DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG3281 and Bcl6b

DIOPT Version :9

Sequence 1:NP_650132.1 Gene:CG3281 / 41445 FlyBaseID:FBgn0260741 Length:538 Species:Drosophila melanogaster
Sequence 2:NP_031554.1 Gene:Bcl6b / 12029 MGIID:1278332 Length:474 Species:Mus musculus


Alignment Length:294 Identity:82/294 - (27%)
Similarity:117/294 - (39%) Gaps:72/294 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   141 GDQDCSAFTSDVGEEPLYASEDRDDEPEDSFQLKPRPDEIENRELSRPSQLGSRLNHSANFI-YK 204
            ||:.||:.:|                               :.|.:.|. |.|||:.:.... :|
Mouse   229 GDEACSSSSS-------------------------------SEEGTTPG-LQSRLSLATTTARFK 261

  Fly   205 CAVCPRVFAKSESLTRHFSQAHKLTADVAAMKLANESCGTGLLTCEHCPRTFKRQDTLRRHMQAF 269
            |.    ..|.:..|....:|...|.|.    |.||...|:...:|::|                 
Mouse   262 CG----ALANNSYLFTPRAQETSLPAS----KQANPPPGSEFFSCQNC----------------- 301

  Fly   270 HPDAIA-----LEPEETTDNSARKRIAKRRDCPHCGLSFPV-SSLTIHIRRHTGDNPYKCDQCEK 328
              :|:|     ||.....|..      |...|..|..:|.. .:|..|...|||:.||:|..|..
Mouse   302 --EAVAGCSSGLELLAPGDED------KPYKCQLCRSAFRYKGNLASHRTVHTGEKPYRCSICGA 358

  Fly   329 AFPRSQDLSLHMRQHTGERPSECKICSKKFISQNKLARHMRLHTGQRPYSCKMCSKSFVQSNDLK 393
            .|.|..:|..|.|.|:||:|.:|:.|..:|:....|..|:.:|||::||.|..|...|.....||
Mouse   359 RFNRPANLKTHSRIHSGEKPYKCETCGSRFVQVAHLRAHVLIHTGEKPYPCPTCGTRFRHLQTLK 423

  Fly   394 IHMRRHTGERPYQCGVCGESFVCGSHLNIHRNRK 427
            .|:|.||||:||.|..||..|...|.|.:|..:|
Mouse   424 SHVRIHTGEKPYHCDPCGLHFRHKSQLRLHLRQK 457

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3281NP_650132.1 zf-AD 14..92 CDD:285071
C2H2 Zn finger 205..226 CDD:275368 4/20 (20%)
C2H2 Zn finger 249..266 CDD:275368 2/16 (13%)
COG5048 <294..>391 CDD:227381 34/97 (35%)
C2H2 Zn finger 296..315 CDD:275368 5/19 (26%)
zf-H2C2_2 307..330 CDD:290200 9/22 (41%)
C2H2 Zn finger 323..343 CDD:275368 7/19 (37%)
zf-H2C2_2 335..358 CDD:290200 9/22 (41%)
C2H2 Zn finger 351..371 CDD:275368 5/19 (26%)
zf-H2C2_2 364..388 CDD:290200 10/23 (43%)
C2H2 Zn finger 379..399 CDD:275368 7/19 (37%)
zf-H2C2_2 391..416 CDD:290200 14/24 (58%)
C2H2 Zn finger 407..424 CDD:275368 6/16 (38%)
Bcl6bNP_031554.1 BTB 28..132 CDD:279045
BTB 39..131 CDD:197585
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 144..190
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 210..249 8/51 (16%)
C2H2 Zn finger 325..345 CDD:275368 5/19 (26%)
zf-H2C2_2 337..362 CDD:290200 10/24 (42%)
C2H2 Zn finger 353..373 CDD:275368 7/19 (37%)
zf-H2C2_2 365..390 CDD:290200 10/24 (42%)
C2H2 Zn finger 381..401 CDD:275368 5/19 (26%)
zf-H2C2_2 393..418 CDD:290200 10/24 (42%)
C2H2 Zn finger 409..429 CDD:275368 7/19 (37%)
zf-H2C2_2 422..446 CDD:290200 14/23 (61%)
C2H2 Zn finger 437..455 CDD:275368 7/17 (41%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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