTCVFPLDLVKTRLQNQQIGPNGERMYNSMFDCFRKTYKAEGYFGMY 82
            |.:|..|:|||||||:||||||||:||.||||||||   ||.|:|.:|.||..||.::||:.|||
Zfish     5 QISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQ---NGSRVYTNMSDCLMKTVRSEGFTGMY 66

  Fly    83 RGSGVNILLITPEKAIKLTANDYFRHKLTTKDG-KLPLTSQMVAGGLAGAFQIIVTTPMELLKIQ 146
            ||:.||:.|:||||||||.|||:||.:| :||| ||.|..:|:||..||..|:|:|||||:||||
Zfish    67 RGAAVNLALVTPEKAIKLVANDFFRQQL-SKDGEKLTLVREMLAGCGAGTCQVIITTPMEMLKIQ 130

  Fly   147 MQDAGRVAAAAKLAG----------KTV--EKVSATQLASQLIKDKGIFGLYKGIGATGLRDVTF 199
            :|||||:.|..|:.|          :||  :..||.||:..|:|.|||.|||.|:|||.||||.|
Zfish   131 LQDAGRLEAQRKMIGPDAVRGRAKDRTVHLKSPSALQLSRNLLKHKGIAGLYTGLGATLLRDVPF 195

  Fly   200 SIIYFPLFATLNDLGPRRNDGSGEAVFWCSFLAGLAAGSTAALAVNPFDVVKTRLQAIKKADGEK 264
            |||||||||.||.||.|..|||  |.|:.|||:|..||..||:||||.||:|||||::.:...|.
Zfish   196 SIIYFPLFANLNSLGRRNADGS--APFYISFLSGCFAGCAAAVAVNPVDVIKTRLQSLSRGHHED 258

  Fly   265 EFKGISDCITKTLKHEGPTAFFKGGLCRMIVIAPLFGIAQTVYYLGVAEGLL 316
            .:.|:.|||:|.|:||||:||.||..||.:||||||||.|.||:|||.|.:|
Zfish   259 TYSGVRDCISKILRHEGPSAFLKGSYCRALVIAPLFGIVQVVYFLGVGEFVL 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GC1	NP_001262490.1	Mito_carr	36..113	CDD:278578	49/76 (64%)
		Mito_carr	115..213	CDD:278578	62/110 (56%)
		Mito_carr	226..307	CDD:278578	46/80 (58%)
slc25a22b	XP_009301224.1	PTZ00169	3..284	CDD:240302	167/284 (59%)
		Mito_carr	4..98	CDD:278578	62/96 (65%)
		Mito_carr	99..203	CDD:278578	56/103 (54%)
		Mito_carr	216..315	CDD:278578	56/97 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	108	1.000	Domainoid score	I6357
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	351	1.000	Inparanoid score	I2237
OMA	1	1.010	-	-		QHG53612
OrthoDB	1	1.010	-	-		D458796at33208
OrthoFinder	1	1.000	-	-		FOG0002230
OrthoInspector	1	1.000	-	-		mtm6363
orthoMCL	1	0.900	-	-		OOG6_104895
Panther	1	1.100	-	-	O	PTHR45678
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4126
SonicParanoid	1	1.000	-	-		X982
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	12.010