Protein Alignment Cad87A and Pcdha11

DIOPT Version :9

• Sequence 1: NP_731649.2
• Gene: Cad87A / 41441
• FlyBaseID: FBgn0037963
• Length: 1975
• Species: Drosophila melanogaster
• Sequence 2: NP_034090.1
• Gene: Pcdha11 / 12942
• MGIID: 1298372
• Length: 950
• Species: Mus musculus
• Alignment Length: 781
• Identity: 191/781 - (24%)
• Similarity: 315/781 - (40%)
• Gaps: 177/781 - (22%)

  Fly   701 RISYRIRGSEQVESIFDIDRETGQIIIRPNATLDVTNL--NSDQLIFAVE--ANDGLFTAHCGVN 761
            |::.:.||     .:.:::.:.|.:.:  |:.:|...|  .|.:....:|  .:..|...|  |.
Mouse    65 RVASKDRG-----DLLEVNLQNGILFV--NSRIDREELCGRSAECSIHLEVIVDRPLQVFH--VE 120

  Fly   762 ITVRDVNNHVPNFEQQSYSAVVEENSEIGTSVERVHATDLDTGKNAELRYRIQQGSFDDFGI--- 823
            :.|||:|::.|.|..:....::.|:.:..:......|:|.|.|:||.|.||:.|..:  |.:
Mouse   121 VEVRDINDNPPVFPLREQRLLISESKQPDSRFPLEGASDADIGENAVLVYRLSQNEY--FSLEPP 183

  Fly   824 ---VETTGEVFVSRKLDFDRRNTYQLQ--IQASDQGTPSLTGTATLTINVQNSNDKDPYFVPATQ 883
               .:|.....:.:|: .||..|.:|.  :.|:|.|.|.||||..|.:.|.:.||.||.|.....
Mouse   184 INSKQTKRPSLILKKV-LDREKTPELNLLLTATDGGKPELTGTVQLWVRVLDVNDNDPVFDHLEY 247

  Fly   884 HAEVRADAPPGQLVYTLIALDPDVANHNALEFAGTDDITAIDKEGKELPHYDQFKEYFKISRNGK 948
            ...:..:|....||.||.|.|.|...:..|.::    :.:|...|:.|...|:        :||:
Mouse   248 KVRIMENAAKETLVITLNATDLDEGANGQLVYS----LMSIKPTGRHLFTLDE--------KNGE 300

  Fly   949 VSVNKQLDRNLFAVMRINVLVTD-STAPNVQQGRGLLIIQIIDVNKNPPRFNAPWSVEQPQIKLQ 1012
            :.||..||.....:..|.||.|| .|.|.|  |..:::::|:|.|.|.|      .|....:.|.
Mouse   301 LRVNGTLDYEENKLYEIEVLATDKGTPPMV--GHCVVLVEILDTNDNSP------EVTLTSLSLP 357

  Fly  1013 MVEEQPVGTVLTTLQANDEDSSI-GEF--NISDNDYFAINQTSGMIYTI---ARLDYEVVKEVKF 1071
            :.|:....||:..:..:|.||.| |:.  :::.|..|.|..|....|::   :.||.|.|.....
Mouse   358 VREDAQPNTVIALISVSDLDSGINGQVTCSLTPNVPFKIVSTFKNYYSLVLDSSLDRERVSTYDL 422

  Fly  1072 QVTVSDTGVPALTATADVVVDIINLNDNDPKFSQSDYYFNVTENSPRGTVAGKVEAHDGDVGVFG 1136
            .|...|.|.|:|:||..|.|::.::|||.|.|:|.:|...|.||:|.|.....|.|.|.|.....
Mouse   423 VVIARDGGSPSLSATVSVSVEVADVNDNAPVFAQPEYTVFVKENNPPGAHIFTVSAMDADAQENA 487

  Fly  1137 EITYTL----IGEN--NKYFSIDAYTGNVMVANSSILDREQIKELTLSVVAQDKAPAAVQKSATA 1195
            .::|:|    :||.  :.|.|:.|.:|.|.....  ||.|:::.|...|.|:|....|:  .:..
Mouse   488 LVSYSLVERRVGERLLSSYVSVHAESGKVFALQP--LDHEELELLQFQVSARDAGVPAL--GSNV 548

  Fly  1196 TIHINILDVNDNAPVFTRDVYNSTVAENAAYQPPAALLQVQAIDQDEGLYGDVRYIITAGNEMGL 1260
            |:.:.:||.|||||...
Mouse   549 TLQVFVLDENDNAPTLL------------------------------------------------ 565

  Fly  1261 FKLDAQSGIVYPAQSLSGKHGAYELTISARDTQGSGTMESTTKAIITVLRVNRHKPEFVIPALSN 1325
                              .|||.          |:|                            .
Mouse   566 ------------------PHGAV----------GAG----------------------------G 574

  Fly  1326 ATIEIPGDIVQPDYLLLTVRAMDNDTEENGKVSYHLQVNNRNEQQTG----EFKIDEVTGELRAK 1386
            |..|:....|...:::..|||:|.|:..|..:||.:|:.      ||    .|::...|||:...
Mouse   575 AVSELVSRSVGSGHVVTKVRAVDADSGYNAWLSYEVQLG------TGGVRSPFRVGLYTGEISTT 633

  Fly  1387 TQLNRKNRANYDIILVARDAGNPPFESLRLLSVSIVDANENRPEFPDASNPYKVSINENSGRDVK 1451
            ..|:..:.....::::.:|.|.|...:...:.||:|::.:....|..||.  :.|..|.|..||.
Mouse   634 RALDEVDSPRQTLLVLVKDHGEPALTATATVLVSLVESGQAPKSFSQASG--RASAPEASLVDVN 696

  Fly  1452 I 1452
            :
Mouse   697 V 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad87A	NP_731649.2	Cadherin_repeat	33..128	CDD:206637
		Cadherin_repeat	136..240	CDD:206637
		Cadherin_repeat	248..353	CDD:206637
		Cadherin_repeat	362..468	CDD:206637
		Cadherin_repeat	476..>533	CDD:206637
		E_set	<627..667	CDD:298831
		CA	692..772	CDD:214520	16/74 (22%)
		Cadherin_repeat	778..873	CDD:206637	28/102 (27%)
		Cadherin_repeat	882..994	CDD:206637	31/112 (28%)
		Cadherin_repeat	1015..1099	CDD:206637	27/89 (30%)
		Cadherin_repeat	1108..1207	CDD:206637	31/104 (30%)
		Cadherin_repeat	1215..1314	CDD:206637	5/98 (5%)
		Cadherin_repeat	1327..1427	CDD:206637	24/103 (23%)
		Cadherin_repeat	1437..1549	CDD:206637	5/16 (31%)
		Cadherin_repeat	1557..1662	CDD:206637
Pcdha11	NP_034090.1	Cadherin_2	30..111	CDD:285466	9/52 (17%)
		Cadherin_repeat	137..238	CDD:206637	29/103 (28%)
		Cadherin_repeat	246..345	CDD:206637	31/112 (28%)
		Cadherin_repeat	353..450	CDD:206637	28/96 (29%)
		Cadherin_repeat	458..560	CDD:206637	31/105 (30%)
		Cadherin_repeat	580..669	CDD:206637	22/94 (23%)
		Cadherin_tail	799..942	CDD:292596

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7553
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.950