Protein Alignment aurA and air-2

DIOPT Version :10

• Sequence 1: NP_476749.1
• Gene: aurA / 41446
• FlyBaseID: FBgn0000147
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_491714.1
• Gene: air-2 / 172268
• WormBaseID: WBGene00000099
• Length: 305
• Species: Caenorhabditis elegans
• Alignment Length: 275
• Identity: 147/275 - (53%)
• Similarity: 190/275 - (69%)
• Gaps: 6/275 - (2%)

  Fly   132 EKEKTKTETQPQKPKKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQIGESNVE 196
            |||...|   |||..| :.:|:|:|||.||:||||:|||||.|...|.||:|||||.|:....||
 Worm    12 EKETVNT---PQKGGK-FTINDFEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVE 72

  Fly   197 HQVRREIEIQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYIQ 261
            ||:.|||||||||.||:|::||.||.|..:|||:|||||.|.::..|...  |||.|..:|.|:.
 Worm    73 HQLEREIEIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVS--KRFSEPTAAKYMY 135

  Fly   262 ALCSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWSVHEPNSMRMTLCGTVDYLPPEMVQG 326
            .:..||.|.|.:::|||||||||||:|.:|.|||.|||||||.|::.|.|:|||:||||||||.|
 Worm   136 EIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVHAPSNKRQTMCGTMDYLPPEMVNG 200

  Fly   327 KPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAASHLISKLLVLNP 391
            ..|:..||||::||||:|.|||..||..::..:||..|....:..|:.:.|.|..||.:|||::|
 Worm   201 ADHSDAVDLWAIGVLCYEFLVGKPPFEHEDQSKTYAAIKAARFTYPDSVKKGARDLIGRLLVVDP 265

  Fly   392 QHRLPLDQVMVHPWI 406
            :.|..|:||..|.||
 Worm   266 KARCTLEQVKEHYWI 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurA	NP_476749.1	STKc_Aurora	153..407	CDD:270909	138/254 (54%)
air-2	NP_491714.1	STKc_Aurora	29..281	CDD:270909	138/254 (54%)