Protein Alignment Cad87A and LOC1279098

DIOPT Version :10

• Sequence 1: NP_731649.2
• Gene: Cad87A / 41441
• FlyBaseID: FBgn0037963
• Length: 1975
• Species: Drosophila melanogaster
• Sequence 2: XP_061509423.1
• Gene: LOC1279098 / 1279098
• VectorBaseID: AGAMI1_012222
• Length: 1649
• Species: Anopheles gambiae
• Alignment Length: 2013
• Identity: 404/2013 - (20%)
• Similarity: 657/2013 - (32%)
• Gaps: 714/2013 - (35%)

  Fly   191 RDATILEAAVVLNDTLNYNQRMVYHFQIEATDGPHKTQTTFEARVKDVQDKPPVFQ-GSLSTVI- 253
            |:||   .|:.:...|:|.:...|..::.|:|...:..||....|:|:.|.||||: .|..|.|
Mosquito    32 RNAT---GALYVAKALDYEKIKKYELRLTASDNFQENYTTVLINVRDLNDNPPVFEKSSYRTQIT 93

  Fly   254 -DEDSPINTLVLTVHARDGDTGEPRKIVYDLR------TNPND-YFLLDAQTGELRTAKPLDREA 310
             ::|..:...||.|.|.|.|...|..|:|.|.      .||:| ||.::..|||:...|||:|
Mosquito    94 EEDDRGLPKRVLRVTASDADVERPNNIIYFLTGAGIDIENPSDSYFDINKATGEIFVLKPLNR-- 156

  Fly   311 LEDSTGIISLVIRARELVNGVPSDDPLTSATAKATVTIRDVNDSPPVFNHKEYSVSLLENTLPGT 375
                                   |.|...|:.|.||..:|
Mosquito   157 -----------------------DPPHGRASWKFTVFAQD------------------------- 173

  Fly   376 PLALDMSVSDADVGINSKFALRLDDVSGVFDVEPKLVTGYSQVNIRVANGTLDYENPNQRKFIVL 440
                     :...|:                      .|:::|.|
Mosquito   174 ---------EGGEGL----------------------VGFTEVQI-------------------- 187

  Fly   441 VVAEETDTNPRLSSTATITVSVLDANDNKPVFEQESYSASVSEAALPGQYIATITARDVDSGSYG 505
                                ::.|.|||.|.|...:...:|:|....|:::.||.|:|.|..:.|
Mosquito   188 --------------------NLKDVNDNAPQFLNGTAYGNVTENGTIGKHVMTIKAKDYDDINEG 232

  Fly   506 -DSGIRYSL------SGTGAELFHVNEQTGVISLANCHDNGESNRRERRDLNEDEHVEEDDGEGH 563
             ::.|.||:      ..||..:|.:|..||:|:.|.|
Mosquito   233 TNAKIIYSIEKNAIQEDTGLPIFDINPDTGLITTAVC---------------------------- 269

  Fly   564 LEMLSMEAATREIGTEPTVQYTLITQAPEEQASSVPLPAPVPHAAPSGVPAATANDDKAPQTCLD 628
                                                                          |||
Mosquito   270 --------------------------------------------------------------CLD 272

  Fly   629 YESETTYFLSYKATDD---NGRGSASVVSLRISVTDANDSPPVCESPLYRASVDE--GAVVFDSP 688
            .|....|.|...|||.   .|.|:||     |.|.|.||.||......:...|:|  |:|:.::|
Mosquito   273 REKTPDYSLQIVATDGGGLKGTGTAS-----IKVKDLNDMPPRFTKDEWFVEVEETDGSVLPEAP 332

  Fly   689 LI-VKARDADTMSRISYRI-----RGSEQVESIFDIDRETGQI-IIRPNATLDVTNLNSDQLIFA 746
            :: |...|.|.::...|:|     .|:::...:.:.| .||.: :::|....|...:|..:....
Mosquito   333 ILTVTVNDDDEINNFQYKIIESSGYGADKFAMVKNAD-GTGSLKVVQPLDYEDPLQINGFRFRIQ 396

  Fly   747 VEANDGL------FTAHCGVNITVRDVNNHVPNFEQQSYSAVVEENSEIGTSVERVHATDLDTGK 805
            |..||.:      ...|..|.:.::|:|::.|.|::....|.|.||:::|..:....|.|:|.|.
Mosquito   397 VIDNDDIDESDKYHVDHSWVIVKLKDINDNTPRFKKPHIEAAVYENADVGKKLGTFKAVDIDKGG 461

  Fly   806 NAELRYRIQQGSFD---DFGIVETTGEVFVSRKLDFDRRNTYQLQIQASDQGTPSLTGTATLTIN 867
            .:::.|.|.:.: |   .|.| :..|.|.:.|:||.:....:.|:|.|:|.|.|..|..|.||:.
Mosquito   462 KSKITYSINRAT-DRKRQFAI-DQEGTVTIHRELDREAMAKHSLEILATDDGVPPRTAFAILTVL 524

  Fly   868 VQNSNDKDPYFVPATQHAEVRAD-APPGQLVYTLIALDPDVANHNALEFAGTDDITAIDK----E 927
            |::.||..|.|  |..:..:..: :||.:::                      :|:|:||    |
Mosquito   525 VKDINDNAPVF--AEDYRPILLENSPPSKII----------------------EISAVDKDDRLE 565

  Fly   928 GKELPHY--------DQFKEYFKISRNGK------VSVNKQLDRNLFAVMRINVLVTDSTAPNVQ 978
            |...|..        |..:..||:.::.|      :|.....||.......|.:::.||..| .|
Mosquito   566 GNGAPFQFRMDPDADDVIRTSFKVEQSNKGDGMAIISSLGSFDREYRKQYTIPIVIKDSGTP-PQ 629

  Fly   979 QGRGLLIIQIIDVNKNPPRFNAPWSVEQPQIKLQMV-------EEQPVGTVLTTLQANDEDSS-- 1034
            .|...|.|.|.|:|.|         :.||..|..:|       .:.|:|.|... ..:|.|:|
Mosquito   630 TGTSTLTITIGDLNDN---------IMQPGSKEVIVYNYQGQAPDTPIGRVFVN-DLDDWDTSDK 684

  Fly  1035 IGEFNISDNDYFAINQTSGMI----------YTIARLDYE-------------VVKEVKFQVTVS 1076
            :..::.::|..|.::.||||:          |.:....|:             |||.:.::..|:
Mosquito   685 LFYWDEAENPRFKLDDTSGMVTMRRGAREGRYKLRFKIYDRKHAQESYANMSVVVKHISYEAIVN 749

  Fly  1077 DTGVPALTATADVVVDIINLNDNDPKFSQSDYYFNVTENSPRGTVAGKVEAHDGDVGVFG----- 1136
            ...:.....|.:..:.|.|....:...|:.:.:        |..:|..:..|..:|.||.
Mosquito   750 SGSIRLTGITDEDFIRIWNYRTQNIFRSKLERF--------RDKLAELLNVHVKNVDVFSVQLKD 806

  Fly  1137 ------EITYTLIGENNKYFSIDAYTGNVMVANSSI-LDREQIKE---LTLSVVAQDKA---PAA 1188
                  ::.:.:.|         ||....:..|..| |.:|:|::   :.:::|..|:.   .|.
Mosquito   807 RSVPLIDVRFAVHG---------AYFYKAVQLNGLILLHKEEIEQEVGINITMVNVDECLLENAD 862

  Fly  1189 VQKSATATIHI--NILDVNDNAPVFTRDVYNST---VAENAAYQPPAALLQVQAIDQDEGLYGDV 1248
            ...|.|:.|.:  |...||.|.........|||   |..:..|:      |.|.......|.|
Mosquito   863 CAGSCTSIIEVQSNPCLVNANKTALVGVQINSTAECVCSSREYK------QQQTCKSHPCLNG-- 919

  Fly  1249 RYIITAGNEMGLFKLDAQSGIVYPAQSLSGKHGAYELTISARDTQGSG-----TMESTTKAIITV 1308
                  |.     ..|::|||  ....|.|..|.....: .|..:|||     .::...|:.|:|
Mosquito   920 ------GR-----CTDSKSGI--KCSCLPGYTGPRCQQV-VRSFRGSGWAWYPPLDMCDKSHISV 970

  Fly  1309 LRVNRHKPEFVIPALSNATIEIPGDIVQPDYLLLTVRAMDNDTEENGKVSYHLQVNNRNEQQTGE 1373
             .:...||:        ..|...|.|..|         .::||.:.......|::    ||....
Mosquito   971 -EIITTKPD--------GLIFYNGPITPP---------KEDDTSKQLSDFIALEL----EQGYPR 1013

  Fly  1374 FKIDEVTG--ELRAKTQ--LNRKNRANYDII-----------------LVARDAGNPPFESLRLL 1417
            |.||..:|  |||..|:  ||.......|:.                 :...|.||
Mosquito  1014 FLIDYGSGTLELRIATKHPLNDGEWHRIDLFWDTDQVKIVVDFCKTAEITEPDDGN--------- 1069

  Fly  1418 SVSIVD----ANENRPEFPDASNPYKVSINENSG-------RD-------------VKIGHIQAA 1458
            .|.|:|    |....|:|    |.|   :|.|:.       ||             |.:|.....
Mosquito  1070 LVEIIDHTCQALGKVPQF----NEY---LNLNTPLQIGGVFRDKFDYTYSRWQYMPVGVGFEGCI 1127

  Fly  1459 SRSKHNRDIFYYMLLGNEDGAFYVDKLTGDIYTNKSLDRE------------------------- 1498
            ...|||..::.....|...|:     ..|.:||.:..|..
Mosquito  1128 REFKHNGILYDLSHPGLSKGS-----APGCLYTQEVCDLNPQVARCLEHGKSVGSYVEAKCECNP 1187

  Fly  1499 ----------------ETDVYTLYILA------SIKADL------------HISEEERASFSI-- 1527
                            :|..|..|.|:      :.:..|            .||::....:.|
Mosquito  1188 GWTGTYCSLPTTPTTFKTHSYVKYALSFEPNKFTTQIQLRFRTRETYGELFRISDQHMREYGIIE 1252

  Fly  1528 ---------KTLNRDNT-VAKVAITVLDVNDNPPVFEKPIYYAGVNANAKMGAAITLVNATDADQ 1582
                     .:||.|.. ..:||:|.::|:|......|...|         |:|..|  ..|..:
Mosquito  1253 LKDAKVYFRYSLNTDQVEEQEVALTAVEVDDGQWHVVKVQRY---------GSAAIL--ELDGGE 1306

  Fly  1583 GKNAKIEFMI---------VASNLYKFGATKSTGSIVPSPFAISQDGRISANTIMAEYNQDRFEL 1638
            |.|....|..         ....:|..|..:.||              :....:.::|
Mosquito  1307 GANFNQSFSFDGHQWLSVDKQEGVYAGGKPEFTG--------------VKTYDVKSDY------- 1350

  Fly  1639 EIVARELEQPQSSASTKVNIWVFDGTQLVRVILSRPPEEVYQEQEEIIAELRNATQ--HRIIVDE 1701
                      |.|....:.   |||..     |..||             ..|.||  ...:..:
Mosquito  1351 ----------QKSCIDDIR---FDGKS-----LPLPP-------------ATNGTQWGQATMAKD 1384

  Fly  1702 IRFHLDSIGRIRMDWCDLYFHAVDPQTQQ---------IAPVDEILKDIDRN--YDY-------- 1747
            |..:..|....:..:|...|..||...:.         |:|..:..  ||||  .||
Mosquito  1385 IDRYCSSNNPCQNAYCPDPFECVDLWNKYECACGDGMIISPEGKTC--IDRNECLDYPCLNGGTC 1447

  Fly  1748 ------LK------DYYAGFAIENVVPAYIAIVQDEFDLAVAGLVALVIVLFVGVISFIVLCCCL 1800
                  ||      |.|.|.:.|.:..      :.....:.:.|.|::..|.:.:|...|...|
Mosquito  1448 INQEPRLKYKCICPDSYWGESCEFLKE------RQALKFSTSALAAVIACLLLIIILLFVYFSC- 1505

  Fly  1801 KHWNLSVPVETRRKEALIKKQIIEDLNTTENPLWI------EQKLKLYEEQELTMQVFSEPDHIS 1859
                      :||:.|...|:.....:..||.:..      |..:..::.:.|.:.:...|:.:.
Mosquito  1506 ----------SRRRSANFNKKPATKDDIRENIINYCDEGGGENDMTAFDMKTLKIPIGPLPELVQ 1560

  Fly  1860 NSEAPGHLDHRSSLEQVHHVGQT----------VDNTYATIQPRNNQNRLTGGGGAGGGSMRS 1912
            :...|...|.....:||  ||:.          ||...|:....:.:|....|.|:..||:.|
Mosquito  1561 HKAPPVRPDIAVVSDQV--VGKVDVFLDDRKRRVDIDSASGPFDDLRNYAYEGCGSTSGSLSS 1621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad87A	NP_731649.2	Cadherin_repeat	33..128	CDD:206637
		Cadherin_repeat	136..240	CDD:206637	13/48 (27%)
		Cadherin_repeat	248..353	CDD:206637	33/113 (29%)
		Cadherin_repeat	362..468	CDD:206637	6/105 (6%)
		Cadherin_repeat	476..>533	CDD:206637	19/63 (30%)
		CA_like	<627..667	CDD:481204	17/42 (40%)
		CA	692..772	CDD:214520	18/91 (20%)
		Cadherin_repeat	778..873	CDD:206637	30/97 (31%)
		Cadherin_repeat	882..994	CDD:206637	27/130 (21%)
		Cadherin_repeat	1015..1099	CDD:206637	21/108 (19%)
		Cadherin_repeat	1108..1207	CDD:206637	23/118 (19%)
		Cadherin_repeat	1215..1314	CDD:206637	24/106 (23%)
		Cadherin_repeat	1327..1427	CDD:206637	27/124 (22%)
		Cadherin_repeat	1437..1549	CDD:206637	31/202 (15%)
		Cadherin_repeat	1557..1662	CDD:206637	15/113 (13%)
LOC1279098	XP_061509423.1	None