DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl5 and Adgrf1

DIOPT Version :9

Sequence 1:NP_001287291.1 Gene:mthl5 / 41438 FlyBaseID:FBgn0037960 Length:497 Species:Drosophila melanogaster
Sequence 2:XP_006525183.1 Gene:Adgrf1 / 77596 MGIID:1924846 Length:927 Species:Mus musculus


Alignment Length:345 Identity:71/345 - (20%)
Similarity:125/345 - (36%) Gaps:89/345 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   204 EIKWSDS-----NFLLRKILNPIFHGISLVILL----------VIAIIYFILPTLSRDLVGNIVT 253
            :::||::     |..|..:|....|..|..:|:          |:..|.:|..::|       :.
Mouse   558 QLQWSNAGCQLVNETLDTVLCRCSHLTSFSMLMSPFVPSSVVPVVKWITYIGLSIS-------IA 615

  Fly   254 TIAMCLMV----------SQAA-----DLVRIFTE-LTSHVSFIVADII--------LC------ 288
            ::.:||::          ||.:     .||.|... |.:.|.||:|..:        :|      
Mouse   616 SLILCLIIESLFWKQTKRSQTSYTRNICLVNIAVSLLIADVWFIIAATVDPSVSPSGVCVAAVFF 680

  Fly   289 --FSLLAAFFWLNSFGFYIWKTFRSRNVFLRVTDGRKYCYYSAYAWGC--TATMAALAVFAHFFL 349
              |..||.|||:...|..:  .:|...||..:.............:||  ..::..|||..    
Mouse   681 THFFYLAVFFWMLVLGILL--AYRIILVFHHMALTTMMAIGFCLGYGCPLLISIITLAVTQ---- 739

  Fly   350 DAESYKQEHMVGEQETIGWLG-------ICIFFAPIACTILVNIFFYVTTRKLINRRTVYGRIAH 407
            .:.|||       :..:.||.       :..|..|....:.||:...:...:.:.|..|..|:..
Mouse   740 PSNSYK-------RNDVCWLNWSDKSKPLLAFVVPALTIVAVNLVVVLLVLRKLWRPAVGERLNQ 797

  Fly   408 KLKANFIMFSLMLLVMS----IAWLFLIMSWLQMEGLLYAHI---VVNALQTPLLLYICVLRQRH 465
            ..||..|.....|||::    :.|.|.|.:......|.: |:   ::||.|...:....:|....
Mouse   798 DDKATAIRMGKSLLVLTPLLGLTWGFGIGTMANSHNLAW-HVLFALLNAFQGFFIFCFGILLDTK 861

  Fly   466 VTFLLKKTCCYNEPPSANDW 485
            :..||.     |:..:.:.|
Mouse   862 LRQLLS-----NKLTTLSSW 876

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl5NP_001287291.1 7tm_4 212..451 CDD:304433 62/296 (21%)
Adgrf1XP_006525183.1 SEA 172..258 CDD:366610
GPS 549..590 CDD:197639 7/31 (23%)
7tm_GPCRs 603..866 CDD:391938 58/283 (20%)
TM helix 1 603..626 CDD:341315 5/29 (17%)
TM helix 2 641..663 CDD:341315 8/21 (38%)
TM helix 3 675..702 CDD:341315 7/28 (25%)
TM helix 4 716..736 CDD:341315 2/19 (11%)
TM helix 5 757..786 CDD:341315 4/28 (14%)
TM helix 6 803..829 CDD:341315 7/25 (28%)
TM helix 7 834..859 CDD:341315 6/25 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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