Protein Alignment Cad87A and Cdh10

DIOPT Version :10

• Sequence 1: NP_731649.2
• Gene: Cad87A / 41441
• FlyBaseID: FBgn0037963
• Length: 1975
• Species: Drosophila melanogaster
• Sequence 2: NP_033995.1
• Gene: Cdh10 / 320873
• MGIID: 107436
• Length: 788
• Species: Mus musculus
• Alignment Length: 702
• Identity: 174/702 - (24%)
• Similarity: 269/702 - (38%)
• Gaps: 195/702 - (27%)

  Fly   450 PRLSSTATITVSVLDANDNKP------------------VFEQESYSASVSEAALPGQYIATITA 496
            |.|:...|..:..:.|....|                  .|..|.|:.|      ..||:..:.:
Mouse    22 PELTFRRTPGIQQMTAESRAPRSDGKILHRQKRGWMWNQFFLLEEYTGS------DYQYVGKLHS 80

  Fly   497 RDVDSGSYGDSGIRYSLSGTGA-ELFHVNEQTGVISLANCHDNGESNRRERRDLNEDEHVEEDDG 560
             |.|.   ||..::|.|||.|| .||.::|:||                       |.|
Mouse    81 -DQDK---GDGSLKYILSGDGAGTLFIIDEKTG-----------------------DIH------ 112

  Fly   561 EGHLEMLSMEAATREIGTEPTVQYTLITQAPEEQASSVPLPAPVPHAAPSGVPAATANDDKAPQT 625
                       |||.|..|....|||..||...                              :|
Mouse   113 -----------ATRRIDREEKAFYTLRAQAINR------------------------------RT 136

  Fly   626 CLDYESETTYFLSYKATDDNGRGSASVVSLRISVTDANDSPPVCESPLYRASVDEGAVVFDSPLI 690
            ....|.|:.:.                    |.:.|.||:.|.....:|.|||.|.:||..|.:.
Mouse   137 LRPVEPESEFV--------------------IKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQ 181

  Fly   691 VKARDADTMS-----RISYRIRGSEQVESIFDIDRETGQIIIR---PNATLDVTNLNSDQLIFAV 747
            |.|.|||..|     |:.|.|.   |.:..|.::.|||  |||   ||...:    |.:|....:
Mouse   182 VTATDADDPSYGNSARVIYSIL---QGQPYFSVEPETG--IIRTALPNMNRE----NKEQYQVVI 237

  Fly   748 EAND-----GLFTAHCGVNITVRDVNNHVPNFEQQSYSAVVEENSEIGTSVERVHATDLDTGKNA 807
            :|.|     |..:....||||:.|||::.|.|.|.:....|.|:|.:||:|..|.|||.||||||
Mouse   238 QAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAVGSVKATDADTGKNA 302

  Fly   808 ELRYRIQQGSFDD-FGIV----ETTGEVFVSRKLDFDRRNTYQLQIQASDQGTP-------SLTG 860
            |:.|||..|...| |.|:    ...|.:.|.:.||::.|..|.|:::|.:....       ....
Mouse   303 EVDYRIIDGDGTDMFDIITEKDTQEGIITVKKPLDYENRRLYTLKVEAENTHVDPRFYYLGPFKD 367

  Fly   861 TATLTINVQNSNDKDPYFVPATQHAEVRADAPPGQLVYTLIALDPDVANHNALEFAGTDDITAID 925
            |..:.|::::. |:.|.|..::...||..|...|.::.|::|.||| :..:.:.|. .|..|.:|
Mouse   368 TTIVKISIEDV-DEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPD-STSSPIRFT-LDRHTDLD 429

  Fly   926 KEGKELPHYDQFKEYFKI-SRNGKVSVNKQLDRNLFAVMRINVLVTDSTAPNVQQGRGLLIIQII 989
            :             .|.| |.||.:..:|.|||.|.....:.|:..:...|. :..|..:.::|:
Mouse   430 R-------------IFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPK-ETTRVSVFVRIL 480

  Fly   990 DVNKNPPRFNAPWSVEQPQIKLQMVEEQPVGTVLTTLQANDEDSSIG-------------EFNIS 1041
            |||.|.|:|...:..       .:.|....|.::.|:.|.|:|..:|             .|.:.
Mouse   481 DVNDNAPQFAVFYDT-------FVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPNFTVQ 538

  Fly  1042 DNDYFAINQTSGMIYTIARLDYEVVKEVKFQVTVSDTGVPALTATADVVVDI 1093
            ||:    :.|:.::......:...:......|.:||...|..::|..:.:.:
Mouse   539 DNE----DNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRV 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad87A	NP_731649.2	Cadherin_repeat	33..128	CDD:206637
		Cadherin_repeat	136..240	CDD:206637
		Cadherin_repeat	248..353	CDD:206637
		Cadherin_repeat	362..468	CDD:206637	4/17 (24%)
		Cadherin_repeat	476..>533	CDD:206637	19/57 (33%)
		CA_like	<627..667	CDD:481204	6/39 (15%)
		CA	692..772	CDD:214520	30/92 (33%)
		Cadherin_repeat	778..873	CDD:206637	34/106 (32%)
		Cadherin_repeat	882..994	CDD:206637	30/112 (27%)
		Cadherin_repeat	1015..1099	CDD:206637	16/92 (17%)
		Cadherin_repeat	1108..1207	CDD:206637
		Cadherin_repeat	1215..1314	CDD:206637
		Cadherin_repeat	1327..1427	CDD:206637
		Cadherin_repeat	1437..1549	CDD:206637
		Cadherin_repeat	1557..1662	CDD:206637
Cdh10	NP_033995.1	CA	80..158	CDD:214520	34/171 (20%)
		Cadherin_repeat	164..265	CDD:206637	39/109 (36%)
		Cadherin_repeat	273..380	CDD:206637	34/107 (32%)
		Cadherin_repeat	388..485	CDD:206637	30/112 (27%)
		Cadherin_repeat	493..587	CDD:206637	16/105 (15%)
		CADH_Y-type_LIR	721..780	CDD:460041