DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl5 and adgrl1a

DIOPT Version :9

Sequence 1:NP_001287291.1 Gene:mthl5 / 41438 FlyBaseID:FBgn0037960 Length:497 Species:Drosophila melanogaster
Sequence 2:XP_021330394.1 Gene:adgrl1a / 562531 ZFINID:ZDB-GENE-131127-267 Length:1524 Species:Danio rerio


Alignment Length:276 Identity:64/276 - (23%)
Similarity:108/276 - (39%) Gaps:52/276 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   225 ISLVILLVIAIIYFILPTLSRDLVGNIVTTIAMCLMVSQAADLVRIFTELTSHVSFIVADIILCF 289
            ||||.|.:....:..|..|..|. ..|...:.:.|.:::...|:.| .:...|::..:...:|.|
Zfish   862 ISLVCLAICISTFCFLRGLQTDR-NTIHKNLCINLFIAELLFLIGI-DKTQYHIACPIFAGLLHF 924

  Fly   290 SLLAAFFWLNSFGFYIWKTFRSRNVFLRVTDGRKYCYYSAYAWGCTATMAALAVFAHFFLDAESY 354
            ..||||.|:...|..::  .....||......:||.|...|.:      .||.|.....:|..||
Zfish   925 FFLAAFSWMCLEGIQLY--LMLVEVFESEYSRKKYYYLCGYCF------PALVVGISAAIDYRSY 981

  Fly   355 KQEHMVGEQETIGWLG-----ICIFFAPIACTILVN-IFFYVTTRKLINRRTVYGRIAHKLKANF 413
                  |.::.. ||.     |..|..|::..|::| :|..:|..|:|...:.....:.:|. |.
Zfish   982 ------GTKKAC-WLRVDNYFIWSFIGPVSFIIMLNLVFLMITLHKMIRNSSALKPDSSRLD-NI 1038

  Fly   414 IMFSL----MLLVMSIAWLFLIMSWLQMEGLL----------YAHIVVNALQTP-LLLYICVLRQ 463
            ..::|    :|.::.:.|.|         |||          |.....||.|.. :.::.|.|::
Zfish  1039 KSWALGAIALLFLLGLTWAF---------GLLFINENTVIMAYLFTTFNAFQGMFIFIFHCALQK 1094

  Fly   464 R-HVTF---LLKKTCC 475
            : |..:   |....||
Zfish  1095 KVHKEYSKCLRHSYCC 1110

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl5NP_001287291.1 7tm_4 212..451 CDD:304433 57/245 (23%)
adgrl1aXP_021330394.1 Gal_Lectin 48..128 CDD:307994
OLF 142..398 CDD:321983
HormR 474..535 CDD:214468
GAIN 545..765 CDD:318649
GPS 789..836 CDD:197639
7tmB2_Latrophilin-1 849..1106 CDD:320673 62/270 (23%)
TM helix 1 851..876 CDD:320673 5/13 (38%)
TM helix 2 885..907 CDD:320673 4/22 (18%)
TM helix 3 916..943 CDD:320673 8/28 (29%)
TM helix 4 955..975 CDD:320673 7/25 (28%)
TM helix 5 992..1021 CDD:320673 7/28 (25%)
TM helix 6 1037..1064 CDD:320673 8/35 (23%)
TM helix 7 1068..1093 CDD:320673 5/24 (21%)
Latrophilin 1105..1524 CDD:308136 2/6 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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