Protein Alignment aurA and aurka

DIOPT Version :9

• Sequence 1: NP_476749.1
• Gene: aurA / 41446
• FlyBaseID: FBgn0000147
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_001016570.1
• Gene: aurka / 549324
• XenbaseID: XB-GENE-853082
• Length: 415
• Species: Xenopus tropicalis
• Alignment Length: 417
• Identity: 201/417 - (48%)
• Similarity: 265/417 - (63%)
• Gaps: 42/417 - (10%)

  Fly     4 PSD-HVLRPKENAPHRMPEKSAAVHNMQKNLLLGKKPNSENMAPASKPLPGSSGALIRKPGLGGS 67
            ||: .|..|....|.|:|.               .:|.|..:.|     ||:  |:..:..||.|
 Frog    10 PSNVKVFHPTMEGPKRIPV---------------TQPPSTQVRP-----PGT--AVSAQRILGPS 52

  Fly    68 N------SIASSEGNNFQKPMVPSVKKTTSEFAAPAPVAPIK------KPESLSKQKPTAASSES 120
            |      |.|.....:.|||::.:.|..|.     .|:.|:.      ||:..::.:....:|.|
 Frog    53 NVPQRVVSQAQKPVMSAQKPVMSTQKPMTQ-----GPLRPVTHGHQAGKPQGPNENRTPQQTSHS 112

  Fly   121 SKELGAASSSAEKEKTKTETQPQKPKKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVL 185
            |........|.::.||....:.:..||.|.|.:|:|||.||:|||||||||||:||:|::|||||
 Frog   113 STPNVEKKGSTDQGKTLAVPKEEGKKKQWCLEDFEIGRPLGKGKFGNVYLARERESKFILALKVL 177

  Fly   186 FKRQIGESNVEHQVRREIEIQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKR 250
            ||.|:.::.||||:|||:|||||||||:|||||.||||..|:||||:|||.|.||..|  |.:.|
 Frog   178 FKTQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDAARVYLILDYAPGGELFREL--QKVTR 240

  Fly   251 FDERQSATYIQALCSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWSVHEPNSMRMTLCGT 315
            |||::||.||:.|..||||.|.:::|||||||||||||..|.|||||||||||.|:|.|.|||||
 Frog   241 FDEQKSALYIKQLAEALLYCHSKNVIHRDIKPENLLLGANGELKIADFGWSVHAPSSRRTTLCGT 305

  Fly   316 VDYLPPEMVQGKPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAAS 380
            :|||||||::|:.|.:.||||||||||:|.|||..||.:..:.|||::|.||:::.|.::|:.|.
 Frog   306 LDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFETDTHQETYRRISKVEFQYPSYVSEGAR 370

  Fly   381 HLISKLLVLNPQHRLPLDQVMVHPWIL 407
            .|:||||..||.|||.|..|:.||||:
 Frog   371 DLVSKLLKHNPNHRLSLKGVLEHPWII 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurA	NP_476749.1	STKc_Aurora	153..407	CDD:270909	162/253 (64%)
		S_TKc	154..406	CDD:214567	161/251 (64%)
aurka	NP_001016570.1	STKc_Aurora-A	140..397	CDD:271018	164/258 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	343	1.000	Domainoid score	I1060
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2670
Inparanoid	1	1.050	369	1.000	Inparanoid score	I2089
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D318112at33208
OrthoFinder	1	1.000	-	-		FOG0000946
OrthoInspector	1	1.000	-	-		otm47874
Panther	1	1.100	-	-	O	PTHR24350
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2391
SonicParanoid	1	1.000	-	-		X555
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.100