Protein Alignment aurA and Rps6ka5

DIOPT Version :10

• Sequence 1: NP_476749.1
• Gene: aurA / 41446
• FlyBaseID: FBgn0000147
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_001382521.1
• Gene: Rps6ka5 / 314384
• RGDID: 1308336
• Length: 798
• Species: Rattus norvegicus
• Alignment Length: 288
• Identity: 100/288 - (34%)
• Similarity: 156/288 - (54%)
• Gaps: 31/288 - (10%)

  Fly   123 ELGAASSSAEKEKTKTETQPQKPKKTWELNNFDIGRLLGRGKFGNVYLARE---KESQFVVALKV 184
            ||..|:.:...||...|             ||::.::||.|.:|.|:|.|:   .::..:.|:||
  Rat    30 ELRTANLTGHAEKVGIE-------------NFELLKVLGTGAYGKVFLVRKISGHDAGKLYAMKV 81

  Fly   185 LFKRQIGE--SNVEHQVRREIEIQSHLRH-PHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQ 246
            |.|..|.:  ...|| .|.|.::..|:|. |.::.|:..|..:.:::|||:|...|.||..|..:
  Rat    82 LKKATIVQKAKTTEH-TRTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQR 145

  Fly   247 PMKRFDERQSATYIQALCSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWS---VHEPNSM 308
              :||.|.:...|:..:..||.:||:..||:||||.||:||...|.:.:.|||.|   |.:....
  Rat   146 --ERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADEAER 208

  Fly   309 RMTLCGTVDYLPPEMVQG--KPHTKNVDLWSLGVLCFELLVGHAPFY---SKNYD-ETYKKILKV 367
            ..:.|||::|:.|::|:|  ..|.|.||.||||||.:|||.|.:||.   .||.. |..::|||.
  Rat   209 AYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKS 273

  Fly   368 DYKLPEHISKAASHLISKLLVLNPQHRL 395
            :...|:.:|..|..|:.:||:.:|:.||
  Rat   274 EPPYPQGMSSVAKDLLQRLLMKDPKKRL 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurA	NP_476749.1	STKc_Aurora	153..407	CDD:270909	94/258 (36%)
Rps6ka5	NP_001382521.1	Protein Kinases, catalytic domain	47..379	CDD:473864	94/258 (36%)
		STKc_MSK1_C	417..726	CDD:271081