Protein Alignment Cad87A and LOC1279112

DIOPT Version :10

• Sequence 1: NP_731649.2
• Gene: Cad87A / 41441
• FlyBaseID: FBgn0037963
• Length: 1975
• Species: Drosophila melanogaster
• Sequence 2: XP_061509480.1
• Gene: LOC1279112 / 1279112
• VectorBaseID: AGAMI1_008768
• Length: 1570
• Species: Anopheles gambiae
• Alignment Length: 1112
• Identity: 247/1112 - (22%)
• Similarity: 425/1112 - (38%)
• Gaps: 341/1112 - (30%)

  Fly   655 LRISVTDANDSPPVCESPLYRASVDEGAVVFDSPLIVKARDADTMSRISYRIRGSEQVESIFDID 719
            ::....|.||.|...:...|...:||...:..:.|.|.|:.....:.:.|:| .|..::::|.|.
Mosquito   123 IKTGTADKNDYPLYFDKVFYEVDIDENVEINHNFLNVTAKTHAEAAGVRYKI-SSGNIDNVFAIR 186

  Fly   720 RETGQIIIRPNATLDVTNLNSDQLIFAVEANDGLFTAHCGVNITVRDVNNHVPNFEQQSYSAVV- 783
            ..||.:.:.  ..||...:...:|  .:.|:|.....:..|.|.|||||::.|.||:.|||..:
Mosquito   187 NATGALYVA--KALDYEKIKKYEL--RLMASDNFKENYTTVLINVRDVNDNPPVFEKSSYSTQIT 247

  Fly   784 -EENSEIGTSVERVHATDLDTGKNAELRY-------RIQQGSFDDFGIVETTGEVFVSRKLDFD- 839
             |:|..:...|.||.|:|.|..:...:.|       .|:..|..:|.|.:.|||:||.:.|:.|
Mosquito   248 EEDNRALPKRVLRVTASDADVDRLNNIIYFLTGPGIDIENPSDSNFDINKATGEIFVLKPLNRDP 312

  Fly   840 --RRNTYQLQIQASDQGTPSLTGTATLTINVQNSNDKDPYFVPATQHAEVRADAPPGQLVYTLIA 902
              .|.:::..:.|.|:|...|.|...:.||:::.||..|.|.....:..|..:...|..|.|:.|
Mosquito   313 PHGRASWKFTVFAQDEGGEGLVGFTEVQINLKDVNDNAPQFQNGIAYGNVTENGTIGMHVMTIKA 377

  Fly   903 LDPDVANHNALEFAGTDD--ITAIDK----EGKELPHYDQFKEYFKISRNGKVSVNKQ------- 954
            .|.|..|.      ||:.  |.:|:|    |...||.:|               :|..
Mosquito   378 EDYDDINE------GTNAKIIYSIEKNVIQEDTGLPIFD---------------INPATGLITTA 421

  Fly   955 ---LDRNLFAVMRINVLVTDSTAPNVQQGRGLLIIQIIDVNKNPPRFNA-PWSVEQPQIKLQMVE 1015
               |||.......:.::.||...   .:|.|...|::.|:|..||||.. .|.||..:....::.
Mosquito   422 VCCLDREKTPDYSLQIVATDGGG---LKGTGTASIKVKDLNDMPPRFTKDEWFVEVEETDGSVLP 483

  Fly  1016 EQPVGTVLTTLQANDEDSSIGEFNISDN-----DYFAINQT---SGMIYTIARLDYEVVKEV--- 1069
            |:|:.||  |:..:||.::. ::.|.::     |.||:.:.   :|.:..:..||||...::
Mosquito   484 EEPILTV--TVNDDDEINNF-QYKIIESIGYGVDKFAMVKNADGTGSLKVVQPLDYEDPMQINGF 545

  Fly  1070 KFQVTVSDTGVPALTATAD--------VVVDIINLNDNDPKFSQSDYYFNVTENSPRGTVAGKVE 1126
            :|::.|.|...   ...:|        |:|.:.::|||.|:|.:......|.||:..|...|..:
Mosquito   546 RFRIQVIDNDE---IDESDKYHVDHSWVIVKLKDINDNTPRFKKPHIEAAVYENADVGKNLGTFK 607

  Fly  1127 AHDGDVGVFGEITYTL--IGENNKYFSIDAYTGNVMVANSSILDREQIKELTLSVVAQDKAPAAV 1189
            |.|.|.|...:|||::  ..:..:.|:||.   ..||.....||||.:.:.:|.::|.|  ....
Mosquito   608 AVDIDKGGKSKITYSINRATDRKRQFAIDQ---EGMVTIQRELDREAMAKHSLEILATD--DGVP 667

  Fly  1190 QKSATATIHINILDVNDNAPVFTRDVYNSTVAENAAYQPPAALLQVQAIDQDEGLYGDVRYIITA 1254
            .::|:|.:.:.:.|:|||.|||..| |...:.||:   ||:.::::.|:|:|:.|
Mosquito   668 PRTASAILTVLVKDINDNTPVFAED-YRPILLENS---PPSKIIEISAVDKDDRL---------- 718

  Fly  1255 GNEMGLFKLDAQSGIVYPAQSLSGKHGAYELTISARDTQGSGTMESTTKAIITVLRVNRHKPEFV 1319
                                                  :|:|
Mosquito   719 --------------------------------------EGNG----------------------- 722

  Fly  1320 IPALSNATIEIPGDIVQPDYLLLTVRAMDNDTEENGKVSYHLQVNNRNE-----QQTGEFKIDEV 1379
                  |..:.               :||.:.::..:.|:.::.:|:.:     ...|.|
Mosquito   723 ------APFQF---------------SMDPNADDVIRTSFKVEQSNKGDGMAIISSLGSF----- 761

  Fly  1380 TGELRAKTQLNRKNRANYDIILVARDAGNPPFESLRLLSVSIVDANEN--------------RPE 1430
                      :|:.|..|.|.:|.:|:|.||......|:::|.|.|:|              |.:
Mosquito   762 ----------DREYRKQYTIPIVIKDSGTPPLTGTSTLTITIGDLNDNIMQPGSKEVIVYNYRGQ 816

  Fly  1431 FPD-------------------------ASNPYKVSINENSG-----RDVKIGHIQAASR---SK 1462
            .||                         |.|| :..:::.||     |..:.|..:...:   .|
Mosquito   817 APDTPIGRVFVNDLDDWDTSDKLFYWDEAENP-RFKLDDKSGMVTMRRGAREGRYKLRFKIYDRK 880

  Fly  1463 HNRDIFYYM-------------------LLGNEDGAF------------------YVDKLTG--- 1487
            |.::.:..|                   |:|..|..|                  :.|||..
Mosquito   881 HAQESYANMSIVVKHISYEAIVNSGSIRLIGITDEDFIRIWNYRTQNIFRSKLERFRDKLAELLN 945

  Fly  1488 ------DIYTNKSLDREE--TD----VYTLYILASIKAD----LHISE-EERASFSIKTLNRDNT 1535
                  ||::.:..||..  ||    |:..|...:::.:    ||..| |:....:|..:|.|..
Mosquito   946 VDVKNVDIFSVQMKDRSVPLTDVRFAVHGAYFYKAVQLNGVILLHKEEIEQEVGINITMVNVDEC 1010

  Fly  1536 VAKVA------ITVLDVNDNPPVFEKPIYYAGVNAN--AKMGAAITLVNATDADQGKNAKIEFMI 1592
            :.:.|      .::::|..||.:         ||||  |.:|..|            |:..| .|
Mosquito  1011 LLENADCAGSCTSIIEVQSNPCL---------VNANKTALVGVQI------------NSTAE-CI 1053

  Fly  1593 VASNLYK 1599
            .:|.:||
Mosquito  1054 CSSRVYK 1060

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad87A	NP_731649.2	Cadherin_repeat	33..128	CDD:206637
		Cadherin_repeat	136..240	CDD:206637
		Cadherin_repeat	248..353	CDD:206637
		Cadherin_repeat	362..468	CDD:206637
		Cadherin_repeat	476..>533	CDD:206637
		CA_like	<627..667	CDD:481204	3/11 (27%)
		CA	692..772	CDD:214520	20/79 (25%)
		Cadherin_repeat	778..873	CDD:206637	31/106 (29%)
		Cadherin_repeat	882..994	CDD:206637	28/127 (22%)
		Cadherin_repeat	1015..1099	CDD:206637	23/102 (23%)
		Cadherin_repeat	1108..1207	CDD:206637	28/100 (28%)
		Cadherin_repeat	1215..1314	CDD:206637	11/98 (11%)
		Cadherin_repeat	1327..1427	CDD:206637	19/104 (18%)
		Cadherin_repeat	1437..1549	CDD:206637	32/182 (18%)
		Cadherin_repeat	1557..1662	CDD:206637	13/45 (29%)
LOC1279112	XP_061509480.1	None