Protein Alignment CG14731 and LOC1277659

DIOPT Version :10

• Sequence 1: NP_650130.1
• Gene: CG14731 / 41442
• FlyBaseID: FBgn0037964
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_061513672.1
• Gene: LOC1277659 / 1277659
• VectorBaseID: AGAMI1_014120
• Length: 691
• Species: Anopheles gambiae
• Alignment Length: 694
• Identity: 213/694 - (30%)
• Similarity: 339/694 - (48%)
• Gaps: 104/694 - (14%)

  Fly    11 KKNSFRLILM-----CIILYVLINFREQV---EHKMKEQP----PIEGKPD------NKMLFVNS 57
            ||..|:::||     ..:||.:    |:.   ::...|.|    .:|.:.|      |...|||:
Mosquito    36 KKTRFKVLLMMGTVFACLLYAI----ERPFWWDYDALEAPLWNEALETRDDEQHFNYNSSYFVNT 96

  Fly    58 SQCQINSMDPFSPTAMYHMTPMPSSACPMIKLMK----PQSIDGMNYLYLIASAKELWKKL---- 114
            ..|:                 |||......::.|    |:.|:.:..| |.|..:.:|.:|
Mosquito    97 VGCK-----------------MPSFPVTNAQIQKFVERPEPIECVPAL-LEADERWIWFQLSMED 143

  Fly   115 -----GVRRLSDIFCAYKRFVRFNDFVNIYF-ESTLFRF-----SKLRNFTKVDSGNITLRVWCW 168
                 .|...|.|.|..:.|.|..|...... ..:.|.:     ::...|..|:..::.|:...:
Mosquito   144 IERHYNVTNASMIQCCVRSFERLTDQEEHQVGNESCFDYPERYDAREEEFAMVNCHHVGLKDPFY 208

  Fly   169 MDYGRLVYHDVFIFLPFPNPQKVNNSAPV----------KRLSVLILGIDSISHMHYQRYFSRVR 223
            .||        |.|:| |..:.|......          :||:|:|||||::|.::..|..::..
Mosquito   209 WDY--------FAFVP-PGKRAVEERLKTARREGLAEGEQRLNVMILGIDAVSRLNLHRQMNQTT 264

  Fly   224 D-LIEGLPHTELWGYNRVGQNSYPNLIPLLSGQSVDEVEAKSGCYGASGGTNFDRCHLLWHDFQA 287
            | |:..|...|::|||:||.|::||::|.|:|..::|:.|  .|...:..| ||.|..:|:.|..
Mosquito   265 DYLLNTLNGIEMFGYNKVGDNTFPNMVPALTGLDIEELGA--ACLPNASST-FDLCQFVWNKFGE 326

  Fly   288 AGYATIFGEDSRVAGTFTYVRPGFKKRPTDFYLRSVINEIHMRSTYFARGPLEIK-CSGDRVYHH 351
            |||.|::.|||...|||.|.:.||:::|||:|||:...:  |.|:......|..| |.|.|....
Mosquito   327 AGYRTVYAEDSSAMGTFNYGKKGFRRQPTDYYLRNFFRQ--MESSVGYNKKLNAKLCLGGRNPTR 389

  Fly   352 VLYDFIYRLLPHMQARMYDRGFFAFFWQTMGVHDYFQYGERADWEYYRIMRAL--KRRKILERTL 414
            ||.|:..:::....|   ....|:..|.....||:|......|.:|.:::..:  :.|..|.||:
Mosquito   390 VLLDYARKIVKTFGA---SEPVFSLLWGVGMTHDFFNNPALIDDDYRQVLEFMQEEHRHYLNRTV 451

  Fly   415 VLIVSDHGLRYGPFVDTFQGMRETSLPIMVAIYPRSLRERFPLAFANLEANAHRLVTTYDLHETL 479
            ::::||||:|:|.|.:|:|||.|...|.::.:.|...|..:|.|:.||..|..||.|.:||:|||
Mosquito   452 LILMSDHGIRWGSFRNTYQGMMEERQPFLIFVLPAWFRREYPAAYHNLRRNRLRLTTHFDLYETL 516

  Fly   480 KDVVDLENLSDERILNRTLRLRN----NHNVSLFLPIPEERSCFSARIPLHYCQCDGYVKIPWNV 540
            |:.:|:..|....|..||..|..    ...:|||||:|..|:|..|.|..|:|.|..:..:|.|.
Mosquito   517 KEFLDMSGLRTGSIRERTEELLEAKPIPRGISLFLPVPTTRTCEDAGIAPHWCTCHDHKPLPKND 581

  Fly   541 RSIQRIAKLAVANINRLLAPYPQCEQLELLNVEDA-------YLRKQHKLNKTIIVRLVTQPGNG 598
            ..:.:.|:.||..:|.||..||||..|.|.:::||       .:..:||.: .|.||.||:||:|
Mosquito   582 HQVIQAARFAVERVNHLLLEYPQCSVLHLNSIDDASVGMSPENITAKHKFS-DISVRFVTKPGDG 645

  Fly   599 HFDATVL--SKNETSLQGPITRTDQYRHQSFCAREAPIEIYCYC 640
            .|:|||.  |.|::.|.|.::||:.|..||||..:..:::||:|
Mosquito   646 EFEATVRIDSNNDSFLTGTVSRTNLYGKQSFCVDDYRLKLYCFC 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14731	NP_650130.1	DUF229	77..573	CDD:397236	166/532 (31%)
LOC1277659	XP_061513672.1	None