Protein Alignment aurA and aurkb

DIOPT Version :10

• Sequence 1: NP_476749.1
• Gene: aurA / 41446
• FlyBaseID: FBgn0000147
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: XP_012809281.1
• Gene: aurkb / 549613
• XenbaseID: XB-GENE-1019626
• Length: 370
• Species: Xenopus tropicalis
• Alignment Length: 341
• Identity: 177/341 - (51%)
• Similarity: 234/341 - (68%)
• Gaps: 28/341 - (8%)

  Fly    92 EFAAPAPVAPI-----KKP----------------ESLSKQKPTAASSESSKELGAASSSAEKEK 135
            |||.|:.....     |:|                ..|::..|:|:||...:.  |.|..|..:.
 Frog    25 EFATPSSATAAQRVLRKEPYVSTFTTPSDNLLAQRAQLARITPSASSSVPGRV--AVSMDASSQN 87

  Fly   136 TKTETQPQKPKKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQIGESNVEHQVR 200
            |   ...:.||:.:.:::|||||.||:||||||||||:|:::|::|||||||.|:.:..||||:|
 Frog    88 T---ALAELPKRKFTIDDFDIGRPLGKGKFGNVYLARDKQNKFIMALKVLFKSQLEKEGVEHQLR 149

  Fly   201 REIEIQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYIQALCS 265
            ||||||||||||:|||:|.||||..||||:||:||:|.|:..||..  .||||::|||:::.|..
 Frog   150 REIEIQSHLRHPNILRMYNYFHDRKRIYLMLEFAPRGELYKELQKH--GRFDEQRSATFMEELAD 212

  Fly   266 ALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWSVHEPNSMRMTLCGTVDYLPPEMVQGKPHT 330
            ||.|.|||.:|||||||||||:|:||.|||||||||||.|:..|.|:|||:|||||||::||.|.
 Frog   213 ALQYCHERKVIHRDIKPENLLMGYKGELKIADFGWSVHAPSLRRRTMCGTLDYLPPEMIEGKTHD 277

  Fly   331 KNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAASHLISKLLVLNPQHRL 395
            :.||||..||||||.|||..||.|.::.||:::|:.||.|.|..:|..:..||||||..:|..||
 Frog   278 EKVDLWCAGVLCFEFLVGMPPFDSPSHTETHRRIVNVDLKFPPFLSDGSKDLISKLLRYHPPQRL 342

  Fly   396 PLDQVMVHPWILAHTQ 411
            ||..||.|||:.|:::
 Frog   343 PLKGVMEHPWVKANSR 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurA	NP_476749.1	STKc_Aurora	153..407	CDD:270909	159/253 (63%)
aurkb	XP_012809281.1	STKc_Aurora-B_like	96..365	CDD:271019	160/265 (60%)