DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl5 and Adgrg5

DIOPT Version :9

Sequence 1:NP_001287291.1 Gene:mthl5 / 41438 FlyBaseID:FBgn0037960 Length:497 Species:Drosophila melanogaster
Sequence 2:NP_001139444.1 Gene:Adgrg5 / 382045 MGIID:2685955 Length:524 Species:Mus musculus


Alignment Length:331 Identity:71/331 - (21%)
Similarity:122/331 - (36%) Gaps:107/331 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   213 LLRKILNPIF--HGISLVILLVIAIIYFI---LPTLSRDLVGNIVTTIAM--------------- 257
            |.:|:||..|  |.::|....:.::::.:   .|.||  |....:|.::.               
Mouse    52 LEQKLLNASFGGHNLTLQTNSIQSLVFKLSCDFPGLS--LSSTTLTNVSQVRAPHAMQFPAELTK 114

  Fly   258 -CLMVSQAAD--LVRIFTELTSHV------SFIVADIILCFSL-----------LAAFFWLNSF- 301
             ..:.|:.|:  |:.|:. .|:|:      |.::.:.:|...|           :...||.|.. 
Mouse   115 GACVTSRPAELRLICIYF-FTAHLFQDDRNSSLLNNYVLGAQLDHRPVNNLQKPVNISFWHNRSL 178

  Fly   302 -GFYI----WKTFRSRNVFLRVTDGRKYCYYSAYAW---GC-TATMAALAVFAH-----FF---- 348
             |:.:    ||...|::              |..||   || |...:|..|..|     :|    
Mouse   179 EGYTVSCVFWKEGASKS--------------SWGAWSPEGCYTEQPSATQVLCHCNHLTYFAVLM 229

  Fly   349 -LDAESYKQEHMVGEQETIGWLGICIFFAPIACTILVNIFFYVTTRKLINRRTVYGRIAHKLKAN 412
             |..:....|..| ..|.|.::|..|.......|||:    |..:||..:..|   ||...|..:
Mouse   230 QLSGDPVPAELQV-PLEYISFVGCSISIVASLLTILL----YAQSRKQSDSTT---RIHMNLNGS 286

  Fly   413 FIMFSLMLLVMSIAWL----------------FLIMS---WLQMEGL-LYAHI--VVNALQTPLL 455
            .::.::..|:.|...|                :.::|   |:.:||. ||..:  |.||.....|
Mouse   287 VLLLNVTFLLSSQMTLPTMPRPVCKVLAAVLHYALLSSLTWMAIEGFNLYLFLGRVYNAYIRRYL 351

  Fly   456 LYICVL 461
            |.:|:|
Mouse   352 LKLCML 357

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl5NP_001287291.1 7tm_4 212..451 CDD:304433 67/319 (21%)
Adgrg5NP_001139444.1 GPS 184..228 CDD:366827 13/57 (23%)
7tm_GPCRs 242..514 CDD:391938 31/124 (25%)
TM helix 1 244..268 CDD:341315 8/27 (30%)
TM helix 2 277..298 CDD:341315 5/23 (22%)
TM helix 3 311..333 CDD:341315 3/21 (14%)
TM helix 4 353..369 CDD:341315 2/5 (40%)
TM helix 5 405..428 CDD:341315
TM helix 6 449..474 CDD:341315
TM helix 7 478..503 CDD:341315
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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