DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3281 and BCL6B

DIOPT Version :9

Sequence 1:NP_650132.1 Gene:CG3281 / 41445 FlyBaseID:FBgn0260741 Length:538 Species:Drosophila melanogaster
Sequence 2:NP_862827.2 Gene:BCL6B / 255877 HGNCID:1002 Length:479 Species:Homo sapiens


Alignment Length:295 Identity:82/295 - (27%)
Similarity:118/295 - (40%) Gaps:52/295 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   138 EKYGDQDCSAFTSDVGEEPLYASEDRDDEPEDSFQLKPRPDEIENRELSRPSQLGSRLNHSANFI 202
            |:...|.|.......|:|...:|.......|:.    |.|.         |.   |||:.:|..:
Human   215 ERSSGQPCPQARLPSGDEASSSSSSSSSSSEEG----PIPG---------PQ---SRLSPTAATV 263

  Fly   203 -YKC---AVCPRVFAKSESLTRHFSQAHKLTADVAAMKLANESCGTGLLTCEHCPRTFKRQDTLR 263
             :||   |..|.:..         |||...:.  :..:.|....|:...:|::|.........| 
Human   264 QFKCGAPASTPYLLT---------SQAQDTSG--SPSERARPLPGSEFFSCQNCEAVAGCSSGL- 316

  Fly   264 RHMQAFHPDAIALEPEETTDNSARKRIAKRRDCPHCGLSFPV-SSLTIHIRRHTGDNPYKCDQCE 327
                    |::....|:           |...|..|..||.. .:|..|...|||:.||.|..|.
Human   317 --------DSLVPGDED-----------KPYKCQLCRSSFRYKGNLASHRTVHTGEKPYHCSICG 362

  Fly   328 KAFPRSQDLSLHMRQHTGERPSECKICSKKFISQNKLARHMRLHTGQRPYSCKMCSKSFVQSNDL 392
            ..|.|..:|..|.|.|:||:|.:|:.|..:|:....|..|:.:|||::||.|..|...|.....|
Human   363 ARFNRPANLKTHSRIHSGEKPYKCETCGSRFVQVAHLRAHVLIHTGEKPYPCPTCGTRFRHLQTL 427

  Fly   393 KIHMRRHTGERPYQCGVCGESFVCGSHLNIHRNRK 427
            |.|:|.||||:||.|..||..|...|.|.:|..:|
Human   428 KSHVRIHTGEKPYHCDPCGLHFRHKSQLRLHLRQK 462

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3281NP_650132.1 zf-AD 14..92 CDD:285071
C2H2 Zn finger 205..226 CDD:275368 5/23 (22%)
C2H2 Zn finger 249..266 CDD:275368 3/16 (19%)
COG5048 <294..>391 CDD:227381 35/97 (36%)
C2H2 Zn finger 296..315 CDD:275368 6/19 (32%)
zf-H2C2_2 307..330 CDD:290200 9/22 (41%)
C2H2 Zn finger 323..343 CDD:275368 7/19 (37%)
zf-H2C2_2 335..358 CDD:290200 9/22 (41%)
C2H2 Zn finger 351..371 CDD:275368 5/19 (26%)
zf-H2C2_2 364..388 CDD:290200 10/23 (43%)
C2H2 Zn finger 379..399 CDD:275368 7/19 (37%)
zf-H2C2_2 391..416 CDD:290200 14/24 (58%)
C2H2 Zn finger 407..424 CDD:275368 6/16 (38%)
BCL6BNP_862827.2 BTB_POZ 19..132 CDD:365784
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 143..190
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 210..259 13/59 (22%)
C2H2 Zn finger 330..350 CDD:275368 6/19 (32%)
COG5048 354..>411 CDD:227381 21/56 (38%)
C2H2 Zn finger 358..378 CDD:275368 7/19 (37%)
zf-H2C2_2 370..395 CDD:372612 10/24 (42%)
C2H2 Zn finger 386..406 CDD:275368 5/19 (26%)
zf-C2H2 412..434 CDD:333835 8/21 (38%)
C2H2 Zn finger 414..434 CDD:275368 7/19 (37%)
zf-H2C2_2 427..451 CDD:372612 14/23 (61%)
C2H2 Zn finger 442..460 CDD:275368 7/17 (41%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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