DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3281 and ZNF705E

DIOPT Version :9

Sequence 1:NP_650132.1 Gene:CG3281 / 41445 FlyBaseID:FBgn0260741 Length:538 Species:Drosophila melanogaster
Sequence 2:NP_001265642.1 Gene:ZNF705E / 100131539 HGNCID:33203 Length:300 Species:Homo sapiens


Alignment Length:219 Identity:71/219 - (32%)
Similarity:97/219 - (44%) Gaps:61/219 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   258 RQDTLRR-HMQAFHP----DA----------IALEPEETTDNSARKRIAKRRDCPH--------- 298
            |:..|:: ||.:.||    ||          |..:|.|..|:.        .||.|         
Human    80 RESALKKTHMISMHPIIRKDAPTSMTMENSLILEDPFECNDSG--------EDCTHSSTIIQCLL 136

  Fly   299 ------------CGLSFPVSSLTI---HIRRHTGDNPYKCDQCEKAFPRSQDLSLHMRQ----HT 344
                        ||.|  :|:|..   |.:.||....|:|:.||||:..    ..|:|:    ||
Human   137 THSGKKPYVSKQCGKS--LSNLLSPKPHKQIHTKGKSYQCNLCEKAYTN----CFHLRRPKMTHT 195

  Fly   345 GERPSECKICSKKFISQNKLARHMRLHTGQRPYSCKMCSKSFVQSNDLKIHMRRHTGERPYQCGV 409
            ||||..|.:|.|.|...:.|.||.:.|||:|||.|..|.|:|:||.:|:.|.|.|.||:.|:|..
Human   196 GERPYTCHLCRKAFTQCSHLRRHEKTHTGERPYKCHQCGKAFIQSFNLRRHERTHLGEKWYECDN 260

  Fly   410 CGESFVCGSHLN----IHRNRKGH 429
            .|::|...|...    ||...|.|
Human   261 SGKAFSQSSGFRGNKIIHTGEKPH 284

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3281NP_650132.1 zf-AD 14..92 CDD:285071
C2H2 Zn finger 205..226 CDD:275368
C2H2 Zn finger 249..266 CDD:275368 2/8 (25%)
COG5048 <294..>391 CDD:227381 44/124 (35%)
C2H2 Zn finger 296..315 CDD:275368 8/42 (19%)
zf-H2C2_2 307..330 CDD:290200 9/25 (36%)
C2H2 Zn finger 323..343 CDD:275368 7/23 (30%)
zf-H2C2_2 335..358 CDD:290200 11/26 (42%)
C2H2 Zn finger 351..371 CDD:275368 7/19 (37%)
zf-H2C2_2 364..388 CDD:290200 13/23 (57%)
C2H2 Zn finger 379..399 CDD:275368 9/19 (47%)
zf-H2C2_2 391..416 CDD:290200 10/24 (42%)
C2H2 Zn finger 407..424 CDD:275368 5/20 (25%)
ZNF705ENP_001265642.1 KRAB 7..66 CDD:214630
C2H2 Zn finger 118..138 CDD:275368 4/27 (15%)
C2H2 Zn finger 147..166 CDD:275368 6/20 (30%)
C2H2 Zn finger 174..194 CDD:275368 7/23 (30%)
C2H2 Zn finger 202..222 CDD:275368 7/19 (37%)
zf-H2C2_2 214..239 CDD:316026 13/24 (54%)
C2H2 Zn finger 230..250 CDD:275368 9/19 (47%)
C2H2 Zn finger 258..278 CDD:275368 4/19 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165146591
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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