back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3281 and Zfp60

DIOPT Version :9

Sequence 1:	NP_650132.1	Gene:	CG3281 / 41445	FlyBaseID:	FBgn0260741	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_033586.2	Gene:	Zfp60 / 22718	MGIID:	99207	Length:	704	Species:	Mus musculus

Alignment Length:	540	Identity:	134/540 - (24%)
Similarity:	195/540 - (36%)	Gaps:	174/540 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IHVNISSQTCRVCLE--THETNLYVHDEIKYNDLKLELWQLLEAVSKLKWTWTDPNLPMHLCQNC 68
            ||..:....|.||.:  ...:||..|.:|...|                       .|.| |:.|
Mouse   278 IHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSED-----------------------RPFH-CKVC 318

  Fly    69 ARRLIGAYEFIVEV---ENAHETLQNLFEQQEVAAKPDEVHVDVVELIDQDDVVSMAQYLSTSFA 130
            .:    |:..:.::   ||.| |....||.::..                 .:.|...||...:
Mouse   319 GK----AFTVLAQLTRHENIH-TEDKSFECKQCG-----------------KIFSNGSYLLRHY- 360

  Fly   131 EQHVEMEEKYGDQDC-SAFTSDVGEEPLYASEDR----DDEP------EDSFQLKPRPDEIENRE 184
            :.|.. |:.:....| .||...     ||.||.:    |::|      |.:|:.|        .:
Mouse   361 DTHTN-EKPFECNICGKAFRLH-----LYLSEHQKTHTDEKPFKCKLCESAFRRK--------YQ 411

  Fly   185 LSRPSQLGSRLNHSANFIYKCAVCPRVFAKSESLTRHFSQAHKLTADVAAMKLANESCGTGL--L 247
            ||...::     |:....|:|..|.:.|.:..:.|.|                  :|..||.  .
Mouse   412 LSEHQRI-----HTDVKPYQCKDCGKFFRRRSNFTEH------------------QSIHTGKKPF 453

  Fly   248 TCEHCPRTFKRQDTLRRHMQAFHPDAIALEPEE--------------TTDNSARKRIAKRRDCPH 298
            .|:.|.:.|:....|.|| |.||.|....|.:|              .|.::.:...    :|..
Mouse   454 ECKDCGKVFRLNIHLIRH-QRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPF----ECKE 513

  Fly   299 CGLSFP-VSSLTIHIRRHTGDNPYKCDQCEKAFPRSQDLSLHMRQHTGERPSECKICSKKFISQN 362
            ||.||. ||||..|...|:|..||||:.|.:||.|..:|..|.:.|:.|||.|||.|.|.|....
Mouse   514 CGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLA 578

  Fly   363 KLARHMRLHTGQ----------------------------RPYSCKMCSKSFVQSNDLKIHMRRH 399
            :|.||..:|.|:                            :|:.||.|.|.||:|..|:||.|.|
Mouse   579 QLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGKGFVRSTGLRIHERIH 643

  Fly   400 TGERPYQCGVCGESFVCGSHLNIHRNRKGHLIAVIPGNEVEANFAADPYVNARVNQRRSEDIERM 464
            |||:|:||..|||:|      ..|....||.......|..|.:.....:...|
Mouse   644 TGEKPFQCKECGEAF------QYHYQFLGHFRIHTGKNPYECSECGKYFTYGR------------ 690

  Fly   465 RLQRIPENQLQQRLENLPKP 484
                  :.::.|.:.||.||
Mouse   691 ------DLKVHQSIHNLEKP 704

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.