| Sequence 1: | NP_476749.1 | Gene: | aurA / 41446 | FlyBaseID: | FBgn0000147 | Length: | 411 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_003152.1 | Gene: | RPS6KB1 / 6198 | HGNCID: | 10436 | Length: | 525 | Species: | Homo sapiens |
| Alignment Length: | 348 | Identity: | 110/348 - (31%) |
|---|---|---|---|
| Similarity: | 175/348 - (50%) | Gaps: | 46/348 - (13%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 96 PAPVAPIKKPESLS------KQKPTAASSESSKELGAASSSA-------------------EKEK 135
Fly 136 TKTETQPQKPKKTWELNNFDIGRLLGRGKFGNVYLARE---KESQFVVALKVLFKRQI--GESNV 195
Fly 196 EHQVRREIEIQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYI 260
Fly 261 QALCSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGW---SVHEPNSMRMTLCGTVDYLPPE 322
Fly 323 MVQGKPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAASHLISKLL 387
Fly 388 VLNPQHRL---PLD--QVMVHPW 405 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| aurA | NP_476749.1 | STKc_Aurora | 153..407 | CDD:270909 | 96/266 (36%) |
| RPS6KB1 | NP_003152.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..54 | 10/41 (24%) | |
| TOS motif | 28..32 | 0/3 (0%) | |||
| STKc_p70S6K | 94..416 | CDD:270736 | 95/262 (36%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 380..399 | ||||
| Autoinhibitory domain | 424..525 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||