DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3281 and ZNF550

DIOPT Version :9

Sequence 1:NP_650132.1 Gene:CG3281 / 41445 FlyBaseID:FBgn0260741 Length:538 Species:Drosophila melanogaster
Sequence 2:NP_001264019.1 Gene:ZNF550 / 162972 HGNCID:28643 Length:422 Species:Homo sapiens


Alignment Length:229 Identity:79/229 - (34%)
Similarity:109/229 - (47%) Gaps:36/229 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   197 HSANFIYKCAVCPRVFAKSESLTRHFSQAHKLTADVAAMKLANESCGTGLLTCEHCPRTFKRQDT 261
            |:....|:|..|.:.|::|.:|.||: ..|               .|.....|..|.:.|||:..
Human   225 HTGMKPYECNACGKAFSQSSTLIRHY-LIH---------------TGEKPYKCLECGKAFKRRSY 273

  Fly   262 LRRHMQAFHPDAIALEPEETTDNSARKRIAKRRDCPHCGLSFPVSSLTI-HIRRHTGDNPYKCDQ 325
            |.:|    ||.....:|.|               |..|..:|...|..| |.|.|||:.|::|.:
Human   274 LMQH----HPIHTGEKPYE---------------CSQCRKAFTHRSTFIRHNRTHTGEKPFECKE 319

  Fly   326 CEKAFPRSQDLSLHMRQHTGERPSECKICSKKFISQNKLARHMRLHTGQRPYSCKMCSKSFVQSN 390
            |||||.....|..|...||||:|.:|..|.|.|...::|.:|.|:|||::||.|..|.|:|.:|.
Human   320 CEKAFSNRAHLIQHYIIHTGEKPYDCMACGKAFRCSSELIQHQRIHTGEKPYECTQCGKAFHRST 384

  Fly   391 DLKIHMRRHTGERPYQCGVCGESFVCGSHLNIHR 424
            .|..|...||||.||:|..||::|...|||..|:
Human   385 YLIQHSVIHTGEMPYKCIECGKAFKRRSHLLQHQ 418

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3281NP_650132.1 zf-AD 14..92 CDD:285071
C2H2 Zn finger 205..226 CDD:275368 7/20 (35%)
C2H2 Zn finger 249..266 CDD:275368 6/16 (38%)
COG5048 <294..>391 CDD:227381 41/97 (42%)
C2H2 Zn finger 296..315 CDD:275368 7/19 (37%)
zf-H2C2_2 307..330 CDD:290200 12/23 (52%)
C2H2 Zn finger 323..343 CDD:275368 8/19 (42%)
zf-H2C2_2 335..358 CDD:290200 10/22 (45%)
C2H2 Zn finger 351..371 CDD:275368 7/19 (37%)
zf-H2C2_2 364..388 CDD:290200 12/23 (52%)
C2H2 Zn finger 379..399 CDD:275368 7/19 (37%)
zf-H2C2_2 391..416 CDD:290200 12/24 (50%)
C2H2 Zn finger 407..424 CDD:275368 7/16 (44%)
ZNF550NP_001264019.1 KRAB 12..72 CDD:214630
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 113..158
COG5048 <200..357 CDD:227381 50/166 (30%)
C2H2 Zn finger 205..225 CDD:275368 79/229 (34%)
C2H2 Zn finger 233..253 CDD:275368 7/20 (35%)
C2H2 Zn finger 261..281 CDD:275368 9/23 (39%)
C2H2 Zn finger 289..309 CDD:275368 7/19 (37%)
C2H2 Zn finger 317..337 CDD:275368 8/19 (42%)
C2H2 Zn finger 345..365 CDD:275368 7/19 (37%)
zf-H2C2_2 357..382 CDD:404364 12/24 (50%)
C2H2 Zn finger 373..393 CDD:275368 7/19 (37%)
zf-H2C2_2 385..410 CDD:404364 12/24 (50%)
C2H2 Zn finger 401..421 CDD:275368 8/18 (44%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165146747
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.840

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