DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3281 and KRBOX4

DIOPT Version :9

Sequence 1:	NP_650132.1	Gene:	CG3281 / 41445	FlyBaseID:	FBgn0260741	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_001123370.1	Gene:	KRBOX4 / 55634	HGNCID:	26007	Length:	171	Species:	Homo sapiens

Alignment Length:	141	Identity:	31/141 - (21%)
Similarity:	47/141 - (33%)	Gaps:	37/141 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LETHETNLYVHDEIKYNDLKLELWQLLEAVSKL-------------KWTW-TDPNLPMHLCQNCA 69
            |::.:.||       |.|:.||.:..|.:|..|             :.:| .|...|:..|
Human    25 LDSAQKNL-------YRDVMLENYSHLVSVGYLVAKPDVIFRLGPGEESWMADGGTPVRTC---- 78

  Fly    70 RRLIGAYEFIVEVENAHETLQNLFEQQ-----EVAAKPDEVHVDVVELIDQDDVVSMAQYLSTSF 129
                 |.|...||....|.:.:..|.|     :.|....|...|  |...:......:.||||.|
Human    79 -----AGEDRPEVWQVDEQIDHYKESQDKLPWQAAFIGKETLKD--ESGQESRTCRKSIYLSTEF 136

  Fly   130 AEQHVEMEEKY 140
            ......:.:.|
Human   137 DSVRQRLPKYY 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3281	NP_650132.1	zf-AD	14..92	CDD:285071	19/86 (22%)
		C2H2 Zn finger	205..226	CDD:275368
		C2H2 Zn finger	249..266	CDD:275368
		COG5048	<294..>391	CDD:227381
		C2H2 Zn finger	296..315	CDD:275368
		zf-H2C2_2	307..330	CDD:290200
		C2H2 Zn finger	323..343	CDD:275368
		zf-H2C2_2	335..358	CDD:290200
		C2H2 Zn finger	351..371	CDD:275368
		zf-H2C2_2	364..388	CDD:290200
		C2H2 Zn finger	379..399	CDD:275368
		zf-H2C2_2	391..416	CDD:290200
		C2H2 Zn finger	407..424	CDD:275368
KRBOX4	NP_001123370.1	KRAB	8..68	CDD:214630	10/49 (20%)
KRBOX4	NP_001123370.1	KRAB	8..47	CDD:279668	8/28 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146642
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930