DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3281 and Zbtb41

DIOPT Version :9

Sequence 1:	NP_650132.1	Gene:	CG3281 / 41445	FlyBaseID:	FBgn0260741	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_001178599.1	Gene:	Zbtb41 / 289052	RGDID:	1560834	Length:	908	Species:	Rattus norvegicus

Alignment Length:	671	Identity:	145/671 - (21%)
Similarity:	244/671 - (36%)	Gaps:	188/671 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LETHETNLY------VHDEIKYNDLKLELWQLL--EAVSKLKWTWTDPNLP-------------M 62
            |.|.|..:|      |.:..|:.|: ::..:||  |.|:..:...||.:.|             .
  Rat   144 LYTSEFFVYKYEIPLVLEAAKFLDI-IDAVKLLNNENVATFQAELTDKSSPEETLNELTGRLSNN 207

  Fly    63 HLCQNCARR------------------LIGAYEFIVEVENAHETLQNLFEQQEVAAKPDEVHVDV 109
            |.|:.|:|.                  |:|....:..:|.:..|.::. ..::...|.|:...|.
  Rat   208 HQCKFCSRHFCYKKSLENHLAKTHRSLLLGKKHGLKMLERSFSTRRSK-RNRKCPVKFDDTSDDE 271

  Fly   110 VELIDQDDVVSMAQY------------LSTSFAEQHVEMEEKYGDQDCSAFTS----DVGEEPLY 158
            .|..|..|.::...:            ..:.:..:..|:||:..|::.....|    |..|||..
  Rat   272 QESGDGSDNLNQESFDKERSDRNDSEDPGSDYNVEDEELEEEVSDEESDTEQSDKDNDAEEEPEA 336

  Fly   159 ASE------------------------------DRDDEPEDSFQL----KPRPDEIENRELSRPS 189
            |..                              ||..:.|...::    ||...:|.::..|..|
  Rat   337 ADSAGSIHEGLAPVVIQNSNKKILQCPKCDKTFDRIGKYESHTRVHTGEKPFECDICHQRYSTKS 401

  Fly   190 QLG-SRLNHSANFIY-----KCAVCPRVFAKSESLTRHFSQAHKLTAD--VAAMKLANESCGTGL 246
            .|. .|..||:...:     ||..|.::.|..::|.:|..:.|...|.  ::..|..:||
  Rat   402 NLTVHRKKHSSEVEFHKKEHKCPYCNKLHASKKTLAKHVKRFHPENAQEFISIKKTKSES----- 461

  Fly   247 LTCEHCPRTFKRQDTLRRHMQAFHPDAIALEPEETT--DNSARKRIAKRR----------DCPHC 299
            ..|:.|.::|.|:..|..||.....|    :|.:.|  :...:.|.|:.:          .|..|
  Rat   462 WKCDICKKSFTRRPHLEEHMILHSQD----KPFKCTYCEEHFKSRFARLKHQEKFHLGPFPCDIC 522

  Fly   300 GLSF-PVSSLTIHIR-RHTGDNPYKCDQCEKAFPRSQDLSLHMRQHTGERPSECKICSKKFISQN 362
            |..| ...:|..||. .|.|...:.|..|.|:......|..|:|.|:||:|..|.||.:.|...:
  Rat   523 GRQFNDTGNLKRHIECTHGGKRKWTCFICGKSVRERTTLKEHLRIHSGEKPHLCSICGQSFRHGS 587

  Fly   363 KLARHMRLHTGQRPYSCKMCSKSFVQSNDLKIHMRRHTGERPYQCGVCGESFVCGSHLNIHRNRK 427
            ....|:|:|...:.|.|..|.|:|::.:.|..|.:.|:||:.:||..||:.|....||.:| .:.
  Rat   588 SYRLHLRVHHDDKRYECDECGKTFIRHDHLTKHKKIHSGEKAHQCEECGKCFGRRDHLTVH-YKS 651

  Fly   428 GHLIAVIPGNEVEANFAADPY---VNARVNQRRSEDIERMRLQRIPENQLQQRLENLPKPDVPAM 489
            .||     |.:|...:.|..:   |..::.:.:|            ..::..|..:..||
  Rat   652 VHL-----GEKVWQKYKATFHQCDVCKKIFKGKS------------SLEMHFRTHSGEKP----- 694

  Fly   490 CYKCGVCEQKFKSGALLTVH--------------------RNKMSHYEIERVY--ENP------- 525
             |||.:|.|.|:....||.|                    |.....|.|:.|:  ::|
  Rat   695 -YKCQICNQSFRIKKTLTKHLVIHSDARPFNCQHCNATFKRKDKLKYHIDHVHGIKSPDDSLSTS 758

  Fly   526 ----------FGKNQKIIKAE 536
                      :..:.||.:||
  Rat   759 EEKLMSLPIEYSSDDKIFQAE 779

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3281	NP_650132.1	zf-AD	14..92	CDD:285071	22/111 (20%)
		C2H2 Zn finger	205..226	CDD:275368	5/20 (25%)
		C2H2 Zn finger	249..266	CDD:275368	5/16 (31%)
		COG5048	<294..>391	CDD:227381	31/108 (29%)
		C2H2 Zn finger	296..315	CDD:275368	7/20 (35%)
		zf-H2C2_2	307..330	CDD:290200	8/23 (35%)
		C2H2 Zn finger	323..343	CDD:275368	6/19 (32%)
		zf-H2C2_2	335..358	CDD:290200	10/22 (45%)
		C2H2 Zn finger	351..371	CDD:275368	6/19 (32%)
		zf-H2C2_2	364..388	CDD:290200	8/23 (35%)
		C2H2 Zn finger	379..399	CDD:275368	6/19 (32%)
		zf-H2C2_2	391..416	CDD:290200	10/24 (42%)
		C2H2 Zn finger	407..424	CDD:275368	6/16 (38%)
Zbtb41	NP_001178599.1	BTB	78..174	CDD:279045	7/30 (23%)
		BTB	90..174	CDD:197585	7/30 (23%)
		C2H2 Zn finger	362..382	CDD:275368	3/19 (16%)
		C2H2 Zn finger	390..410	CDD:275368	5/19 (26%)
		C2H2 Zn finger	423..441	CDD:275368	5/17 (29%)
		C2H2 Zn finger	464..484	CDD:275368	7/19 (37%)
		C2H2 Zn finger	492..509	CDD:275368	3/16 (19%)
		C2H2 Zn finger	519..540	CDD:275368	7/20 (35%)
		C2H2 Zn finger	548..568	CDD:275368	6/19 (32%)
		zf-H2C2_2	561..585	CDD:290200	11/23 (48%)
		C2H2 Zn finger	576..596	CDD:275368	6/19 (32%)
		zf-C2H2	602..624	CDD:278523	7/21 (33%)
		C2H2 Zn finger	604..624	CDD:275368	6/19 (32%)
		zf-H2C2_2	616..641	CDD:290200	10/24 (42%)
		C2H2 Zn finger	632..650	CDD:275368	7/18 (39%)
		C2H2 Zn finger	669..686	CDD:275368	2/28 (7%)
		zf-H2C2_2	681..704	CDD:290200	8/28 (29%)
		C2H2 Zn finger	697..717	CDD:275368	7/19 (37%)
		C2H2 Zn finger	725..742	CDD:275368	2/16 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000