Protein Alignment aurA and PRKACG

DIOPT Version :10

• Sequence 1: NP_476749.1
• Gene: aurA / 41446
• FlyBaseID: FBgn0000147
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_002723.2
• Gene: PRKACG / 5568
• HGNCID: 9382
• Length: 351
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 94/266 - (35%)
• Similarity: 146/266 - (54%)
• Gaps: 10/266 - (3%)

  Fly   146 KKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQIGE-SNVEHQVRREIEIQSHL 209
            :.|...:.|:..|.||.|.||.|.|.|.:|:....|:|:|.|:::.: ..||| :..|..|...:
Human    36 QNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEH-ILNEKRILQAI 99

  Fly   210 RHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYIQALCSALLYLHERD 274
            ..|.:::|...|.|:..:||::||.|.|.:|:.||.  :.||.|..:..|...:..|:.|||..|
Human   100 DFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQR--VGRFSEPHACFYAAQVVLAVQYLHSLD 162

  Fly   275 IIHRDIKPENLLLGHKGVLKIADFGWSVHEPNSMRMTLCGTVDYLPPEMVQGKPHTKNVDLWSLG 339
            :||||:||||||:..:|.|::.|||:: ........|||||.:||.||::..|.:.|.||.|:||
Human   163 LIHRDLKPENLLIDQQGYLQVTDFGFA-KRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALG 226

  Fly   340 VLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAASHLISKLLVLNPQHRL-----PLDQ 399
            ||.:|:.||..|||:....:.|:||:....:.|..:|....||:..||.::...|.     .:..
Human   227 VLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGD 291

  Fly   400 VMVHPW 405
            :..|.|
Human   292 IKNHKW 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurA	NP_476749.1	STKc_Aurora	153..407	CDD:270909	93/259 (36%)
PRKACG	NP_002723.2	STKc_PKA	42..331	CDD:271111	93/260 (36%)