DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3281 and ZBTB11

DIOPT Version :9

Sequence 1:NP_650132.1 Gene:CG3281 / 41445 FlyBaseID:FBgn0260741 Length:538 Species:Drosophila melanogaster
Sequence 2:NP_055230.2 Gene:ZBTB11 / 27107 HGNCID:16740 Length:1053 Species:Homo sapiens


Alignment Length:507 Identity:118/507 - (23%)
Similarity:193/507 - (38%) Gaps:118/507 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    82 VENAHETLQ---------------NLFEQQEVAAKPDEVHVDVVE--LIDQDDVVSMAQYLSTSF 129
            |.|.|..|.               |....:::.|:....|...|:  |.||:::|  |....|.|
Human   434 VSNIHPKLSKENVISSSPEDSGMGNDISAEDICAEDIPKHRQKVDQPLKDQENLV--ASTAKTDF 496

  Fly   130 AEQ---------------------HVEMEEKYGDQDCSAFTSDVGEEPLYASEDRDDEPEDSFQL 173
            ...                     |..||:|.                    :.|...|:.:.|.
Human   497 GPDDDTYRSRLRQRSVNEGAYIRLHKGMEKKL--------------------QKRKAVPKSAVQQ 541

  Fly   174 KPRPDEIENRELSRPSQLGSRLNHSANFIYKCAVCPRVFAKSESLTRHFSQAHKLTADVAAMKLA 238
            ..:......:::.:|.:........|:  :||..|..||.:..:|..|              ||.
Human   542 VAQKLVQRGKKMKQPKRDAKENTEEAS--HKCGECGMVFQRRYALIMH--------------KLK 590

  Fly   239 NESCGTGLLTCEHCPRTFKRQDTLRRHM-QAFHPDAIALEPEETTDNSA------RKRIAKRRDC 296
            :|....  ..|..|.:.|:...:||.|: :....||.:.....:|.|.|      :.|..:...|
Human   591 HERARD--YKCPLCKKQFQYSASLRAHLIRHTRKDAPSSSSSNSTSNEASGTSSEKGRTKREFIC 653

  Fly   297 PHCGLSFP-VSSLTIHIRRHTGDNPYKCDQCEKAFPRSQDLSLHMRQHTGERPSECKICSKKFIS 360
            ..||.:.| :.||.||:.:|||..|:.|..|.|.|.....|.||...|..::..:|::|.|.|::
Human   654 SICGRTLPKLYSLRIHMLKHTGVKPHACQVCGKTFIYKHGLKLHQSLHQSQKQFQCELCVKSFVT 718

  Fly   361 QNKLARHMRLHTGQRPYSCKMCSKSFVQSNDLKIHMRRHTGE---RPYQCGVCGESFVCGSHLNI 422
            :..|..||.:|||:..|.|.:|.|||.:.:.|..|.::|..:   |.|.|..|.:||.....|..
Human   719 KRSLQEHMSIHTGESKYLCSVCGKSFHRGSGLSKHFKKHQPKPEVRGYHCTQCEKSFFEARDLRQ 783

  Fly   423 HRNRKGHLIAVIP----------------GNEVEANFAADPYVNARVNQRRSEDIERMRLQRIPE 471
            |.|:  || .|.|                .:.|:::...:||   |.|....|..|:...:|..:
Human   784 HMNK--HL-GVKPFQCQFCDKCYSWKKDWYSHVKSHSVTEPY---RCNICGKEFYEKALFRRHVK 842

  Fly   472 NQLQQRLENLPKPDVPAMCYKCGVCEQKFKSGALLTVHRNKMSHYEIERVYE 523
            .....: :...|.::..:|.|||   :||..   |..:|..|:::|..:.:|
Human   843 KATHGK-KGRAKQNLERVCEKCG---RKFTQ---LREYRRHMNNHEGVKPFE 887

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3281NP_650132.1 zf-AD 14..92 CDD:285071 4/24 (17%)
C2H2 Zn finger 205..226 CDD:275368 6/20 (30%)
C2H2 Zn finger 249..266 CDD:275368 5/16 (31%)
COG5048 <294..>391 CDD:227381 36/97 (37%)
C2H2 Zn finger 296..315 CDD:275368 8/19 (42%)
zf-H2C2_2 307..330 CDD:290200 11/22 (50%)
C2H2 Zn finger 323..343 CDD:275368 7/19 (37%)
zf-H2C2_2 335..358 CDD:290200 7/22 (32%)
C2H2 Zn finger 351..371 CDD:275368 7/19 (37%)
zf-H2C2_2 364..388 CDD:290200 12/23 (52%)
C2H2 Zn finger 379..399 CDD:275368 7/19 (37%)
zf-H2C2_2 391..416 CDD:290200 9/27 (33%)
C2H2 Zn finger 407..424 CDD:275368 5/16 (31%)
ZBTB11NP_055230.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 141..173
BTB 204..305 CDD:279045
BTB 215..306 CDD:197585
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 546..566 1/19 (5%)
C2H2 Zn finger 571..591 CDD:275368 8/33 (24%)
C2H2 Zn finger 599..619 CDD:275368 6/19 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 619..643 5/23 (22%)
C2H2 Zn finger 653..673 CDD:275368 8/19 (42%)
zf-H2C2_2 665..690 CDD:290200 12/24 (50%)
C2H2 Zn finger 681..701 CDD:275368 7/19 (37%)
C2H2 Zn finger 709..729 CDD:275368 7/19 (37%)
zf-H2C2_2 721..746 CDD:290200 12/24 (50%)
C2H2 Zn finger 737..757 CDD:275368 7/19 (37%)
C2H2 Zn finger 768..788 CDD:275368 7/21 (33%)
zf-H2C2_2 780..804 CDD:290200 7/26 (27%)
C2H2 Zn finger 796..816 CDD:275368 1/19 (5%)
C2H2 Zn finger 860..880 CDD:275368 9/25 (36%)
C2H2 Zn finger 888..908 CDD:275368 118/507 (23%)
zf-H2C2_2 900..923 CDD:290200
C2H2 Zn finger 916..937 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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