DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cad87A and Cad99C

DIOPT Version :10

Sequence 1:NP_731649.2 Gene:Cad87A / 41441 FlyBaseID:FBgn0037963 Length:1975 Species:Drosophila melanogaster
Sequence 2:NP_733314.1 Gene:Cad99C / 43528 FlyBaseID:FBgn0039709 Length:1706 Species:Drosophila melanogaster


Alignment Length:1835 Identity:427/1835 - (23%)
Similarity:682/1835 - (37%) Gaps:527/1835 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 GLLMICLGLTLAK--------GETNL------------------P--PVFTQTLNNIILYENVTV 42
            |||::.....|.|        |:||:                  |  |:|......|.|      
  Fly    17 GLLILLCSAVLGKSQMCEVETGQTNIILDIEESRESFIGQPTTPPELPIFGDPDTEIAL------ 75

  Fly    43 GTVVFRLEAYDPEGSPVTYGAIGADHFSVDPVSGNITLIKPLDREEKDT--LKFLVSIRDRVDPE 105
             .:||      |:|.|:         |.::  ...:.|::||||:|::.  :.|.||...|...:
  Fly    76 -NLVF------PKGQPI---------FQLN--GKKLQLLQPLDRDEENLSHIVFQVSCTTRSTGK 122

  Fly   106 GESERDNVVEVPITFIILDLNDNPPEFQNTPYEADVNEDAAVGTTIFDKITVKDRD--------- 161
            ..:       :||...:.|:|||.|.|.|||||..|.|...||||||..|...|:|         
  Fly   123 KRT-------IPIIVRVSDINDNAPRFMNTPYEVTVPESTPVGTTIFRNIQALDKDAGVNGLVEY 180

  Fly   162 IVGESLDLKCLPQQQSPEACRKFRL---HIIKRDATILEAAVVLNDTLNYNQRMVYHFQIEATDG 223
            .:.|........::.|.:....|.:   |         :..|.:..||::.:...|:..|.|:|.
  Fly   181 FIAEGSPNSTNVEKYSADGYGTFAISFPH---------QGQVTVAKTLDFEKIQTYYLTIVASDR 236

  Fly   224 PHKT------QTTFEARVKDVQDKPP--VFQGSLS----TVIDEDS---PINTL--VLTV----- 266
            ...|      .||....:.|..|..|  ::.|.:|    .:..|.|   |..:|  ||||     
  Fly   237 ARNTADRLSSTTTLTVNIADSNDLDPSFIYSGCVSLDGACINPEYSASVPAGSLLGVLTVLPERI 301

  Fly   267 HARDGDT-GEPRKIVYDLRT----NPNDYFLLDAQTGELRTAKPLDREALEDSTGIISLVIRARE 326
            .|.|.|| ..|  |.|...:    |..|||.:|..||.|:..|.:|....:.    ..::::|.|
  Fly   302 QAVDLDTINSP--IRYSFASGMPGNYADYFQIDESTGVLKQTKAVDTSTAKK----YDIIVKAEE 360

  Fly   327 LVNGVPSDDPLTSATAKATVTIRDVNDSPPVFNHKEYSVSLLENTLPGTPL------ALDMSVSD 385
            :     |..|....|||..:.::.|:.:|||.:..:....:.||:..||.:      .:....:|
  Fly   361 V-----SPGPQRFTTAKLEIFVKPVDANPPVISSSQAEGYVDENSPIGTRVLDAHGNPISFMTTD 420

  Fly   386 ADVGINSKFALRLDDVSGVFDVEPK------------LVTGYSQVNIRVANGTLDYENPNQRKFI 438
            ||:.                |.:||            .|||...:.:...|  ||.:.|...:|.
  Fly   421 ADLS----------------DSDPKPDYIYELTTPSFNVTGDGILVVNEEN--LDRDPPAPGRFK 467

  Fly   439 VLVVAEETDTNPRLSSTATITVSVLDANDNKPVFEQESYSASVSEAALPGQYIATITARDVDSGS 503
            ..|||.|..|| ..|:..::||.:.|.|||.|.....:..:..:......:.:..:||.|.|.|.
  Fly   468 FQVVAREPRTN-AASAPLSLTVHLRDVNDNAPKLAMVAPISITAGDQSESRLVTQVTATDNDEGP 531

  Fly   504 YGDSGIRYSLSGTGAELFHVNEQTGVISLANCHDNGESNRRERRDLNEDEHVEEDDGEGHLEMLS 568
              ::.:.||       ::||:            :||                        ::..:
  Fly   532 --NAVVTYS-------IYHVS------------NNG------------------------IQKFT 551

  Fly   569 MEAATREIGTEPTVQYTLITQAPEEQASSVPLPAPVPHAAPSGVPAATANDDKAPQTCLDYESET 633
            :.|.|.||.|:..:      .|.|:                                        
  Fly   552 INATTGEIRTQGRL------LAGEQ---------------------------------------- 570

  Fly   634 TYFLSYKATDDNGRGSASVVSLRISVTDA-NDSPPVCESPLYRASVDEGAVVFDSPLIVKARDAD 697
             |.::.:|||..|..|.::|  .:|||.. |..||..:.|:|...|.|||.:..:..:|.|.|.:
  Fly   571 -YSITVQATDIGGLSSQAIV--EVSVTPGPNTKPPRFQKPIYEVQVSEGAEINSTVTVVHAEDPE 632

  Fly   698 TMSRISYRIRGSEQVESIFDIDRETGQIIIRPNATLDVTNLNSDQLIFAVEANDGLFTAHCGVNI 762
            ..:.:...|.|::..:  |.:.:|:|.||:  ...||..:|...|||...|...|| ::...|||
  Fly   633 NDAVVYSIISGNDLRQ--FAVGQESGVIIV--IRKLDRESLTRYQLILKAEDTGGL-SSSATVNI 692

  Fly   763 TVRDVNNHVPNFEQQSYSAVVE-ENSEIGTSVERVHATDLDTGKNAELRYRIQQGSFDDFGIVET 826
            .|.|:|:..|.||..:...|.: |..:...||..|||||.|.|.|||:.|.|....  .|.|..|
  Fly   693 KVTDINDKNPEFEASTLPYVFQVEEGKAQASVGVVHATDADEGINAEITYSIPTDI--PFTINAT 755

  Fly   827 TGEVFVSRKLDFDRRNTYQLQIQASDQGTPSLTGTATLTINVQNSNDKDPYFVPATQHAEVRADA 891
            :||:..:::||:::.|.|:..:.|.|....:..|||::|:.|.:..|:    ||....|.:....
  Fly   756 SGEILTAKELDYEQLNEYKFVVTAKDGAPDARLGTASVTVMVLDLPDE----VPKFSDARIDVHI 816

  Fly   892 PPGQ---LVYTLIALDPDVANHNALEFAGTDDITAIDKEGKELPHYDQFKEYFKIS-RNGKVSVN 952
            |..:   ||.|:.|.|||          ...:||.:.::|.        .|.||:| ::|:|...
  Fly   817 PENEENFLVATVQAFDPD----------SMPEITYVLRKGN--------AELFKVSEKSGEVRTI 863

  Fly   953 KQLDRNLFAVMRINVLVTDSTAPNVQQGRG---LLIIQIIDVNKNPPRFNAPWSVEQPQIKLQMV 1014
            |.||   :...:.:.| |..|..|...|.|   ||::.:.|.|..||||   .:|..|   :.:.
  Fly   864 KGLD---YESQKQHQL-TIGTIENDGNGPGDTILLVVDVEDRNDLPPRF---ITVPDP---VTVN 918

  Fly  1015 EEQPVGTVLTTLQANDED----SSIGEFNISDN----DYFAINQTSGMIYTIARLDYEVVKE--V 1069
            ::|.:||::.||.|.|.|    .::..:.|...    .||.::..:|.:    |:..|:.||  .
  Fly   919 DDQGIGTIIATLPAIDGDGTSPGNVVRYEIVGRGKAPKYFQVDPDTGAV----RIRDELRKEEDT 979

  Fly  1070 KFQVTVS--DTGVPALTATADVVVDIINL---NDNDPKFSQSDYYFNVTENSPRGTVAGKVEAHD 1129
            ::||.:.  |.|.|.|::.|.:.||:.:|   .:|:.|..                  .|:|:..
  Fly   980 EYQVDIRAYDLGEPQLSSVAPLRVDVHHLLSSGNNEIKLD------------------NKLESGT 1026

  Fly  1130 G----DVGVFGEITYTLIGENNKYFSIDAYTGNV---MVANSSILDREQIKELTLSVVAQDKAPA 1187
            |    .:|:              .||.|:||.:|   |.|||           ||.::       
  Fly  1027 GMSSESIGL--------------AFSDDSYTTSVPESMEANS-----------TLKLI------- 1059

  Fly  1188 AVQKSATATIHINILDVNDNAPVFTRDVYNSTVAENAAYQPPAALLQVQAIDQDEGLYGDVRYII 1252
                                      .:.||..:.:.   |||                 .|...
  Fly  1060 --------------------------QIVNSKTSGDG---PPA-----------------FRCEF 1078

  Fly  1253 TAGNEMGLFKLDAQSGIVYPAQSLSGKHGAYELTISARDTQGSGT----------------MEST 1301
            .:||..|:|.|.            |..||...|.|...|.:...:                ::.|
  Fly  1079 VSGNGGGIFNLS------------SADHGCNLLLIQPLDFENKSSYSLQLRLTSHRYFVNPLKDT 1131

  Fly  1302 TKAIITVLRVNRHKPEFVIPAL---SNATIEIPGDIVQPDYLLLTVRAMDNDTEENGKVSYHL-- 1361
            |...|.|...|.:.|||....|   .:....:..:.:..|..:|.|||.|.|:.:.|.|.|.|  
  Fly  1132 TSVEIIVQDENDNAPEFEFNRLRGQQDTFYTVVTEEMDVDTTILQVRATDRDSGKFGTVRYTLYD 1196

  Fly  1362 QVNNRNEQQTGEFKIDEVTGELRAKTQLNRKNRANYDIILVARDAGNPPFES----LRLLSVSIV 1422
            ...||....|..|.:.|.||.||.......:|......::.|||:......|    .|::...:.
  Fly  1197 DDENRVNMPTSFFMMSEDTGVLRTAKHFKNENDFPLTFLVEARDSDGQEQGSHRTRARIVVNKLA 1261

  Fly  1423 DANENRPEFPDAS----NPYKVSINENSGRDVKIGHIQAASRSKHNR---------------DIF 1468
            |.|.....||:|:    ..|...:.|.  .|.|.|.:....|....:               ||:
  Fly  1262 DINRMALSFPNAAPSDLRNYYTELEEL--LDKKTGLVSGIERMSSQKYLAKNGSVIENPAATDIW 1324

  Fly  1469 YYMLLGNEDGAFYVDKLTGDIYTNKSLDREETDVYTLYILASIKADLHI----SEEERASFSIKT 1529
            :|::               |..|.:.:.|:::.|.|..:..:.:::|:|    :..|..||   .
  Fly  1325 FYLI---------------DPKTEQLVSRKDSIVETTLLEPAARSELNIALPRATAENISF---P 1371

  Fly  1530 LNRDNTVAKVAITVLDVNDNPPVFEKPIYYAGVNANAKMGAAITLVNATDADQGKNAKIEFMIVA 1594
            |.|...|.||...|...|:   ||...:            .||:||.......|    |.::.::
  Fly  1372 LERKEHVHKVKAAVAIDNE---VFPFTL------------IAISLVILILGTIG----IIYICIS 1417

  Fly  1595 SNLYK-----FGATKSTGSIVPSPFAISQDGRISANTI--MAEYNQDRFELEIVARELEQPQSSA 1652
            .:.||     .....||......|..::|....::.||  |.||......:.:.....:..|...
  Fly  1418 WSKYKNFKQRMRQYSSTNPPRYDPVIVNQQASSASETIANMKEYETQMLAMAVPPDVDDDLQLDF 1482

  Fly  1653 STKVNIWVFDGTQLV 1667
            |.|.:.:..|....:
  Fly  1483 SAKNHAFSLDNVSYI 1497

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cad87ANP_731649.2 Cadherin_repeat 33..128 CDD:206637 22/96 (23%)
Cadherin_repeat 136..240 CDD:206637 29/121 (24%)
Cadherin_repeat 248..353 CDD:206637 34/123 (28%)
Cadherin_repeat 362..468 CDD:206637 29/123 (24%)
Cadherin_repeat 476..>533 CDD:206637 9/56 (16%)
CA_like <627..667 CDD:481204 11/40 (28%)
CA 692..772 CDD:214520 24/79 (30%)
Cadherin_repeat 778..873 CDD:206637 32/95 (34%)
Cadherin_repeat 882..994 CDD:206637 31/118 (26%)
Cadherin_repeat 1015..1099 CDD:206637 26/98 (27%)
Cadherin_repeat 1108..1207 CDD:206637 16/105 (15%)
Cadherin_repeat 1215..1314 CDD:206637 22/114 (19%)
Cadherin_repeat 1327..1427 CDD:206637 28/105 (27%)
Cadherin_repeat 1437..1549 CDD:206637 26/130 (20%)
Cadherin_repeat 1557..1662 CDD:206637 20/111 (18%)
Cad99CNP_733314.1 CA_like 68..140 CDD:481204 24/102 (24%)
Cadherin_repeat 146..259 CDD:206637 29/121 (24%)
Cadherin_repeat 280..383 CDD:206637 33/113 (29%)
Cadherin_repeat 393..496 CDD:206637 29/121 (24%)
Cadherin_repeat 518..594 CDD:206637 26/169 (15%)
Cadherin_repeat 608..699 CDD:206637 29/95 (31%)
Cadherin_repeat 710..802 CDD:206637 32/93 (34%)
Cadherin_repeat 814..903 CDD:206637 29/110 (26%)
Cadherin_repeat 915..1005 CDD:206637 24/93 (26%)
Cadherin_repeat 1041..1144 CDD:206637 31/178 (17%)
Cadherin_repeat 1159..1264 CDD:206637 27/104 (26%)

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