Protein Alignment mthl5 and adgrg6

DIOPT Version :10

• Sequence 1: NP_001287291.1
• Gene: mthl5 / 41438
• FlyBaseID: FBgn0037960
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: XP_073788884.1
• Gene: adgrg6 / 561970
• ZFINID: ZDB-GENE-041014-357
• Length: 2223
• Species: Danio rerio
• Alignment Length: 298
• Identity: 64/298 - (21%)
• Similarity: 108/298 - (36%)
• Gaps: 62/298 - (20%)

  Fly   224 GISLVILLVIAIIYFILPTLSRDLVGNIVTTIAMCLMVSQAADLVRIF-----------TELTSH 277
            |||.:......:.|.....|.||....|:..::..|:.     |..:|           .||.
Zfish  1843 GISAIFSAATLLTYIAFEKLRRDYPSKILMNLSTSLLF-----LNMVFLLDGWLASYEIKELC-- 1900

  Fly   278 VSFIVADIILCFSLLAAFFW--LNSFGFYI--WKTFRSRNVFLRVTDGRKYCYYSAYAWGCTATM 338
               :...:.|.|.||.:|.|  |.|...||  .|.|   |.::|    |....:....||..||:
Zfish  1901 ---VTVAVFLHFFLLTSFTWMGLESIHMYIALVKVF---NTYIR----RYILKFCIVGWGVPATI 1955

  Fly   339 AALAVFAHFFLDAESYKQEHMVGEQETIGWLGICIFFAP----IACTILVNIFFYVTTRKLI--- 396
            .|:.:    .:..:||.:.:....::..|....|....|    :.|....:|.|.:.....|
Zfish  1956 VAIVL----AVSKDSYGKNYYGKGKDGQGTSEFCWILNPVVFYVTCVAYFSIIFLMNVAMFIVVM 2016

  Fly   397 ----------NRRTVYGRIAHKLKANFIMFSLMLLVMSIAWLFLIMSWLQME-GLLYAHIVVNAL 450
                      :.||:...|...|::   :.||..| :.:.|.|...:|..:. ..:|...:.|:|
Zfish  2017 IQICGRNGKRSNRTLREDILRNLRS---VVSLTFL-LGMTWGFAFFAWGPVSLAFMYLFTIFNSL 2077

  Fly   451 QTPLLLYI--CVLRQRHVTFLLKKTCCYNEPPSAN-DW 485
            | .|.:::  |.|::.......:..||.....:.| ||
Zfish  2078 Q-GLFIFVFHCALKENVQKQWRRYLCCGKLRLADNSDW 2114

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl5	NP_001287291.1	7tmB3_Methuselah-like	215..474	CDD:410632	59/284 (21%)
		TM helix 1	215..239	CDD:410632	4/14 (29%)
		TM helix 2	249..271	CDD:410632	3/21 (14%)
		TM helix 3	281..308	CDD:410632	10/30 (33%)
		TM helix 4	324..344	CDD:410632	5/19 (26%)
		TM helix 5	371..396	CDD:410632	5/28 (18%)
		TM helix 6	409..435	CDD:410632	6/25 (24%)
		TM helix 7	438..463	CDD:410632	7/27 (26%)
adgrg6	XP_073788884.1	None