DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3281 and Zbtb11

DIOPT Version :9

Sequence 1:	NP_650132.1	Gene:	CG3281 / 41445	FlyBaseID:	FBgn0260741	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	XP_038944302.1	Gene:	Zbtb11 / 304010	RGDID:	1308275	Length:	1092	Species:	Rattus norvegicus

Alignment Length:	712	Identity:	151/712 - (21%)
Similarity:	241/712 - (33%)	Gaps:	223/712 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 ISSQTCRVCL-------ETHETNLYVHDEIKYNDLKLELWQLL--EAVSKLKWTWTDPNLPM--- 62
            :|:|.|.|.|       :.|::.|..:.|. :.||.:|...:.  |||..|........||:
  Rat   209 LSNQFCDVTLLIEGEEYKAHKSVLSANSEY-FRDLFIEKGAVSSHEAVVDLSGFCKASFLPLLEF 272

  Fly    63 --------HLCQNCARRLIGAYEFIVEVENAHETLQNLFEQQEV--------------------- 98
                    ..|......::..:.|:.||....|::..|.|::::
  Rat   273 AYTSVLSFDFCSMADVAVLARHLFMSEVLEICESVHKLMEEKQLTVYKKGEVQTVASTQDLAAHN 337

  Fly    99 -AAKP-------------DEVHVDVVELI-----------------------DQDDVVSM----- 121
             ||.|             |..|.::|.|:                       :.:..||.
  Rat   338 GAATPPGPRNEATTTLSSDLGHCEIVLLVNGEVPETEQNGEPGQQPAPQVSAEAEASVSPAGCIP 402

  Fly   122 -------AQYLSTSFAEQHVEMEEKYGDQDCSAFTSDVGEEPLY--ASED----RDDEPEDSFQL 173
                   |..|:|...:..:|......|...::....:.||.:.  :.||    .|..|||:...
  Rat   403 NPPTEMGAASLATESNQPELESAVVREDGGVASVPPKISEENVINTSQEDSDIGNDTSPEDTCTK 467

  Fly   174 ----------KPRPDE---IENRELSRP--------SQLGSRLNHSANFIYKCAVCPRVFAKSES 217
                      :|..||   ||..|.:..        |:|..|..:...:|.......:...|.::
  Rat   468 DFSDHSQSSGQPLKDEETLIEATEKTDSGQDDDTYRSRLRQRSVNEGGYIRLHKGMEKKLQKRKA 532

  Fly   218 LTRHFSQ--AHKLTADVAAMKL----ANESCGTGLLTCEHCPRTFKRQDTLRRHMQAFHPDAIAL 276
            :::...|  |.||......||.    |.||.......|..|...|.|:.....|         .|
  Rat   533 ISKSAVQQVAQKLVQRGKKMKQPKRDAKESAEETPHKCGECGMVFPRRYAFIMH---------TL 588

  Fly   277 EPEETTDNSARKRIAKRRDCPHCGLSFPVS-SLTIHIRRHT-GDNP------------------- 320
            :.|...|..          ||.|...|..| ||..|:.||| .|.|
  Rat   589 KHERARDYK----------CPLCKKQFQYSASLRAHLIRHTRKDAPTSSSSNSTSNEASGASSEK 643

  Fly   321 ------YKCDQCEKAFPRSQDLSLHMRQHTGERPSECKICSKKFISQNKLARHMRLHTGQRPYSC 379
                  :.|..|.:..|:...|.:||.:|||.:|..|::|.|.||.::.|..|..||..|:.:.|
  Rat   644 GRTKREFICSICGRTLPKLYSLRIHMLKHTGVKPHACQVCGKTFIYKHGLKLHQSLHQSQKQFQC 708

  Fly   380 KMCSKSFVQSNDLKIHMRRHTGERPYQCGVCGESFVCGS----HLNIHRNR---KGH-------- 429
            ::|.||||....|:.||..||||..|.|.|||:||..||    ||..|:.:   :|:
  Rat   709 ELCVKSFVTKRSLQEHMSIHTGESKYFCSVCGKSFHRGSGLSKHLKKHQPKPEVRGYHCTQLHMD 773

  Fly   430 ---------------LIAVIPGNEVEANFAADPYVNARVNQRRSEDIERMRLQRIPENQLQ---- 475
                           |..|.||:..::......::....:...:.|:.:...:.:.....|
  Rat   774 QVWQCFQLLILSASKLSRVFPGSSCKSPVFPSDWIQCEKSFFEARDLRQHMNKHLGVKPFQCQFC 838

  Fly   476 -------------QRLENLPKPDVPAMCYKCGVCEQKFKSGALLTVHRNKMSHYEIERVYEN 524
                         .:..::.:|      |:|.:|.::|...||...|..|.:|.:..|..:|
  Rat   839 DKCYSWKKDWYSHVKSHSVTEP------YRCNICGKEFYEKALFRRHVKKATHGKKGRAKQN 894

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3281	NP_650132.1	zf-AD	14..92	CDD:285071	20/97 (21%)
		C2H2 Zn finger	205..226	CDD:275368	2/22 (9%)
		C2H2 Zn finger	249..266	CDD:275368	4/16 (25%)
		COG5048	<294..>391	CDD:227381	39/123 (32%)
		C2H2 Zn finger	296..315	CDD:275368	8/19 (42%)
		zf-H2C2_2	307..330	CDD:290200	10/48 (21%)
		C2H2 Zn finger	323..343	CDD:275368	6/19 (32%)
		zf-H2C2_2	335..358	CDD:290200	10/22 (45%)
		C2H2 Zn finger	351..371	CDD:275368	7/19 (37%)
		zf-H2C2_2	364..388	CDD:290200	10/23 (43%)
		C2H2 Zn finger	379..399	CDD:275368	9/19 (47%)
		zf-H2C2_2	391..416	CDD:290200	14/24 (58%)
		C2H2 Zn finger	407..424	CDD:275368	10/20 (50%)
Zbtb11	XP_038944302.1	Integrase_H2C2	68..120	CDD:407771
		BTB_POZ_ZBTB11	195..312	CDD:349511	23/103 (22%)
		PRK12387	<556..621	CDD:183492	22/83 (27%)
		C2H2 Zn finger	570..590	CDD:275368	6/28 (21%)
		C2H2 Zn finger	598..618	CDD:275368	8/19 (42%)
		C2H2 Zn finger	652..672	CDD:275368	6/19 (32%)
		zf-H2C2_2	664..689	CDD:404364	11/24 (46%)
		C2H2 Zn finger	680..700	CDD:275368	7/19 (37%)
		COG5048	695..>801	CDD:227381	34/105 (32%)
		C2H2 Zn finger	708..728	CDD:275368	9/19 (47%)
		C2H2 Zn finger	736..756	CDD:275368	10/19 (53%)
		C2H2 Zn finger	809..827	CDD:275368	1/17 (6%)
		zf-H2C2_2	819..843	CDD:404364	2/23 (9%)
		C2H2 Zn finger	835..855	CDD:275368	0/19 (0%)
		C2H2 Zn finger	863..885	CDD:275368	7/21 (33%)
		C2H2 Zn finger	899..919	CDD:275368
		C2H2 Zn finger	927..947	CDD:275368
		zf-H2C2_2	939..962	CDD:404364
		C2H2 Zn finger	955..976	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000