DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3281 and Zfp248

DIOPT Version :9

Sequence 1:NP_650132.1 Gene:CG3281 / 41445 FlyBaseID:FBgn0260741 Length:538 Species:Drosophila melanogaster
Sequence 2:NP_082611.1 Gene:Zfp248 / 72720 MGIID:1919970 Length:576 Species:Mus musculus


Alignment Length:506 Identity:135/506 - (26%)
Similarity:205/506 - (40%) Gaps:134/506 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    62 MHLCQNCARRLIGAYEFIVEVENAHETLQNLFEQQEVAAKP------DEVHVDVVELIDQD---D 117
            :.:|.:|...|......|:..:|......|.|   .:..||      :::.|. ::..|.|   |
Mouse   134 LKVCDSCEMNLKNVSAVIISKKNYSRKKLNEF---NIHKKPLPDSRREKIPVG-IKSCDYDGERD 194

  Fly   118 VVSMAQYLSTSFAEQHVEMEEK---YGDQD--CSAFTSDVGEEPLYASEDRDDEPEDSFQLKPRP 177
            .|.:.:.|:...:.|..|..|.   :.::.  |::..|.:| |.||...:......||.:|    
Mouse   195 GVRLCRDLARPVSHQPFEYNETGQGFCEEVALCTSQNSQLG-ETLYKHTECGRTFVDSLKL---- 254

  Fly   178 DEIENRELSRPSQLGSRLNHSANFIYKCAVCPRVF----------AKSESLTRHFSQAHKLTADV 232
                  .:|:.::|.:.|       ::|::|.:.|          |.|.|.....::..||..|.
Mouse   255 ------SVSQKTRLHTEL-------HECSICRKSFYVDLQFGHHTALSGSSPYERNEYEKLFCDG 306

  Fly   233 AAM---------------KLANESCGTGLLTCEHCPRTFKRQDTLRRHMQAFHPDAIAL--EPEE 280
            .|.               |::|.:.|.        |..||.|             .|.:  :|.|
Mouse   307 TAFIVHQEAYTRKIAQEYKVSNRTWGK--------PALFKHQ-------------IIQMGGKPYE 350

  Fly   281 TTDNSARKRIAKRR---------------DCPHCGLSF-PVSSLTIHIRRHTGDNPYKCDQCEKA 329
            ..:|  ||..:|:.               :|..||..| ..|:||.|.|.|||:.||:|.:|.||
Mouse   351 YYEN--RKNFSKKSHPTQPRRPHVGEKTFECGECGKMFWEKSNLTQHQRTHTGEKPYECTECGKA 413

  Fly   330 FPRSQDLSLHMRQHTGERPSECKICSKKFISQNKLARHMRLHTGQRPYSCKMCSKSFVQSNDLKI 394
            |.:...|:.|.|.||||:|.|||.|.|.|..::.|..|.|.|||::||.|..|.|||...:.|.:
Mouse   414 FCQKPHLTNHQRTHTGEKPYECKQCGKTFCVKSNLTEHQRTHTGEKPYECNACRKSFCHRSALTV 478

  Fly   395 HMRRHTGERPYQCGVCGESFVCGSHLNIH-RNRKGHLIAVIPGNEVEANFAADPYVNARVNQRRS 458
            |.|.||||:|:.|..||:||...|:|.:| |...|.                .||   :.|:...
Mouse   479 HQRTHTGEKPFICSECGKSFCVKSNLIVHQRTHTGE----------------KPY---KCNECGK 524

  Fly   459 EDIERMRLQRIPENQLQQRLENLPKPDVPAMCYKCGVCEQKFKSGALLTVH 509
            ...|:..|.:      .||.....||      |:|.||.:.|...::||.|
Mouse   525 TFCEKSALTK------HQRTHTGEKP------YECHVCGKTFSQRSVLTKH 563

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3281NP_650132.1 zf-AD 14..92 CDD:285071 5/29 (17%)
C2H2 Zn finger 205..226 CDD:275368 6/30 (20%)
C2H2 Zn finger 249..266 CDD:275368 4/16 (25%)
COG5048 <294..>391 CDD:227381 46/112 (41%)
C2H2 Zn finger 296..315 CDD:275368 9/19 (47%)
zf-H2C2_2 307..330 CDD:290200 12/22 (55%)
C2H2 Zn finger 323..343 CDD:275368 8/19 (42%)
zf-H2C2_2 335..358 CDD:290200 13/22 (59%)
C2H2 Zn finger 351..371 CDD:275368 8/19 (42%)
zf-H2C2_2 364..388 CDD:290200 13/23 (57%)
C2H2 Zn finger 379..399 CDD:275368 8/19 (42%)
zf-H2C2_2 391..416 CDD:290200 13/24 (54%)
C2H2 Zn finger 407..424 CDD:275368 8/17 (47%)
Zfp248NP_082611.1 KRAB 8..68 CDD:214630
C2H2 Zn finger 379..399 CDD:275368 9/19 (47%)
COG5048 403..>469 CDD:227381 31/65 (48%)
C2H2 Zn finger 407..427 CDD:275368 8/19 (42%)
C2H2 Zn finger 435..455 CDD:275368 8/19 (42%)
COG5048 459..>520 CDD:227381 27/79 (34%)
C2H2 Zn finger 463..483 CDD:275368 8/19 (42%)
C2H2 Zn finger 491..511 CDD:275368 9/19 (47%)
zf-H2C2_2 503..526 CDD:404364 7/41 (17%)
C2H2 Zn finger 519..539 CDD:275368 5/25 (20%)
zf-H2C2_2 531..556 CDD:404364 10/36 (28%)
C2H2 Zn finger 547..567 CDD:275368 7/17 (41%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167836684
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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