Protein Alignment aurA and Prkaca

DIOPT Version :10

• Sequence 1: NP_476749.1
• Gene: aurA / 41446
• FlyBaseID: FBgn0000147
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_001094392.1
• Gene: Prkaca / 25636
• RGDID: 3389
• Length: 351
• Species: Rattus norvegicus
• Alignment Length: 296
• Identity: 95/296 - (32%)
• Similarity: 161/296 - (54%)
• Gaps: 15/296 - (5%)

  Fly   116 ASSESSKELGAASSSAEKEKTKTETQPQKPKKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVV 180
            :..||.||..|.:.....:|.:|.:|     .|.:|::||..:.||.|.||.|.|.:.|||....
  Rat    11 SEQESVKEFLAKAKEDFLKKWETPSQ-----NTAQLDHFDRIKTLGTGSFGRVMLVKHKESGNHY 70

  Fly   181 ALKVLFKRQIGE-SNVEHQVRREIEIQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQ 244
            |:|:|.|:::.: ..:||.:..:..:|: :..|.:::|...|.|:..:|:::||.|.|.:|:.|:
  Rat    71 AMKILDKQKVVKLKQIEHTLNEKRILQA-VNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLR 134

  Fly   245 AQPMKRFDERQSATYIQALCSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWSVHEPNSMR 309
            .  :.||.|..:..|...:.....|||..|:|:||:||||||:..:|.:::.|||:: .......
  Rat   135 R--IGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA-KRVKGRT 196

  Fly   310 MTLCGTVDYLPPEMVQGKPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEH 374
            .|||||.:||.||::..|.:.|.||.|:||||.:|:..|:.||::....:.|:||:....:.|.|
  Rat   197 WTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSH 261

  Fly   375 ISKAASHLISKLLVLNPQHRL-----PLDQVMVHPW 405
            .|.....|:..||.::...|.     .::.:..|.|
  Rat   262 FSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKW 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurA	NP_476749.1	STKc_Aurora	153..407	CDD:270909	85/259 (33%)
Prkaca	NP_001094392.1	STKc_PKA	42..331	CDD:271111	85/260 (33%)