DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl5 and adgrd2

DIOPT Version :9

Sequence 1:NP_001287291.1 Gene:mthl5 / 41438 FlyBaseID:FBgn0037960 Length:497 Species:Drosophila melanogaster
Sequence 2:XP_021334184.1 Gene:adgrd2 / 571770 ZFINID:ZDB-GENE-081104-190 Length:1145 Species:Danio rerio


Alignment Length:262 Identity:54/262 - (20%)
Similarity:108/262 - (41%) Gaps:42/262 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   216 KILNPIFHGISLVILLVIAIIYFIL-------PTLSRDLVGNIVTTIAMCLMVSQAADLVRIFTE 273
            :||:.|...:||..|:...|::..:       .|:.::|:..::....:.::...||.       
Zfish   796 QILSLIGSAVSLCALIFTFILFVAVGVPKSDRTTVHKNLMAALIVAQFLLILSDWAAG------- 853

  Fly   274 LTSHVSFIVADIILCFSLLAAFFWLNSFGFYIWKTFRSRNVFLRVTDGRKYCYYSAYAWGCTATM 338
             :....::|..::..| .|::|.|:...|..:|    |:.|.:.:::.|:...|....||....:
Zfish   854 -SQEACWLVTALLHLF-FLSSFCWMLVEGLLLW----SKVVSVNISEDRRMKMYYVLGWGLPVVI 912

  Fly   339 AALAVFAHFFLDAESYKQEHMVGEQETIGWLGICIFFAPIACTILVN--IFFYV--TTRKLINRR 399
            .|:.:.|  .||....:|...:..|.::.|    .|..|:...:.||  :.|.|  .|.....||
Zfish   913 VAVTLVA--TLDQYKAQQHCWLNLQSSVIW----AFAGPVLFVLAVNAVVLFRVVLVTVSSARRR 971

  Fly   400 TVYGRIAHKLKANFIMFS--------LMLLVMSIAWLFLIMSWLQMEGLLYAHIVVNALQTPLLL 456
            ......:...|.:.:..:        ::|.|:.:.||..::..|. :.:.|..|.:||.|.   |
Zfish   972 AKMLTPSSDSKLHTLDLTWAATRPVLILLPVLGLTWLCGVLVHLS-DVMAYLFITLNAFQG---L 1032

  Fly   457 YI 458
            ||
Zfish  1033 YI 1034

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl5NP_001287291.1 7tm_4 212..451 CDD:304433 50/253 (20%)
adgrd2XP_021334184.1 LamG 204..402 CDD:328935
GPS 735..779 CDD:307782
7tmB2_GPR144 792..1054 CDD:320383 54/262 (21%)
TM helix 1 794..819 CDD:320383 7/22 (32%)
TM helix 2 828..850 CDD:320383 2/21 (10%)
TM helix 3 859..886 CDD:320383 7/31 (23%)
TM helix 4 898..918 CDD:320383 4/19 (21%)
TM helix 5 935..964 CDD:320383 8/32 (25%)
TM helix 6 988..1015 CDD:320383 4/26 (15%)
TM helix 7 1017..1042 CDD:320383 8/21 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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