DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment aurA and AUR2

DIOPT Version :9

Sequence 1:	NP_476749.1	Gene:	aurA / 41446	FlyBaseID:	FBgn0000147	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001325078.1	Gene:	AUR2 / 817129	AraportID:	AT2G25880	Length:	349	Species:	Arabidopsis thaliana

Alignment Length:	293	Identity:	163/293 - (55%)
Similarity:	211/293 - (72%)	Gaps:	11/293 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 SKELGAASSSAEKEKTKTETQ----PQKPKKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVVA 181
            |:.||  ||:.......||||    .:..:|.|..::||||:.|||||||:|||||||.|..:||
plant    51 SRYLG--SSTISSMGISTETQQIAASEAAQKRWTTSDFDIGKPLGRGKFGHVYLAREKRSDHIVA 113

  Fly   182 LKVLFKRQIGESNVEHQVRREIEIQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQ 246
            ||||||.|:.:|.||||:|||:|||||||||:|||||.||:|..|:|||||||.:|.|:..|  |
plant   114 LKVLFKAQLQQSQVEHQLRREVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAVRGELYKEL--Q 176

  Fly   247 PMKRFDERQSATYIQALCSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWSVHEPNSMRMT 311
            ..|.|.||::|||:.:|..||:|.|.:.:|||||||||||:|.:|.|||||||||||..| .|.|
plant   177 KCKYFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHTFN-RRRT 240

  Fly   312 LCGTVDYLPPEMVQGKPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEH-- 374
            :|||:||||||||:...|..:||:||||:||:|.|.|..||.::.:.||||:|::||.|.|..
plant   241 MCGTLDYLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEAREHSETYKRIVQVDLKFPPKPI 305

  Fly   375 ISKAASHLISKLLVLNPQHRLPLDQVMVHPWIL 407
            :|.:|..|||::||.....||.|.:::.||||:
plant   306 VSSSAKDLISQMLVKESTQRLALHKLLEHPWIV 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aurA	NP_476749.1	STKc_Aurora	153..407	CDD:270909	151/255 (59%)
aurA	NP_476749.1	S_TKc	154..406	CDD:214567	150/253 (59%)
AUR2	NP_001325078.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	305	1.000	Domainoid score	I325
eggNOG	1	0.900	-	-		E1_KOG0580
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2670
Inparanoid	1	1.050	321	1.000	Inparanoid score	I705
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D954262at2759
OrthoFinder	1	1.000	-	-		FOG0000946
OrthoInspector	1	1.000	-	-		otm3008
orthoMCL	1	0.900	-	-		OOG6_100573
Panther	1	1.100	-	-	O	PTHR24350
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X555
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.870