Protein Alignment CG3281 and ZNF343

DIOPT Version :10

• Sequence 1: NP_650132.1
• Gene: CG3281 / 41445
• FlyBaseID: FBgn0260741
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001269426.1
• Gene: ZNF343 / 79175
• HGNCID: 16017
• Length: 640
• Species: Homo sapiens
• Alignment Length: 341
• Identity: 74/341 - (21%)
• Similarity: 114/341 - (33%)
• Gaps: 144/341 - (42%)

  Fly  1669 VEIYLD-HEIIDEFV------IKIKDERHILPPVCLAGQKYSFDVNSDDKN--------KVRVTI 1718
            :|.|.: :|.:||.:      |||.|          .||.|..:..:|...        .:.||.
Human     4 IECYENSYESLDEDLDRDLSYIKIMD----------VGQSYVVNRVADHIQSRIVYYLMNIHVTP 58

  Fly  1719 R------------EPSGRMLPVQMEDLPDGGVRVSCRFKEVGIHSIDVFVDDQPIGERKMQTVID 1771
            |            ...||:         .|...:|.|.:|...| :..|:.||.|.:.|:.|
Human    59 RSIYLCRHGESELNLKGRI---------GGDPGLSPRGREFSKH-LAQFISDQNIKDLKVWT--- 110

  Fly  1772 PLNGAQLVSEPKREIVGEQT---------ELKIL--IDSGV-------ESQ----VEVIIEGPDR 1814
                    |:.||.|   ||         :.|:|  ||:||       |.|    :|..:...|:
Human   111 --------SQMKRTI---QTAEALSVPYEQWKVLNEIDAGVCEEMTYEEIQDHYPLEFALRDQDK 164

  Fly  1815 --------EDNEVFVKKVSETLWSAVWTPKVEGEHELSILV-----------------AGEQIPG 1854
                    |..|..|:::...:        :|.|.:.::||                 |.|::|.
Human   165 YRYRYPKGESYEDLVQRLEPVI--------MELERQENVLVICHQAVMRCLLAYFLDKAAEELPY 221

  Fly  1855 SPFPIHVLDPSAVRVIGLKNAPVG----VEQQFSVDYTNSGASIASVEVRHGDQTIPITVKKMKP 1915
            ...|:|.:         ||..||.    ||..|        .::|:|.. |.|:  |..|...:|
Human   222 LKCPLHTV---------LKLTPVAYGCKVESIF--------LNVAAVNT-HRDR--PQNVDISRP 266

  Fly  1916 GQLLCTFTPFVDGPHQ 1931
            .:......|    .||
Human   267 SEEALVTVP----AHQ 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3281	NP_650132.1	zf-AD	15..91	CDD:214871
		C2H2 Zn finger	205..226	CDD:275368
		C2H2 Zn finger	249..266	CDD:275368
		COG5048	<294..>391	CDD:227381
		C2H2 Zn finger	296..315	CDD:275368
		C2H2 Zn finger	323..343	CDD:275368
		C2H2 Zn finger	351..371	CDD:275368
		zf-H2C2_2	364..388	CDD:463886
		C2H2 Zn finger	379..399	CDD:275368
		zf-H2C2_2	391..416	CDD:463886
		C2H2 Zn finger	407..424	CDD:275368
ZNF343	NP_001269426.1	KRAB	61..102	CDD:460171	9/50 (18%)
		COG5048	307..>634	CDD:227381
		C2H2 Zn finger	312..332	CDD:275368
		C2H2 Zn finger	340..360	CDD:275368
		C2H2 Zn finger	368..388	CDD:275368
		C2H2 Zn finger	396..416	CDD:275368
		C2H2 Zn finger	424..444	CDD:275368
		C2H2 Zn finger	452..472	CDD:275368
		C2H2 Zn finger	480..500	CDD:275368
		C2H2 Zn finger	508..528	CDD:275368
		C2H2 Zn finger	536..556	CDD:275368
		C2H2 Zn finger	564..584	CDD:275368
		C2H2 Zn finger	592..612	CDD:275368
		C2H2 Zn finger	620..640	CDD:275368