DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3281 and az2

DIOPT Version :10

Sequence 1:NP_650132.1 Gene:CG3281 / 41445 FlyBaseID:FBgn0260741 Length:538 Species:Drosophila melanogaster
Sequence 2:NP_610289.2 Gene:az2 / 35682 FlyBaseID:FBgn0025185 Length:593 Species:Drosophila melanogaster


Alignment Length:416 Identity:98/416 - (23%)
Similarity:148/416 - (35%) Gaps:121/416 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 LYVHDEIKYNDLKLELWQLLEAVS-------KLKWTWTDPNLPMHLCQNCARRLIGAY-EFIVEV 82
            ||.|.  ||:.| .|...|.:|.|       |:|..:|:.|       ....:.|..| :|....
  Fly   233 LYYHG--KYSFL-AERGSLEDADSDDVDGDGKIKLVFTEEN-------QLTTQFIDLYSKFPQLY 287

  Fly    83 ENAHETLQNLFEQQEVAAKPDEV-----------HVDVVELIDQDDVVSMAQYLS------TSFA 130
            :.||:...||..::....:..::           |.||     .|.:.||.|:.|      |...
  Fly   288 DPAHKHFCNLNVRKSSLIEITDLLTSEFSLGLVTHYDV-----YDSIQSMRQWYSRRIKTLTDVQ 347

  Fly   131 EQHVEMEEKYGDQDCSAFTSDVGEEPLYASEDRDDEPEDSFQLKPRPDEIENRELSRPSQLGSRL 195
            ...:.:.||...:.|::|.                 |..||:.|                     
  Fly   348 CVGLSLAEKQYIERCNSFM-----------------PTKSFRQK--------------------- 374

  Fly   196 NHSANFIYKCAVCPRVFAKSESLTRHFSQAHKLTADVAAMKLANESCGTGLLTCEHCPRTFKRQD 260
                   .||.||...|:...:|..|..:.||:.             ..|...|..|...|.|:.
  Fly   375 -------LKCEVCEHSFSTDHALQAHQFRDHKMG-------------DGGWFRCTLCELNFDRKC 419

  Fly   261 TLRRHMQAFHPD----------------AIALEPEETTDNSARKRIAKRRDCPHCGLSFPVS-SL 308
            .|::|.|..|.|                .:|:. :.|.|   .|.:||...|..||..|... .:
  Fly   420 HLQQHSQRVHMDKSFVCEICSRSFAFGNQLAIH-KRTHD---EKHVAKPFVCEFCGKCFKQKIQM 480

  Fly   309 TIHIRR-HTGDNPYKCDQCEKAFPRSQDLSLHMRQHTGERPSECKICSKKFISQNKLARHMRLHT 372
            |.|:.. ||....:|||.|.|.|...:||..|::.|...|...|::|.|.|.:.|.|.:|..:|.
  Fly   481 TTHVTAVHTKIRAFKCDMCPKDFLTKRDLKDHVKAHLNIRDKVCEVCQKAFTNANALVKHRHIHK 545

  Fly   373 GQRPYSCKMCSKSFVQSNDLKIHMRR 398
             ::...|.:|:..|.:...|.:||||
  Fly   546 -EKTLQCSLCTTRFSERVSLGVHMRR 570

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3281NP_650132.1 zf-AD 15..91 CDD:214871 19/72 (26%)
C2H2 Zn finger 205..226 CDD:275368 6/20 (30%)
C2H2 Zn finger 249..266 CDD:275368 5/16 (31%)
COG5048 <294..>391 CDD:227381 30/98 (31%)
C2H2 Zn finger 296..315 CDD:275368 6/20 (30%)
C2H2 Zn finger 323..343 CDD:275368 8/19 (42%)
C2H2 Zn finger 351..371 CDD:275368 7/19 (37%)
zf-H2C2_2 364..388 CDD:463886 6/23 (26%)
C2H2 Zn finger 379..399 CDD:275368 8/20 (40%)
zf-H2C2_2 391..416 CDD:463886 5/8 (63%)
C2H2 Zn finger 407..424 CDD:275368
az2NP_610289.2 MADF_DNA_bdg 157..242 CDD:463144 5/10 (50%)
MADF_DNA_bdg 276..>341 CDD:463144 15/69 (22%)
C2H2 Zn finger 377..398 CDD:275368 6/20 (30%)
C2H2 Zn finger 408..429 CDD:275368 7/20 (35%)
C2H2 Zn finger 436..456 CDD:275368 1/20 (5%)
C2H2 Zn finger 467..488 CDD:275368 6/20 (30%)
C2H2 Zn finger 496..516 CDD:275368 8/19 (42%)
C2H2 Zn finger 524..544 CDD:275368 7/19 (37%)
C2H2 Zn finger 551..572 CDD:275368 8/20 (40%)
Blue background indicates that the domain is not in the aligned region.

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