DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Cad87A and pcdh19

DIOPT Version :10

Sequence 1:NP_731649.2 Gene:Cad87A / 41441 FlyBaseID:FBgn0037963 Length:1975 Species:Drosophila melanogaster
Sequence 2:XP_002938421.1 Gene:pcdh19 / 100494505 XenbaseID:XB-GENE-1113172 Length:1101 Species:Xenopus tropicalis


Alignment Length:806 Identity:212/806 - (26%)
Similarity:343/806 - (42%) Gaps:97/806 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   783 VEENSEIGTSVERVHATDLDTGKNAELR---YRIQQGSFDDFGIVETTGEVFVSRKLDFDR---- 840
            |||....||.:..|.....|.|...:.|   :|:...|......:..:|.:...:|:|.|.    
 Frog    35 VEEEQRAGTVIANVAKDAKDAGFVLDPRQPAFRVVSNSASHLVDINASGLLVTKQKIDRDMLCRQ 99

  Fly   841 --RNTYQLQIQASDQGTPSLTGTATLTINVQNSNDKDPYFVPATQHAEVRADAPPGQLVYTLIAL 903
              :....|::.::..      ....:.:.:::.||..|.|.......|:...|.||..:....|.
 Frog   100 IPKCVISLEVMSNSM------EICVIKVEIKDLNDNAPSFPTDQIDLEISETASPGTRIPLESAY 158

  Fly   904 DPDVANHNALEFAGTDDITAIDKEGKELPHYDQFKEYFKISRNGKVSVNKQLDRNLFAVMRINVL 968
            |||..|:.    ..|.:||..|..|.|:      |.....||..::.|.|.|||...:.....:.
 Frog   159 DPDSGNYG----VQTYEITPNDLFGLEI------KTRGDGSRFAELVVEKALDRETQSHYSYIIT 213

  Fly   969 VTDSTAPNVQQGRGLLIIQIIDVNKNPPRF-NAPWSVEQPQIKLQMVEEQPVGTVLTTLQANDED 1032
            ..|...|: ..|...|.|::||.|.|.|.| .|.::|..|       |...:.|::..|.|.|.|
 Frog   214 ALDGGDPS-NFGTVELNIKVIDSNDNNPMFEEAAYTVNVP-------ENSALNTMVIDLNATDPD 270

  Fly  1033 SSI-GEFNISDNDY--------FAINQTSGMIYTIARLDYEVVKEVKFQVTVSDTGVPALTATAD 1088
            ... ||...|.|.|        |.|:..:|:|.....:|||.....:..|...|.|..::.|...
 Frog   271 EGTNGEIVYSFNSYVSDKTRELFKIDPKTGVITVSGAIDYEEGHVYEIDVQAKDLGPNSIPAHCK 335

  Fly  1089 VVVDIINLNDNDP---KFSQSDYYFNVTENSPRGTVAGKVEAHDGDVGVFGEITYTLIGENNKYF 1150
            |.|:::::|||.|   ..|.:.....|:||:|.|.|...|...|.|.|:.|.:...|:|  :..|
 Frog   336 VTVNVLDMNDNVPVINLLSVNSEVVEVSENAPPGYVIALVRVSDKDSGINGRVLCKLLG--SVPF 398

  Fly  1151 SIDAYTGNVMVANSSILDREQIKELTLSVVAQDKAPAAVQKSATATIHINILDVNDNAPVFTRDV 1215
            .:..|.....:.....|||||..:..|::.|:|....::|.:.:.|:.|.  |.|||.|.|::..
 Frog   399 RLQEYESFSTILVDGRLDREQRDQYNLTIQAKDSGNPSLQSTKSFTVRIT--DENDNHPHFSKTF 461

  Fly  1216 YNSTVAENAAYQPPAALLQVQAIDQDEGLYGDVRYIITAG--NEMGLF---KLDAQSGIVYPAQS 1275
            |...|:||..  |.|.||.|.|.|.|.||.|.|.|.:...  .:|.:|   .::..||.:|..:|
 Frog   462 YQVIVSENNT--PGAYLLSVSARDPDLGLNGSVSYQLVPSQVRDMPVFTYVSINPTSGDIYALRS 524

  Fly  1276 LSGKH-GAYELTISARDTQGSGTMESTTKAIITVLRVNRHKPEFVIPALSNATIE--IPGDIVQP 1337
            .:.:. .|:|..|.|:| .|:.:::|.....:.|:.||.:.|....|.|.|.|.|  ||.: ...
 Frog   525 FNHEQTKAFEFKILAKD-GGNPSLQSNVTVRVIVVDVNDNTPVITAPPLVNGTSEVYIPRN-AGV 587

  Fly  1338 DYLLLTVRAMDNDTEENGKVSYHLQVNNRNEQQTGEFKIDEVTGELRAKTQLNRKNRANYDIILV 1402
            .||:..|:|.|.|..|||::||.:...:|     |.|:||:|.||:|........::..|::|:|
 Frog   588 GYLVTMVKADDYDEGENGRLSYEISEGDR-----GFFEIDQVNGEIRTTRTFGENSKTTYELIVV 647

  Fly  1403 ARDAGNPPFESLRLLSVSI---VDANENRPEFPDASNPYKVSINENSGRDVKIGHIQA------- 1457
            |.|.|.|...:..|:.:.:   :||.|:..           |:|.:....:.:|.|.|       
 Frog   648 AHDHGKPSLSASALILIYLSPTLDAQESIG-----------SVNLSLIFIIALGSIAAILFVTMI 701

  Fly  1458 --ASRSKH-NRDIFYY------MLLGNEDGAFYVDKLTGDIYTNKSLDREETDVYTLYILASIKA 1513
              |.:.|. |::|..|      ...|::..:....|::.:.......|.||||...:...:|:.:
 Frog   702 FVAVKCKRDNKEIRTYNCRIAEYSYGHQKKSNKKKKISKNDIRLVPRDVEETDKMNVVSCSSLTS 766

  Fly  1514 DLHISEEERASFSIKTLNRDNTVAKV 1539
            .|:..:..:.:..:.....|:|...|
 Frog   767 SLNYFDYHQQTLPLGCRRSDSTFLNV 792

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cad87ANP_731649.2 Cadherin_repeat 33..128 CDD:206637
Cadherin_repeat 136..240 CDD:206637
Cadherin_repeat 248..353 CDD:206637
Cadherin_repeat 362..468 CDD:206637
Cadherin_repeat 476..>533 CDD:206637
CA_like <627..667 CDD:481204
CA 692..772 CDD:214520
Cadherin_repeat 778..873 CDD:206637 16/98 (16%)
Cadherin_repeat 882..994 CDD:206637 31/111 (28%)
Cadherin_repeat 1015..1099 CDD:206637 25/92 (27%)
Cadherin_repeat 1108..1207 CDD:206637 28/98 (29%)
Cadherin_repeat 1215..1314 CDD:206637 33/104 (32%)
Cadherin_repeat 1327..1427 CDD:206637 34/104 (33%)
Cadherin_repeat 1437..1549 CDD:206637 22/119 (18%)
Cadherin_repeat 1557..1662 CDD:206637
pcdh19XP_002938421.1 Cadherin_2 33..110 CDD:462413 16/74 (22%)
Cadherin_repeat 140..238 CDD:206637 31/108 (29%)
Cadherin_repeat 247..346 CDD:206637 27/105 (26%)
Cadherin_repeat 359..453 CDD:206637 28/97 (29%)
Cadherin_repeat 462..563 CDD:206637 33/103 (32%)
Cadherin_repeat 578..666 CDD:206637 31/93 (33%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.