Protein Alignment aurA and Aurkc

DIOPT Version :10

• Sequence 1: NP_476749.1
• Gene: aurA / 41446
• FlyBaseID: FBgn0000147
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_065597.2
• Gene: Aurkc / 20871
• MGIID: 1321119
• Length: 276
• Species: Mus musculus
• Alignment Length: 266
• Identity: 155/266 - (58%)
• Similarity: 200/266 - (75%)
• Gaps: 2/266 - (0%)

  Fly   146 KKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQIGESNVEHQVRREIEIQSHLR 210
            :|.:.:|:|:|||.|||||||.|||||.||:.|:||||||||.:|.:..:|||:|||:|||:||:
Mouse     8 RKHFTINDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQ 72

  Fly   211 HPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYIQALCSALLYLHERDI 275
            |.:|||||.||:||.||||||||||.|.|:..||..  ::.|::::||.||.|..||.|.||:.:
Mouse    73 HRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRH--QKLDQQRTATIIQELSDALTYCHEKKV 135

  Fly   276 IHRDIKPENLLLGHKGVLKIADFGWSVHEPNSMRMTLCGTVDYLPPEMVQGKPHTKNVDLWSLGV 340
            |||||||||||||..|.:||:|||||||.|:..|.|:|||:|||||||:..||:.:.||||.:||
Mouse   136 IHRDIKPENLLLGLNGEVKISDFGWSVHTPSLRRKTMCGTLDYLPPEMIAQKPYNEMVDLWCIGV 200

  Fly   341 LCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAASHLISKLLVLNPQHRLPLDQVMVHPW 405
            ||:|||||..||.|....|||::|.:||:|.|..:...|..||||||..:|..||.|.||:.|||
Mouse   201 LCYELLVGKPPFESSTSSETYRRIRQVDFKFPSSVPAGAQDLISKLLRYHPSERLSLAQVLKHPW 265

  Fly   406 ILAHTQ 411
            :..|::
Mouse   266 VREHSR 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurA	NP_476749.1	STKc_Aurora	153..407	CDD:270909	152/253 (60%)
Aurkc	NP_065597.2	Protein Kinases, catalytic domain	9..275	CDD:473864	155/265 (58%)