Protein Alignment aurA and STK32C

DIOPT Version :10

• Sequence 1: NP_476749.1
• Gene: aurA / 41446
• FlyBaseID: FBgn0000147
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: XP_011537990.1
• Gene: STK32C / 282974
• HGNCID: 21332
• Length: 504
• Species: Homo sapiens
• Alignment Length: 373
• Identity: 107/373 - (28%)
• Similarity: 175/373 - (46%)
• Gaps: 41/373 - (10%)

  Fly    63 GLGGSNSIASSEGNNFQKPMVPSVKKTTSEFAAPAPVAPIKKPESLSKQKPTAASSESSKELGAA 127
            |.||..:..::.|...:|.::......:.......|:..:  |.|| ...|.|.|..|......|
Human     7 GAGGPGAGGAARGQPSRKELLLRHHLWSGPRCLSFPLGSL--PASL-LGLPGATSHRSCLSPNLA 68

  Fly   128 SSSAEKEKTKTETQP--------------QKPKKTWELNNFDIGRLLGRGKFG-----NVYLARE 173
            |..|.:   .|:||.              :..:|....::|.|.|.:|:|.||     .|.:.::
Human    69 SGLAAR---GTQTQSVLFGEVRLPLDGGVRGARKRMNFDHFQILRAIGKGSFGKPCALQVCIVQK 130

  Fly   174 KESQFVVALKVLFKRQIGESNVEHQVRREIEIQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGT 238
            ::::.:.|:|.:.|:|..|.:....|.||:||...:.|..::.|:..|.|:..::::::....|.
Human   131 RDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQEIEHVFLVNLWYSFQDEEDMFMVVDLLLGGD 195

  Fly   239 LFNALQAQPMKRFDERQSATYIQALCSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWSVH 303
            |...||..  .:|.|.....||..:..||.||..:.|||||:||:|:||..:|...:.||..:..
Human   196 LRYHLQQN--VQFSEDTVRLYICEMALALDYLRGQHIIHRDVKPDNILLDERGHAHLTDFNIATI 258

  Fly   304 EPNSMRMT-LCGTVDYLPPEMVQ-----GKPHTKNVDLWSLGVLCFELLVGHAPF--YSKNYDET 360
            ..:..|.| |.||..|:.||:..     |..::..||.||:||:.:|||.|..|:  :|.|..|:
Human   259 IKDGERATALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVGVMAYELLRGWRPYDIHSSNAVES 323

  Fly   361 YKKI---LKVDYKLPEHISKAASHLISKLLVLNPQHRL-PLDQVMVHP 404
            ..::   :.|.| :|.. ||....|:.|||.:||:||| .|..|...|
Human   324 LVQLFSTVSVQY-VPTW-SKEMVALLRKLLTVNPEHRLSSLQDVQAAP 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurA	NP_476749.1	STKc_Aurora	153..407	CDD:270909	87/269 (32%)
STK32C	XP_011537990.1	STKc_Yank1	105..371	CDD:270730	87/269 (32%)