Protein Alignment aurA and IPL1

DIOPT Version :10

• Sequence 1: NP_476749.1
• Gene: aurA / 41446
• FlyBaseID: FBgn0000147
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_015115.1
• Gene: IPL1 / 855892
• SGDID: S000006130
• Length: 367
• Species: Saccharomyces cerevisiae
• Alignment Length: 388
• Identity: 148/388 - (38%)
• Similarity: 229/388 - (59%)
• Gaps: 41/388 - (10%)

  Fly    29 MQKNLLLGKKPNSENMAPASKPLPGSSGALIRKPGLGGSNSIASSEGNNFQKPMVPSVKKTTSEF 93
            ||:|.|:..|.|:.  :|:.|.....:.:.|.||.     .|:.|          |..:...|:.
Yeast     1 MQRNSLVNIKLNAN--SPSKKTTTRPNTSRINKPW-----RISHS----------PQQRNPNSKI 48

  Fly    94 AAPAPV------APIKKPESLSKQKPTAASSESSKELGAASSSAEKEKTKTETQPQKPK-KTWEL 151
              |:||      .|:...:.|..:     ||:....:..|:||....:.|     :.|| |:..|
Yeast    49 --PSPVREKLNRLPVNNKKFLDME-----SSKIPSPIRKATSSKMIHENK-----KLPKFKSLSL 101

  Fly   152 NNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQIGESNVEHQVRREIEIQSHLRHPHILR 216
            ::|::|:.||:||||.||..|.:.:.::.||||:.|.:|.:.|::.|.|||:|||:.|.||::.:
Yeast   102 DDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTK 166

  Fly   217 LYAYFHDDVRIYLILEYAPQGTLFNALQAQ-PMKRFDERQSATYIQALCSALLYLHERDIIHRDI 280
            .|.||||:.|:||::||...|.::..|:.. |   |::..::.||..:.:||.|:|:::||||||
Yeast   167 SYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGP---FNDILASDYIYQIANALDYMHKKNIIHRDI 228

  Fly   281 KPENLLLGHKGVLKIADFGWS-VHEPNSMRMTLCGTVDYLPPEMVQGKPHTKNVDLWSLGVLCFE 344
            ||||:|:|...|:|:.||||| ::.|.:.|.|:|||:|||.||||:.:.:...:|.|:||||.||
Yeast   229 KPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFE 293

  Fly   345 LLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAASHLISKLLVLNPQHRLPLDQVMVHPWIL 407
            ||.|..||..:..|.|||:|..:|.|:|.:||:.|..||.|||..:|:.|:.|..|.:|||||
Yeast   294 LLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKLLKYDPKDRMRLGDVKMHPWIL 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurA	NP_476749.1	STKc_Aurora	153..407	CDD:270909	116/255 (45%)
IPL1	NP_015115.1	STKc_Aurora	118..356	CDD:270909	108/240 (45%)