Protein Alignment aurA and Prkaca

DIOPT Version :10

• Sequence 1: NP_476749.1
• Gene: aurA / 41446
• FlyBaseID: FBgn0000147
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_032880.1
• Gene: Prkaca / 18747
• MGIID: 97592
• Length: 351
• Species: Mus musculus
• Alignment Length: 296
• Identity: 94/296 - (31%)
• Similarity: 159/296 - (53%)
• Gaps: 15/296 - (5%)

  Fly   116 ASSESSKELGAASSSAEKEKTKTETQPQKPKKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVV 180
            :..||.||..|.:.....:|.:|.:|     .|.:|:.||..:.||.|.||.|.|.:.|||....
Mouse    11 SEQESVKEFLAKAKEDFLKKWETPSQ-----NTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHY 70

  Fly   181 ALKVLFKRQIGE-SNVEHQVRREIEIQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQ 244
            |:|:|.|:::.: ..:||.:..:..:|: :..|.:::|...|.|:..:|:::||...|.:|:.|:
Mouse    71 AMKILDKQKVVKLKQIEHTLNEKRILQA-VNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLR 134

  Fly   245 AQPMKRFDERQSATYIQALCSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWSVHEPNSMR 309
            .  :.||.|..:..|...:.....|||..|:|:||:||||||:..:|.:::.|||:: .......
Mouse   135 R--IGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA-KRVKGRT 196

  Fly   310 MTLCGTVDYLPPEMVQGKPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEH 374
            .|||||.:||.||::..|.:.|.||.|:||||.:|:..|:.||::....:.|:||:....:.|.|
Mouse   197 WTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSH 261

  Fly   375 ISKAASHLISKLLVLNPQHRL-----PLDQVMVHPW 405
            .|.....|:..||.::...|.     .::.:..|.|
Mouse   262 FSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKW 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurA	NP_476749.1	STKc_Aurora	153..407	CDD:270909	84/259 (32%)
Prkaca	NP_032880.1	STKc_PKA	42..331	CDD:271111	84/260 (32%)