Protein Alignment mthl5 and mthl4

DIOPT Version :9

• Sequence 1: NP_001287291.1
• Gene: mthl5 / 41438
• FlyBaseID: FBgn0037960
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_788394.1
• Gene: mthl4 / 36960
• FlyBaseID: FBgn0034219
• Length: 517
• Species: Drosophila melanogaster
• Alignment Length: 454
• Identity: 93/454 - (20%)
• Similarity: 174/454 - (38%)
• Gaps: 85/454 - (18%)

  Fly    41 VTSHVTSAGSSTALSSDPNLVLVNKCCEKFEIHVDHEC------QQVNETDYFQPMFTSYGGEQN 99
            |.|||...    |....|   .:..||.:::.....:|      .::|:.|.|..:..|.|....
  Fly    70 VASHVRGC----ACHLRP---CIRFCCPQYQKMQKSKCYGDMSEDELNKHDPFVNVTLSDGSVVR 127

  Fly   100 RPVKFKFVI--GIPNCGSMQMWPIYHYAGSSDKLVLLDDGRLRHYTNAENEAEERHGIQSDYEED 162
            |..|...::  .:...|..:|:.:.|....::..:..:...|||:...|....|
  Fly   128 RHFKEDLIVQSDLAKPGCPRMYFLNHELPGNEFTLFENGSLLRHWDKVELSKRE----------- 181

  Fly   163 IAGSLEPLYHDYDKGLYCIDKATSSTGEENVLFA-NICLARKEIK--WSDSNFLLRKILNPIFHG 224
                            ||:...  |..::::..| :.|....|..  |.....:
  Fly   182 ----------------YCVQHL--SFKDDSIRIAPHFCPLSSEHSRTWKTVAIV----------- 217

  Fly   225 ISLVILLVIAIIYFILPTLSRDLVGNIVTTIAMCLMVSQAADLVRIFTELTSHVS--FIVADIIL 287
            |||:.:::...:|..:..| |:|.|...    :|.:.|.......:...:..:.|  .:.|..:.
  Fly   218 ISLICIILTISVYLYVEKL-RNLHGKCF----ICYLASLFLGYFFLVLNVWKYSSGFCVTAGFLG 277

  Fly   288 CFSLLAAFFWLNSFGFYIWKTFR-SRNVFLRVTDGRKYCYYSAYAWGCTATMAALAVFAHFFLDA 351
            .||::||||||:..|.::...|. :.|...|:.....:..|:.||||....|.|:...|...:..
  Fly   278 YFSVMAAFFWLSVIGIHLRIKFSLASNCLHRLLPENPFRAYNLYAWGIPLIMTAITYTADQVVKN 342

  Fly   352 ESYKQEHMVGEQETI--GWLGICI-FFAPIACTILVNIFFYVTTRKLIN--RRTVYGRIAHKLKA 411
            |..:....||:...|  |.:.:.| |:.|:...|..||..:|.:...|.  ::.|.| :.||.:.
  Fly   343 EKLRPRVGVGKNCWIYTGDMTVMIYFYGPMLLLIAFNIIMFVLSAIYIYNIKKNVKG-LVHKQQT 406

  Fly   412 N--------FIMFSLMLLVMSIAWLFLIMSWLQMEGLLYAHIVV-----NALQTPLLLYICVLR 462
            |        |.:|..:.::|.::|.|.|:|:|..:...:|..::     |..|..::..:.:|:
  Fly   407 NQQINDQQMFAIFLRLFILMGLSWSFEILSFLLTKQQAWARALMVADYFNWSQGTIIFVLFILK 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl5	NP_001287291.1	7tm_4	212..451	CDD:304433	60/259 (23%)
mthl4	NP_788394.1	Methuselah_N	23..201	CDD:284145	28/166 (17%)
		7tm_4	213..>385	CDD:304433	43/187 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810