Protein Alignment mthl5 and ADGRD1

DIOPT Version :9

• Sequence 1: NP_001287291.1
• Gene: mthl5 / 41438
• FlyBaseID: FBgn0037960
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_001317426.1
• Gene: ADGRD1 / 283383
• HGNCID: 19893
• Length: 906
• Species: Homo sapiens
• Alignment Length: 376
• Identity: 79/376 - (21%)
• Similarity: 154/376 - (40%)
• Gaps: 91/376 - (24%)

  Fly   183 KATSSTGEENVLFANICLARKEIKWSD--------------------SNFLLRKILNPI------ 221
            :||:|:....|..|.:..:..|..||:                    :||.:...:.|:
Human   530 EATNSSNRVFVYCAFLDFSSGEGVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARGH 594

  Fly   222 --------FHGISLVILLVIA--IIYFILPTLS--RDLVGNIVTTIAMCLMVSQAADLVRIFTEL 274
                    :.|.||.:|.::|  :.:.:|.::|  |:...:|...::..::|:|...|:....|.
Human   595 QVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLEP 659

  Fly   275 TSHVSFIVADIILCFSLLAAFFWLNSFGFYIW----KTFRSRNVFLRVTDGRKYCYYSAYAWGCT 335
            .:....::| ::|.:..|:||.|:...|.:::    |.|.|        :..|:.||....||..
Human   660 GTTPCQVMA-VLLHYFFLSAFAWMLVEGLHLYSMVIKVFGS--------EDSKHRYYYGMGWGFP 715

  Fly   336 ATMAALAVFAHFFLDAESYKQEHMVGEQETIGWL-----GICIFFAPIACTILVNIFFYVTTRKL 395
            ..:..:::  .|.:|  ||...:..       ||     .|..|.||....|:|||...:...::
Human   716 LLICIISL--SFAMD--SYGTSNNC-------WLSLASGAIWAFVAPALFVIVVNIGILIAVTRV 769

  Fly   396 INRRT-----VYG-RIAHKLKANFIMFSLMLLVMSIAWLFLIMSWLQMEG----LLYAHIVVNAL 450
            |::.:     ::| ..|.||.|..:  :::|.::..:|:|.:   |.:.|    ..|....:|:|
Human   770 ISQISADNYKIHGDPSAFKLTAKAV--AVLLPILGTSWVFGV---LAVNGCAVVFQYMFATLNSL 829

  Fly   451 Q-TPLLLYICVLRQ------RHVTFLLKKTCCYNEPPSANDWGDELHYMNG 494
            | ..:.|:.|:|..      :|.|.:...|.......:|..:..:|  |||
Human   830 QGLFIFLFHCLLNSEVRAAFKHKTKVWSLTSSSARTSNAKPFHSDL--MNG 878

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl5	NP_001287291.1	7tm_4	212..451	CDD:304433	57/275 (21%)
ADGRD1	NP_001317426.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810