Protein Alignment aurA and air-2

DIOPT Version :9

• Sequence 1: NP_476749.1
• Gene: aurA / 41446
• FlyBaseID: FBgn0000147
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_491714.1
• Gene: air-2 / 172268
• WormBaseID: WBGene00000099
• Length: 305
• Species: Caenorhabditis elegans
• Alignment Length: 275
• Identity: 147/275 - (53%)
• Similarity: 190/275 - (69%)
• Gaps: 6/275 - (2%)

  Fly   132 EKEKTKTETQPQKPKKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQIGESNVE 196
            |||...|   |||..| :.:|:|:|||.||:||||:|||||.|...|.||:|||||.|:....||
 Worm    12 EKETVNT---PQKGGK-FTINDFEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVE 72

  Fly   197 HQVRREIEIQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYIQ 261
            ||:.|||||||||.||:|::||.||.|..:|||:|||||.|.::..|...  |||.|..:|.|:.
 Worm    73 HQLEREIEIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVS--KRFSEPTAAKYMY 135

  Fly   262 ALCSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWSVHEPNSMRMTLCGTVDYLPPEMVQG 326
            .:..||.|.|.:::|||||||||||:|.:|.|||.|||||||.|::.|.|:|||:||||||||.|
 Worm   136 EIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVHAPSNKRQTMCGTMDYLPPEMVNG 200

  Fly   327 KPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAASHLISKLLVLNP 391
            ..|:..||||::||||:|.|||..||..::..:||..|....:..|:.:.|.|..||.:|||::|
 Worm   201 ADHSDAVDLWAIGVLCYEFLVGKPPFEHEDQSKTYAAIKAARFTYPDSVKKGARDLIGRLLVVDP 265

  Fly   392 QHRLPLDQVMVHPWI 406
            :.|..|:||..|.||
 Worm   266 KARCTLEQVKEHYWI 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurA	NP_476749.1	STKc_Aurora	153..407	CDD:270909	138/254 (54%)
		S_TKc	154..406	CDD:214567	136/251 (54%)
air-2	NP_491714.1	STKc_Aurora	29..281	CDD:270909	138/254 (54%)
		S_TKc	30..280	CDD:214567	136/251 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0580
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2670
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S591
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D318112at33208
OrthoFinder	1	1.000	-	-		FOG0000946
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100573
Panther	1	1.100	-	-	O	PTHR24350
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2391
SonicParanoid	1	1.000	-	-		X555
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.800