Protein Alignment CG3281 and ZFP69B

DIOPT Version :10

• Sequence 1: NP_650132.1
• Gene: CG3281 / 41445
• FlyBaseID: FBgn0260741
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_005271193.1
• Gene: ZFP69B / 65243
• HGNCID: 28053
• Length: 535
• Species: Homo sapiens
• Alignment Length: 386
• Identity: 110/386 - (28%)
• Similarity: 159/386 - (41%)
• Gaps: 88/386 - (22%)

  Fly   148 FTSDVGEEPLYASEDRDDEPEDSFQLKPRPDEIENRELSRPSQLGSR-------LNHSANF---- 201
            ||.:.|:|    |...:.......::.|.|..:..:...:....|.|       :|||.::
Human   218 FTQERGQE----SNRFEKRINVKSEVMPGPIGLPRKRDRKYDTPGKRSRYNIDLVNHSRSYTKMK 278

  Fly   202 IYKCAVCPRVFAKSESLTRHFSQAHKLTADVAAMKLANESCGTGLLTCEHCPRTFKRQDTLRRHM 266
            .::|.:|.::|.:...||.|             |::   ..|.....|:.|.:.|.:..:|..|
Human   279 TFECNICEKIFKQLIHLTEH-------------MRI---HTGEKPFRCKECGKAFSQSSSLIPH- 326

  Fly   267 QAFHPDAIALEPEETTDNSARKRIAKRRDCPHCGLSF--PVSSLTIHIRRHTGDNPYKCDQCEKA 329
            |..|..                  .|..:|..||.:|  | ||||.|:|.|||:.||:|..||||
Human   327 QRIHTG------------------EKPYECKECGKTFRHP-SSLTQHVRIHTGEKPYECRVCEKA 372

  Fly   330 FPRSQDLSLHMRQHTGERPSECKICSKKFISQNKLARHMRLHTGQRPYSCKMCSKSFVQSNDLKI 394
            |.:|..|..|:|.|..|:|..||.|.|.|.....|.:|..:|||.:||.|.:|||:|..|..|..
Human   373 FSQSIGLIQHLRTHVREKPFTCKDCGKAFFQIRHLRQHEIIHTGVKPYICNVCSKTFSHSTYLTQ 437

  Fly   395 HMRRHTGERPYQCGVCGESFVCGSHLNIHRNRKGHLIAVIPGNEVEANFAADPYVNARVNQRRSE 459
            |.|.|||||||:|..||::|....||:||:               ..:....||..:...:....
Human   438 HQRTHTGERPYKCKECGKAFSQRIHLSIHQ---------------RVHTGVKPYECSHCGKAFRH 487

  Fly   460 DIERMRLQRIPENQLQQRLENLPKPDVPAMCYKCGVCEQKFKSGALLTVH-----RNKMSH 515
            |....:.|||...:         ||      |.|..|.:.|...:.|..|     ||..|:
Human   488 DSSFAKHQRIHTGE---------KP------YDCNECGKAFSCSSSLIRHCKTHLRNTFSN 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3281	NP_650132.1	zf-AD	15..91	CDD:214871
		C2H2 Zn finger	205..226	CDD:275368	6/20 (30%)
		C2H2 Zn finger	249..266	CDD:275368	4/16 (25%)
		COG5048	<294..>391	CDD:227381	47/98 (48%)
		C2H2 Zn finger	296..315	CDD:275368	11/20 (55%)
		C2H2 Zn finger	323..343	CDD:275368	10/19 (53%)
		C2H2 Zn finger	351..371	CDD:275368	7/19 (37%)
		zf-H2C2_2	364..388	CDD:463886	12/23 (52%)
		C2H2 Zn finger	379..399	CDD:275368	9/19 (47%)
		zf-H2C2_2	391..416	CDD:463886	14/24 (58%)
		C2H2 Zn finger	407..424	CDD:275368	7/16 (44%)
ZFP69B	XP_005271193.1	SCAN	<2..40	CDD:460417
		KRAB	74..134	CDD:214630
		COG5048	<194..430	CDD:227381	73/251 (29%)
		C2H2 Zn finger	258..274	CDD:275368	5/15 (33%)
		C2H2 Zn finger	282..302	CDD:275368	7/35 (20%)
		C2H2 Zn finger	310..330	CDD:275368	6/20 (30%)
		C2H2 Zn finger	338..358	CDD:275368	11/20 (55%)
		C2H2 Zn finger	366..386	CDD:275368	10/19 (53%)
		C2H2 Zn finger	394..414	CDD:275368	7/19 (37%)
		C2H2 Zn finger	422..442	CDD:275368	9/19 (47%)
		zf-H2C2_2	434..459	CDD:463886	14/24 (58%)
		C2H2 Zn finger	450..470	CDD:275368	8/34 (24%)
		zf-H2C2_2	462..487	CDD:463886	6/39 (15%)
		C2H2 Zn finger	478..498	CDD:275368	3/19 (16%)
		zf-H2C2_2	490..515	CDD:463886	9/39 (23%)
		C2H2 Zn finger	506..526	CDD:275368	5/19 (26%)