Protein Alignment aurA and aurB

DIOPT Version :9

• Sequence 1: NP_476749.1
• Gene: aurA / 41446
• FlyBaseID: FBgn0000147
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_477336.1
• Gene: aurB / 34504
• FlyBaseID: FBgn0024227
• Length: 329
• Species: Drosophila melanogaster
• Alignment Length: 288
• Identity: 139/288 - (48%)
• Similarity: 182/288 - (63%)
• Gaps: 16/288 - (5%)

  Fly   137 KTETQPQKPKKT----------------WELNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVL 185
            |...:.|:|.|.                |...:|::|..|||||||.||||||:.|.::||:||:
  Fly    20 KVPEEHQEPIKNMCLKMMSHDAYGQPYDWSPRDFEMGAHLGRGKFGRVYLARERHSHYLVAMKVM 84

  Fly   186 FKRQIGESNVEHQVRREIEIQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKR 250
            ||.::.:..|:.||.|||||||.|:|||||||..:|||:.||||.||.|.:|.||..|:..|..|
  Fly    85 FKEELRKGCVQRQVLREIEIQSRLKHPHILRLLTWFHDESRIYLALEIASEGELFKHLRGAPNHR 149

  Fly   251 FDERQSATYIQALCSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWSVHEPNSMRMTLCGT 315
            |||.:||.|...:.:||.|.|..::||||:||||:||.....||:||||||.|.||:.|.|||||
  Fly   150 FDEPRSAKYTYQVANALNYCHLNNVIHRDLKPENILLTSTDDLKLADFGWSAHTPNNKRRTLCGT 214

  Fly   316 VDYLPPEMVQGKPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAAS 380
            :||||||||.|..:..:||.|.||:||:|.:||..||.|.:.:.||.||.:::...|.|:||...
  Fly   215 LDYLPPEMVDGNSYDDSVDQWCLGILCYEFVVGCPPFESNSTESTYSKIRRMEISYPSHLSKGCK 279

  Fly   381 HLISKLLVLNPQHRLPLDQVMVHPWILA 408
            .||..||....:.|:.|..||.|.|:.|
  Fly   280 ELIGGLLRKESKGRITLVDVMTHYWVKA 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurA	NP_476749.1	STKc_Aurora	153..407	CDD:270909	133/253 (53%)
		S_TKc	154..406	CDD:214567	132/251 (53%)
aurB	NP_477336.1	STKc_Aurora	52..306	CDD:270909	133/253 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	249	1.000	Domainoid score	I347
eggNOG	1	0.900	-	-		E1_KOG0580
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53505
OrthoDB	1	1.010	-	-		D318112at33208
OrthoFinder	1	1.000	-	-		FOG0000946
OrthoInspector	1	1.000	-	-		otm46627
orthoMCL	1	0.900	-	-		OOG6_100573
Panther	1	1.100	-	-	P	PTHR24350
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2391
SonicParanoid	1	1.000	-	-		X555
	11	10.860