Protein Alignment CG3281 and ZNF142

DIOPT Version :10

• Sequence 1: NP_650132.1
• Gene: CG3281 / 41445
• FlyBaseID: FBgn0260741
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001353219.1
• Gene: ZNF142 / 7701
• HGNCID: 12927
• Length: 1887
• Species: Homo sapiens
• Alignment Length: 549
• Identity: 112/549 - (20%)
• Similarity: 165/549 - (30%)
• Gaps: 178/549 - (32%)

  Fly     7 HVNISSQTCRVCLETHETN-------LYVHDEIKYNDLKLELWQLLEAVSKLKWTWTDPNLPMHL 64
            |..|....|..|.:|..||       |.|||:                            .|.|.
Human  1422 HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDK----------------------------TPTHF 1458

  Fly    65 CQNCARRLIGAYEFIVEVENAHE-TLQNLFEQQEVAAKPDEVHVDVVELIDQDDVVSMAQYLSTS 128
            |..|.......::....|.:.|: |......|.|                        ||:.|.:
Human  1459 CPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCE------------------------AQFSSET 1499

  Fly   129 FAEQHVEMEEKYGDQDCSAFTSDVGEEPLYASEDRDDEPEDSFQLKPRPDEIENRELSR------ 187
            ..:||.........|......::..|.||:.|.        ...|.|.|..:......:
Human  1500 ALKQHALRRHPEPAQPAPGSPAETTEGPLHCSR--------CGLLCPSPASLRGHTRKQHPRLEC 1556

  Fly   188 -------PSQLG----SRLNHSANFIYKCAVCPRVFAKSESLTRHFSQAHKLTADVAAMKLANES 241
                   ||:|.    .|..|   |.::|.:|.....:...|.:|:.:.|:.|:...|....:..
Human  1557 GACQEAFPSRLALDEHRRQQH---FSHRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGD 1618

  Fly   242 CGTGLLTCEHCPRTFKRQDTLRRHMQAFHPDAIALEPEETTDNSARKRIAKRRDCPHCGLSFPVS 306
            .|...|.|..|..|.:.|..|..
Human  1619 AGQPPLHCPFCDFTCRHQLVLDH------------------------------------------ 1641

  Fly   307 SLTIHIRRHTGDNPYKCDQCEKAFPRSQDLSLHMRQHTGERPSECKICSKKFISQNKLARHMRLH 371
                |::.|.|...|||..|..:....|.::.|.|.||||:|..|.:|.......::|..|||:|
Human  1642 ----HVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIH 1702

  Fly   372 TGQRPYSCKMCSKSFVQSNDLKIHMRRHTGERPYQCGVCGESFVCGSHLNIH---RNRKGH-LIA 432
            ..:|.|.|..|.......|.||.||.:|||.:||||..|.........|.:|   |:|:.. .:.
Human  1703 KEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMC 1767

  Fly   433 VIPGNEVEANFAADPYVNARVNQRRSEDIERMRLQRIPENQLQQRLENLPKPDVPAMCYKCGVCE 497
            ...|...:..|                 :.|..|::..|          .||      |.|.||.
Human  1768 EQCGKAFKTRF-----------------LLRTHLRKHSE----------AKP------YVCNVCH 1799

  Fly   498 QKFKSGALLTVHRNKMSHYEIERVYENPF 526
            :.|:..|       .:.|:.:.....:||
Human  1800 RAFRWAA-------GLRHHALTHTDRHPF 1821

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3281	NP_650132.1	zf-AD	15..91	CDD:214871	16/83 (19%)
		C2H2 Zn finger	205..226	CDD:275368	4/20 (20%)
		C2H2 Zn finger	249..266	CDD:275368	5/16 (31%)
		COG5048	<294..>391	CDD:227381	26/96 (27%)
		C2H2 Zn finger	296..315	CDD:275368	1/18 (6%)
		C2H2 Zn finger	323..343	CDD:275368	5/19 (26%)
		C2H2 Zn finger	351..371	CDD:275368	6/19 (32%)
		zf-H2C2_2	364..388	CDD:463886	9/23 (39%)
		C2H2 Zn finger	379..399	CDD:275368	7/19 (37%)
		zf-H2C2_2	391..416	CDD:463886	12/24 (50%)
		C2H2 Zn finger	407..424	CDD:275368	4/19 (21%)
ZNF142	NP_001353219.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23
		C2H2 Zn finger	365..385	CDD:275368
		C2H2 Zn finger	393..413	CDD:275368
		C2H2 Zn finger	421..438	CDD:275368
		C2H2 Zn finger	455..475	CDD:275368
		C2H2 Zn finger	545..566	CDD:275368
		C2H2 Zn finger	574..595	CDD:275368
		zf-H2C2_5	601..625	CDD:404746
		C2H2 Zn finger	603..623	CDD:275368
		C2H2 Zn finger	631..651	CDD:275368
		C2H2 Zn finger	659..679	CDD:275368
		C2H2 Zn finger	687..707	CDD:275368
		C2H2 Zn finger	714..731	CDD:275368
		PHA03247	928..>1219	CDD:223021
		C2H2 Zn finger	1306..1353	CDD:275368
		C2H2 Zn finger	1373..1394	CDD:275368
		C2H2 Zn finger	1402..1422	CDD:275368	112/549 (20%)
		C2H2 Zn finger	1430..1451	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1626..1646	CDD:275368	6/65 (9%)
		C2H2 Zn finger	1654..1674	CDD:275368	5/19 (26%)
		C2H2 Zn finger	1682..1702	CDD:275368	6/19 (32%)
		zf-H2C2_2	1694..1718	CDD:463886	9/23 (39%)
		C2H2 Zn finger	1710..1730	CDD:275368	7/19 (37%)
		zf-H2C2_2	1723..1747	CDD:463886	12/23 (52%)
		C2H2 Zn finger	1738..1759	CDD:275368	4/20 (20%)
		C2H2 Zn finger	1767..1787	CDD:275368	4/36 (11%)
		C2H2 Zn finger	1795..1815	CDD:275368	6/26 (23%)
		C2H2 Zn finger	1823..1843	CDD:275368