Protein Alignment aurA and PRKCB

DIOPT Version :10

• Sequence 1: NP_476749.1
• Gene: aurA / 41446
• FlyBaseID: FBgn0000147
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_002729.2
• Gene: PRKCB / 5579
• HGNCID: 9395
• Length: 673
• Species: Homo sapiens
• Alignment Length: 333
• Identity: 93/333 - (27%)
• Similarity: 162/333 - (48%)
• Gaps: 33/333 - (9%)

  Fly    70 IASSEGNNFQKPMVPSVKKTTSEFAAPAPVAPIKKPESLSKQKPTAASSESSKELGAASSSAEKE 134
            ::..||..|..|:.|...:...|.......|.|.:...:.::|.|...|:       ..::..::
Human   278 LSQEEGEYFNVPVPPEGSEANEELRQKFERAKISQGTKVPEEKTTNTVSK-------FDNNGNRD 335

  Fly   135 KTKTETQPQKPKKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKR-QIGESNVEHQ 198
            :.|             |.:|:...:||:|.||.|.|:..|.:..:.|:|:|.|. .|.:.:||..
Human   336 RMK-------------LTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECT 387

  Fly   199 VRREIEIQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYIQAL 263
            :..:..:....:.|.:.:|::.|....|:|.::||...|.|.  ...|.:.||.|..:..|...:
Human   388 MVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLM--YHIQQVGRFKEPHAVFYAAEI 450

  Fly   264 CSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFG------WSVHEPNSMRMTLCGTVDYLPPE 322
            ...|.:|..:.||:||:|.:|::|..:|.:||||||      |.    .....|.|||.||:.||
Human   451 AIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWD----GVTTKTFCGTPDYIAPE 511

  Fly   323 MVQGKPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAASHLISKLL 387
            ::..:|:.|:||.|:.|||.:|:|.|.|||..::.||.::.|::.:...|:.:||.|..:...|:
Human   512 IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLM 576

  Fly   388 VLNPQHRL 395
            ..:|..||
Human   577 TKHPGKRL 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurA	NP_476749.1	STKc_Aurora	153..407	CDD:270909	80/250 (32%)
PRKCB	NP_002729.2	C1_cPKC_rpt1	35..92	CDD:410383
		C1_cPKC_rpt2	102..155	CDD:410386
		C2_PKC_alpha_gamma	159..289	CDD:175992	3/10 (30%)
		STKc_cPKC_beta	341..663	CDD:270767	80/250 (32%)