DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment mthl5 and Adgrf4

DIOPT Version :9

Sequence 1:NP_001287291.1 Gene:mthl5 / 41438 FlyBaseID:FBgn0037960 Length:497 Species:Drosophila melanogaster
Sequence 2:NP_001276428.1 Gene:Adgrf4 / 78249 MGIID:1925499 Length:698 Species:Mus musculus


Alignment Length:300 Identity:73/300 - (24%)
Similarity:118/300 - (39%) Gaps:87/300 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   197 NICLARKEIKWSDSNFLLRKILNPI-FHGI-----SLVILLVI-AIIYFILPTLSRDLVGNIVTT 254
            :|.::.|.:|        ..|||.| |.|:     |||:.||| ||::      ||.:|..|...
Mouse   392 SILMSSKPVK--------NTILNHITFIGLSISIFSLVLCLVIEAIVW------SRVVVTEISYM 442

  Fly   255 IAMCLMVSQAADLVRIFTELTSHVSFI----------------VADIILC-FSLLAAFFW----- 297
            ..:|: |:.|..|      ||::|.||                ||...|| |..|:.|||     
Mouse   443 RHVCI-VNIAVSL------LTANVWFIIGSNFSANVQEDHKWCVAVTFLCHFFFLSLFFWMLFKA 500

  Fly   298 -LNSFGFYIWKTFRSRNVFLRVTDGRKYCYYSAYAWGCTATMAALAVFAHFFLDAESYKQEHMVG 361
             |..:|..:        ||.|:...|......|..:||...:|.:.|..  ....|.|.::... 
Mouse   501 LLIVYGILV--------VFRRMMKSRMMAIGFAIGYGCPLVIAVITVTV--TEPGEGYTRKDAC- 554

  Fly   362 EQETIGWL------GICIFFAPIACTILVNIFFYV-----TTRKLI-NRRTVYGRIAHKLKANFI 414
                  ||      .:..|..|....:.||:...:     |.|.|| :.::....|..::..|  
Mouse   555 ------WLNWNQTKALFAFAIPALAIVAVNLLVVLAVAINTQRPLIGSSKSQDMAIVFRISKN-- 611

  Fly   415 MFSLMLLVMSIAWLFLIMSWLQMEGLLYAHIV---VNALQ 451
             .:::..::.:.|.|.:.:.|:...|:: ||:   :||.|
Mouse   612 -VAILTPLLGLTWGFGLTTLLEGVHLVF-HIIFALLNAFQ 649

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl5NP_001287291.1 7tm_4 212..451 CDD:304433 69/283 (24%)
Adgrf4NP_001276428.1 GPS 351..394 CDD:366827 0/1 (0%)
7tm_GPCRs 402..669 CDD:391938 69/281 (25%)
TM helix 1 405..429 CDD:341315 11/23 (48%)
TM helix 2 444..465 CDD:341315 9/27 (33%)
TM helix 3 479..501 CDD:341315 9/21 (43%)
TM helix 4 522..538 CDD:341315 4/15 (27%)
TM helix 5 560..583 CDD:341315 4/22 (18%)
TM helix 6 606..631 CDD:341315 3/27 (11%)
TM helix 7 636..661 CDD:341315 5/14 (36%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.