Protein Alignment Cad87A and LOC1279108

DIOPT Version :10

• Sequence 1: NP_731649.2
• Gene: Cad87A / 41441
• FlyBaseID: FBgn0037963
• Length: 1975
• Species: Drosophila melanogaster
• Sequence 2: XP_061509473.1
• Gene: LOC1279108 / 1279108
• VectorBaseID: AGAMI1_000307
• Length: 2873
• Species: Anopheles gambiae
• Alignment Length: 2091
• Identity: 426/2091 - (20%)
• Similarity: 719/2091 - (34%)
• Gaps: 657/2091 - (31%)

  Fly   122 ILDLNDNPPEFQNTPYEADVNEDAAVGTTIFDKITVKDRDIVGESLDLKCLPQQQSPEAC----- 181
            :|.|:|:|            ||.||:....|         ::|.|:.....|.....::|
Mosquito  1112 LLPLSDDP------------NELAALTPAHF---------LIGTSMFAVPEPDYTQLKSCTLDDL 1155

  Fly   182 RKFRLHIIKRDATILEAAVVLNDTLNYNQRMVYHFQIEATDGPHKTQTTFEARVKDVQDKPPVFQ 246
            :|::|.:    ..||:...::.|.|..       |.: .|:..:......:..|.|..|.|..|:
Mosquito  1156 QKWQLLV----QLILQLIGIIVDPLQI-------FWV-LTNSTYLVTKFIKTGVADKNDYPLFFE 1208

  Fly   247 GSLSTV-IDEDSPINTLVLTVHARDGDTGEPRKIVYDLRT-NPNDYFLLDAQTGELRTAKPLDRE 309
            ..:..| |||:..||...|.|..:  ..||...:.|.:.: |..:.|.:...||.|..||.||.|
Mosquito  1209 KVIYEVDIDENVEINHNFLNVSTK--THGEVSGVRYKISSGNIGNVFAIHNTTGALYVAKALDYE 1271

  Fly   310 ALEDSTGIISLVIRARELVNGVPSDDPLTSATAKATVTIRDVNDSPPVFNHKEYSVSLLENTLPG 374
            .::      ...:|...|       |..........:.:|||||:||||....|...:.|....|
Mosquito  1272 KIK------KYELRLTAL-------DNFKENYTTVLINVRDVNDNPPVFEKSSYRTQITEEDDRG 1323

  Fly   375 TP-LALDMSVSDADV-------------GI------NSKFALRLDDVSG-VFDVEPKLVTGYSQV 418
            .| ..|.::.|||||             ||      ||.|  .::..:| :|.::|
Mosquito  1324 LPKRVLRVTASDADVERPNNIIYFLTGPGIDIENPSNSNF--DINKATGEIFVLKP--------- 1377

  Fly   419 NIRVANGTLDYENPNQRKFIVLVVAEETDTNPRLSSTATITVSVLDANDNKPVFEQESYSASVSE 483
                    |:.:.|:.|......|..:.:....|.....:.:::.|.|||.|.|.......:|:|
Mosquito  1378 --------LNRDPPHGRASWKFTVFAQDEGGEGLVGFTEVQINLKDVNDNAPQFTNGIAYGNVTE 1434

  Fly   484 AALPGQYIATITARDVDSGSYG-DSGIRYSL------SGTGAELFHVNEQTGVISLANCHDNGES 541
            ....|.::.||.|.|.|..:.| ::.|.||:      ..||..:|.:|..||:|:...|
Mosquito  1435 NGTIGMHVMTIKAEDYDDINEGTNAKIIYSIEKNVIQEDTGLPIFDINPATGLITTVVC------ 1493

  Fly   542 NRRERRDLNEDEHVEEDDGEGHLEMLSMEAATREIGTEPTVQYTLITQAPEEQASSVPLPAPVPH 606
                                                                             
Mosquito  1494 ----------------------------------------------------------------- 1493

  Fly   607 AAPSGVPAATANDDKAPQTCLDYESETTYFLSYKATDD---NGRGSASVVSLRISVTDANDSPPV 668
                               |||.|....|.|...|||.   .|.|:||     |.|.|.||.||.
Mosquito  1494 -------------------CLDREKTPDYSLQIVATDGGGLKGTGTAS-----IKVKDLNDMPPR 1534

  Fly   669 CESPLYRASVDE--GAVVFDSPLI-VKARDADTMSRISYRI-----RGSEQVESIFDIDRETGQI 725
            .....:...|:|  |:|:.::|:: |...|.|.::...|:|     .|:::...:.:.| .||.:
Mosquito  1535 FTKDEWLVEVEETDGSVLPEAPILTVTVNDDDEINNFQYKIIESSGYGADKFAMVKNAD-GTGSL 1598

  Fly   726 -IIRPNATLDVTNLNSDQLIFAVEANDGL------FTAHCGVNITVRDVNNHVPNFEQQSYSAVV 783
             :::|....|...:|..:....|..||.:      ...|..|.:.::|:|::.|.|::....|.|
Mosquito  1599 KVVQPLDYEDPMQINGFRFRIQVIDNDDIDESDKYHVDHSWVIVKLKDINDNTPRFKKPHIEAAV 1663

  Fly   784 EENSEIGTSVERVHATDLDTGKNAELRYRIQQGSFD---DFGIVETTGEVFVSRKLDFDRRNTYQ 845
            .||:::|.::....|.|:|.|..:::.|.|.:.: |   .|.| :..|.|.:.|:||.:....:.
Mosquito  1664 YENADVGKNLGTFKAVDIDKGGKSKITYSINRAT-DRKRQFAI-DQEGMVTIQRELDREAMAKHS 1726

  Fly   846 LQIQASDQGTPSLTGTATLTINVQNSNDKDPYFVPATQHAEVRAD-APPGQLVYTLIALDPDVAN 909
            |:|.|:|.|.|..|..|.||:.|::.||..|.|  |..:..:..: :||.:
Mosquito  1727 LEILATDDGVPPRTAFAILTVLVKDINDNAPVF--AEDYRPILLENSPPSK-------------- 1775

  Fly   910 HNALEFAGTDDITAIDK----EGKELPHY--------DQFKEYFKISRNGK------VSVNKQLD 956
                    |.:|:|:||    ||...|..        |..:.:||:.::.|      :|.....|
Mosquito  1776 --------TIEISAVDKDDRLEGNGAPFQFRMDPDADDVIRTFFKVEQSNKGDGMAIISSLGSFD 1832

  Fly   957 RNLFAVMRINVLVTDSTAPNVQQGRGLLIIQIIDVNKNPPRFNAPWSVEQPQIKLQMV------- 1014
            |.......|.:::.||..| .|.|...|.|.|.|:|.|         :.||..|..:|
Mosquito  1833 REYRKQYTIPIVIKDSGTP-PQTGTSTLTITIGDLNDN---------IMQPGSKEVIVYNYQGQA 1887

  Fly  1015 EEQPVGTVLTTLQANDEDSS--IGEFNISDNDYFAINQTSGMI----------YTIARLDYE--- 1064
            .:.|:|.|... ..:|.|:|  :..::.::|..|.::..|||:          |.:....|:
Mosquito  1888 PDTPIGRVFVN-DLDDWDTSDKLFYWDETENPRFKLDDKSGMVSMRRGAREGRYKLRFKIYDRKH 1951

  Fly  1065 ----------VVKEVKFQVTVSDTGVPALTATADVVVDIINLNDNDPKFSQSDYYFNVTENSPRG 1119
                      |||.:.::..|:...:..:..|.:..:.|.|....:...|:.:.:        |.
Mosquito  1952 AQESYANMSIVVKHISYEAIVNSGSIRLIGVTDEDFIRIWNYRTQNIFRSKLERF--------RD 2008

  Fly  1120 TVAGKVEAHDGDVGVFG--------EITYTLIGENNKYFSIDAYTGNVMVANSSILDREQIKE-- 1174
            .:|..:.....:|.||.        .:|......:..||........|:     :|.:|:|::
Mosquito  2009 KLAELLNVDVKNVDVFSVQMKDRSVPLTDVRFAVHGAYFYKAVQLNGVI-----LLHKEEIEQEV 2068

  Fly  1175 -LTLSVVAQDKA---PAAVQKSATATIHI--NILDVNDNAPVFTRDVYNST---VAENAAYQPPA 1230
             :.:::|..|:.   .|....|.|:.|.:  |...||.|.........|||   |..:..|:
Mosquito  2069 GINITMVNVDECLLENADCAGSCTSIIEVQSNPCLVNANKTAMVGVQINSTAECVCSSREYK--- 2130

  Fly  1231 ALLQVQAIDQDEGLYGDVRYIITAGNEMGLFKLDAQSGIVYPAQSLSGKHGAYELTISARDTQGS 1295
               |.|.......|.|        |.     ..|::|||  ......|..|.....: .|..:||
Mosquito  2131 ---QQQTCKSHPCLNG--------GR-----CTDSKSGI--KCSCPPGYTGPRCQQV-VRSFRGS 2176

  Fly  1296 G-----TMESTTKAIITVLRVNRHKPEFVIPALSNATIEIPGDIVQPDYLLLTVRAMDNDTEENG 1355
            |     .::...|:.|:| .:...||:        ..|...|.|..|         .::||.:..
Mosquito  2177 GWAWYPPLDMCDKSHISV-EIITTKPD--------GLIFYNGPITPP---------KEDDTSKQL 2223

  Fly  1356 KVSYHLQVNNRNEQQTGEFKIDEVTG--ELRAKTQLNRKNRANYDIILVARDAGNPPFESLRLL- 1417
            .....|::    ||....|.||..:|  |||..|:| ..|...:..|.:..|.     |.::::
Mosquito  2224 SDFIALEL----EQGYPRFLIDYGSGTLELRIATKL-PLNDGEWHRIDLFWDT-----EQVKMVV 2278

  Fly  1418 ----SVSIVDANE-NRPEFPDAS----------NPYKVSINENSGRDVKIGHI------------ 1455
                :..|.:.:: |..||.|.:          |.|   :|.|:  .::||.:
Mosquito  2279 DFCKTAEITETDDGNLVEFIDHTCQALGKVPQFNEY---LNLNT--PLQIGGVFRDKFDYTYSRW 2338

  Fly  1456 ---------QAASRS-KHN---RDIFYYML-LGNEDGAFYVDKL--------------------- 1485
                     :...|: |||   .|:.:..| .|:..|..|..::
Mosquito  2339 QYMPVGVDFEGCIRNFKHNGILNDLSHPGLSKGSAPGCLYTQEVCDLNPQVARCLEHGKCVGSYV 2403

  Fly  1486 ----------TGDIYTNKSLDRE----ETDVYTLYILASIKAD-------------------LHI 1517
                      ||   |..||...    :|..|..|.| |.:.|                   ..|
Mosquito  2404 EAKCECNPGWTG---TYCSLPTTPTTFKTHSYVKYAL-SFEPDKFTTQIQLRFRTRETYGVLFRI 2464

  Fly  1518 SEEERASFSIKTLNRDNTV-------------AKVAITVLDVNDNPPVFEKPIYYAGVNANAKMG 1569
            |::....:.|..| :|..|             .:||:|.::|:|......|...|         |
Mosquito  2465 SDQHMREYGIIEL-KDAKVYFRYSLNTGQAEEQEVALTAVEVDDGQWHVVKVQRY---------G 2519

  Fly  1570 AAITLVNATDADQGKNAKIEFMI---------VASNLYKFGATKSTGSIVPSPFAISQDGRISAN 1625
            :|..|  ..|..:|.|....|..         ....:|..|..:.||              :...
Mosquito  2520 SAAIL--ELDGGEGANFNQSFSFDEHQWLSVDKQEGVYAGGKPEFTG--------------VKTY 2568

  Fly  1626 TIMAEYNQDRF-ELEIVARELEQPQSSASTKVNIWVFDGTQLVRVILSRPPEEVYQEQEEIIAEL 1689
            .:.::|.:... ::.:..:.|..|.::          :|||..:..:::
Mosquito  2569 DVKSDYQKSCIDDIRLDGKSLPLPPAT----------NGTQWGQATMAK---------------- 2607

  Fly  1690 RNATQHRIIVDEIRFHLDSIGRIRMDWCDLYFHAVDPQTQQ---------IAPVDEILKDIDRN- 1744
                       :|..:..|....:..:|...|..||...:.         |:|..:..  ||||
Mosquito  2608 -----------DIDRYCSSNNPCQNAYCPDPFECVDLWNKYECACGDGMIISPEGKTC--IDRNE 2659

  Fly  1745 -YDYLKDYYAGFAIENVVP--AYIAIVQDEF-----------------DLAVAGLVA--LVIVLF 1787
             .||  ....|....|..|  .|..|..|.:                 ..|:|.::|  |:|::|
Mosquito  2660 CLDY--PCLNGGTCINQEPRLKYKCICPDSYWGESCEFLKERQALKFSTSALAAVIACLLLIIIF 2722

  Fly  1788 VGVISFIVLCCCLKHWNLSVPVETRRKEALIKKQIIEDLNTTENPLWI------EQKLKLYEEQE 1846
            :    |:...|            :||:.|..||:.:...:..||.:..      |..:..::.:.
Mosquito  2723 L----FVYFYC------------SRRRSANFKKKPVTKDDIRENIINYCDEGGGENDMTAFDMKT 2771

  Fly  1847 LTMQVFSEPDHISNSEAPGHLDHRSSLEQVHHVGQT----------VDNTYATIQPRNNQNRLTG 1901
            |.:.:...|:.:.:...|...|.....:||  ||:.          ||...|:....:.:|....
Mosquito  2772 LKIPIGPLPELVQHKAPPVRPDIAVVSDQV--VGKVDVFLDDRKRRVDIDSASGPFDDLRNYAYE 2834

  Fly  1902 GGGAGGGSMRS 1912
            |.|:..||:.|
Mosquito  2835 GCGSTSGSLSS 2845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad87A	NP_731649.2	Cadherin_repeat	33..128	CDD:206637	2/5 (40%)
		Cadherin_repeat	136..240	CDD:206637	19/108 (18%)
		Cadherin_repeat	248..353	CDD:206637	27/106 (25%)
		Cadherin_repeat	362..468	CDD:206637	25/126 (20%)
		Cadherin_repeat	476..>533	CDD:206637	19/63 (30%)
		CA_like	<627..667	CDD:481204	17/42 (40%)
		CA	692..772	CDD:214520	18/91 (20%)
		Cadherin_repeat	778..873	CDD:206637	30/97 (31%)
		Cadherin_repeat	882..994	CDD:206637	28/130 (22%)
		Cadherin_repeat	1015..1099	CDD:206637	20/108 (19%)
		Cadherin_repeat	1108..1207	CDD:206637	21/114 (18%)
		Cadherin_repeat	1215..1314	CDD:206637	23/106 (22%)
		Cadherin_repeat	1327..1427	CDD:206637	23/107 (21%)
		Cadherin_repeat	1437..1549	CDD:206637	35/204 (17%)
		Cadherin_repeat	1557..1662	CDD:206637	15/114 (13%)
LOC1279108	XP_061509473.1	None