DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mthl5 and Adgrg2

DIOPT Version :9

Sequence 1:	NP_001287291.1	Gene:	mthl5 / 41438	FlyBaseID:	FBgn0037960	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_852031.1	Gene:	Adgrg2 / 266735	RGDID:	628618	Length:	1013	Species:	Rattus norvegicus

Alignment Length:	283	Identity:	54/283 - (19%)
Similarity:	111/283 - (39%)	Gaps:	33/283 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   224 GISLVILLVIAIIYFILPTLSRDLVGNIVTTIAMCLMVSQAADLVRIFTELTSHVSFIVA-DIIL 287
            |:|.:.|.|..:.|.....:.||....|:..:...|::.....|:..:..|.:...|.:: .:.|
  Rat   633 GLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYNARGFCISVAVFL 697

  Fly   288 CFSLLAAFFWLNSFGFYIW----KTFRSRNVFLRVTDGRKYCY-YSAYAWGCTATMAALAVFAHF 347
            .:.||.:|.|:....|:::    |.|   |.::     |||.. :....||..|.:.::.:
  Rat   698 HYFLLVSFTWMGLEAFHMYLALVKVF---NTYI-----RKYILKFCIVGWGIPAVVVSIVL---- 750

  Fly   348 FLDAESY----KQEHMVGEQETIGWL-GICIFFAPIA---CTI-LVNI-FFYVTTRKL--INRRT 400
            .:..::|    ..:...|..:...|: ...:|:..:.   |.| |:|: .|.|...:|  |.::.
  Rat   751 TISPDNYGIGSYGKFPNGTPDDFCWINSSVVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKK 815

  Fly   401 VYGRIAHKLKANFIMFSLMLLVMSIAWLFLIMSWLQME-GLLYAHIVVNALQ-TPLLLYICVLRQ 463
            ..|........:....:.:..::.|.|.|...:|..:. ..:|...:.|.|| ..:.::.|..::
  Rat   816 QLGAQRKTSIQDLRSIAGLTFLLGITWGFAFFAWGPVNLTFMYLFAIFNTLQGFFIFIFYCAAKE 880

  Fly   464 RHVTFLLKKTCCYNEPPSAN-DW 485
            .......:..||.....:.| ||
  Rat   881 NVRKQWRRYLCCGKLRLAENSDW 903

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mthl5	NP_001287291.1	7tm_4	212..451	CDD:304433	46/245 (19%)
Adgrg2	NP_852031.1	GPS	566..608	CDD:280071
Adgrg2	NP_852031.1	7tm_4	621..871	CDD:304433	48/249 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810