Protein Alignment Cad87A and Pcdhb1

DIOPT Version :9

• Sequence 1: NP_731649.2
• Gene: Cad87A / 41441
• FlyBaseID: FBgn0037963
• Length: 1975
• Species: Drosophila melanogaster
• Sequence 2: XP_001054930.1
• Gene: Pcdhb1 / 364841
• RGDID: 1308760
• Length: 818
• Species: Rattus norvegicus
• Alignment Length: 964
• Identity: 216/964 - (22%)
• Similarity: 376/964 - (39%)
• Gaps: 233/964 - (24%)

  Fly  1009 IKLQMVEEQPVGTVLTTLQANDEDSSIGEFN------ISDND--YFAINQTSGMIYTIARLDYEV 1065
            |:..:.||...|:.:..: |.|....:|:..      :::.:  :|.:::.:|.::...:||.|.
  Rat    31 IRYSVAEEMESGSFVANV-AKDLGLEVGKLAERGARLVAEGNRLHFRLHRKTGDLFVKEKLDREA 94

  Fly  1066 V------KEVKFQVTVSDTGVPALTATADVVVDIINLNDNDPKFSQSDYYFNVTENSPRGTVAGK 1124
            :      ..:.|::.:::.     ..:..|.|.:.::|||.|.|...:....:.|::|.|:....
  Rat    95 LCGKADPCVLHFEIILAEP-----LQSFRVEVRVFDINDNAPVFLNKEPLLKIPESTPLGSRFPL 154

  Fly  1125 VEAHDGDVGVFGEITYTLIGENNKYFSIDA--------YTGNVMVANSSILDREQIKELTLSVVA 1181
            ..|.|.|||:.|...|||  ..|.||.:..        |...|:   .:.||||...|:.|::.|
  Rat   155 QSAQDLDVGLNGLQNYTL--SANTYFHLHTRFRSHGPKYAELVL---DNPLDREAQPEVNLTITA 214

  Fly  1182 QDKAPAAVQKSATATIHINILDVNDNAPVFTRDVYNSTVAENAAYQPPAALLQVQAIDQDEGLYG 1246
            .|  ..:..||.||.|.:.:|||||:.|.|:|.||.:.|.||:  ...:.::.|.|.|.|||...
  Rat   215 VD--GGSPPKSGTANIRVVVLDVNDHVPQFSRLVYRAQVPENS--DNGSLVVVVTATDLDEGTNK 275

  Fly  1247 DVRYIITAGNEMGL--FKLDAQSGIVYPAQSLSGKHG-----AYELTISARDTQGSGTMESTTKA 1304
            .:.|.:....|..|  |.:|.|:|.|    .|.|...     .|::.|.|.|   .|.:.:.:|.
  Rat   276 QITYSLAENPEAVLRTFLVDPQTGEV----RLRGPLDFETIETYDIDIQATD---GGGLSAHSKV 333

  Fly  1305 IITVLRVNRHKPEFVIPALSNATIEIPGDIVQPDYLLLTVRAMDNDTEENGKVSYHLQ-----VN 1364
            ::.|:.||.:.||..|.::|:...|  ...:|....|.|:|  |.|....||::..|:     |.
  Rat   334 LVEVVDVNDNPPEVTISSVSSPLAE--DSPLQTVVALFTIR--DRDVRVGGKITCFLKEDLPFVV 394

  Fly  1365 NRNEQQTGEFKIDEVTGELRAKTQLNRKNRANYDIILVARDAGNPPFESLRLLSVSIVDANENRP 1429
            ....:.:.....|.:         |:|::.:||:|.|||.|.|.|...:..::.|.|.|.|:|.|
  Rat   395 KHTFRNSYSLVTDRI---------LDREDVSNYNITLVAMDTGPPSLSTETVIEVVISDINDNSP 450

  Fly  1430 EFPDASNPYKVSINENSGRDVKIGHIQAASRSKHNRDIFYYMLLGNEDGAFYV------DKLTGD 1488
            .|.:.|  |.:::.||:...|.||.:.|............|.||..:.|...|      :...|.
  Rat   451 VFQEDS--YVLTVRENNSPAVFIGKVHAEDLDLGENAQVTYSLLPPKSGDLSVFAYISINSDNGK 513

  Fly  1489 IYTNKSLDREETDVYTLYILASIKADLHISEEERASFSIKTLNRDNTVAKVAITVLDVNDNPPVF 1553
            :|..:::|.|....:...:.|:....|.:|.:                ..|.:.|||.|||.|:.
  Rat   514 LYALRTMDYEAIQDFQFVVKATDGGFLSLSSQ----------------VTVRVVVLDDNDNRPMI 562

  Fly  1554 EKPIYYAGVNAN------AKMGAAITLVNATDADQGKNAKIEF-MIVASNLYKFGATKSTGSIVP 1611
            ..|:....:..|      |:.|..:|.|.|.|.|.|:|:.:.: ::.|::|..|...:
  Rat   563 LYPLQNGTLPCNDLVPRSAEAGYLVTKVVAVDGDSGQNSWLSYHLLKATDLGLFSVQR------- 620

  Fly  1612 SPFAISQDGRISANTIMAEYNQDRFELEIVARELEQPQSSASTKVNIWVFDGTQLVRVILSRPPE 1676
                  |:|.|.....::|.:....:|.|:.::..||..|.:..:||.:.||       .|.|
  Rat   621 ------QNGEIRTLRQISERDPMMQKLVILVQDHGQPALSTTASLNILLVDG-------FSEP-- 670

  Fly  1677 EVYQEQEEIIAELRNATQHRIIVDEIRFHLDSIGRIRMDWCDLYFHAVDPQTQQIAPVDEILKDI 1741
                     ..:.::.::|.                         ..|:|.|:
  Rat   671 ---------YLQFQDPSKHS-------------------------RKVNPTTK------------ 689

  Fly  1742 DRNYDYLKDYYAGFAIENVVPAYIAIVQDEFDLAVAGLVALVIVLFVGVISFIVLCCCLKHWNLS 1806
                                  |:.|     .|||   ::.:.:..|.||..|.|...:||
  Rat   690 ----------------------YLVI-----SLAV---LSFLFLFSVTVIIIIHLYQKIKH---- 720

  Fly  1807 VPVETRRKEALIKKQIIEDLNTTENPLWIEQKLKLYEEQELTMQVFSEPDHISNSEAPGHLDHR- 1870
                  |::..:::...:|.|...|.:.......|.:..         |..:.::...|:.:.|
  Rat   721 ------REKFTVQEHFYDDCNFPNNLVQGRGNGSLSQPC---------PYDMCSATGTGNSEFRF 770

  Fly  1871 -----SSLEQVHHVGQTVDNTYATIQPRNNQNRLTGGGGAGGGSMRSGGGASAG 1919
                 .:....|..|:......|::.|.:|:||..|          |.|.|.||
  Rat   771 LKRFMPNFPFPHATGEVKTENDASLPPDSNRNRSRG----------SEGHARAG 814

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad87A	NP_731649.2	Cadherin_repeat	33..128	CDD:206637
		Cadherin_repeat	136..240	CDD:206637
		Cadherin_repeat	248..353	CDD:206637
		Cadherin_repeat	362..468	CDD:206637
		Cadherin_repeat	476..>533	CDD:206637
		E_set	<627..667	CDD:298831
		CA	692..772	CDD:214520
		Cadherin_repeat	778..873	CDD:206637
		Cadherin_repeat	882..994	CDD:206637
		Cadherin_repeat	1015..1099	CDD:206637	15/97 (15%)
		Cadherin_repeat	1108..1207	CDD:206637	34/106 (32%)
		Cadherin_repeat	1215..1314	CDD:206637	30/105 (29%)
		Cadherin_repeat	1327..1427	CDD:206637	27/104 (26%)
		Cadherin_repeat	1437..1549	CDD:206637	24/117 (21%)
		Cadherin_repeat	1557..1662	CDD:206637	24/111 (22%)
Pcdhb1	XP_001054930.1	Cadherin_2	30..110	CDD:285466	13/79 (16%)
		Cadherin_repeat	140..238	CDD:206637	34/104 (33%)
		Cadherin_repeat	246..343	CDD:206637	30/105 (29%)
		CA	372..450	CDD:214520	24/88 (27%)
		Cadherin_repeat	456..558	CDD:206637	25/119 (21%)
		Cadherin_repeat	577..665	CDD:206637	23/100 (23%)
		Cadherin_C_2	688..772	CDD:293101	21/144 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000