Protein Alignment mthl5 and mthl12

DIOPT Version :9

• Sequence 1: NP_001287291.1
• Gene: mthl5 / 41438
• FlyBaseID: FBgn0037960
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_731791.2
• Gene: mthl12 / 261599
• FlyBaseID: FBgn0045442
• Length: 488
• Species: Drosophila melanogaster
• Alignment Length: 473
• Identity: 90/473 - (19%)
• Similarity: 172/473 - (36%)
• Gaps: 157/473 - (33%)

  Fly    58 PNL--------VLVNKCCEKFEIHVDHECQQVNETDYFQPMFTSYGGEQNRPVKF--------KF 106
            |||        ..:..||.:..|..:.||..               |.:|. :|.        ..
  Fly    76 PNLRGCICKVRPCIRICCARKNILSNGECSD---------------GVKNE-IKLTMLDLTMQDI 124

  Fly   107 VIGIPNCGSMQMWPIYHYAGSSDKLVL--------------------LDDGRLRHYTNAENEAEE 151
            ::..|....:.|.|.|:   |::.|:|                    |.||.:..:|:||..:.:
  Fly   125 LLTDPTLAELNMIPQYN---STELLILREQFQPCDEIVSLKRDEYTILKDGSILLHTSAEILSND 186

  Fly   152 RHGIQSDYEEDIAGSLEPLYHDYDKGLYCIDKATSSTGEENVLFANICLARKEIKWSDSNFLLRK 216
            ::.:   |.|        :|.|:.:.:..|:                                |:
  Fly   187 QYCL---YPE--------IYSDFPETIRIIN--------------------------------RR 208

  Fly   217 ILNPIFHGISLVILLVIAIIYFILPT---LSRDLVGNIVTTIAMCLMVSQ-------AADLVRIF 271
            ....:..||:.  |.||:::.|||..   ||.:.:.|::....:|.:.|.       ..|..|:.
  Fly   209 CYRNVMPGIAQ--LSVISVVGFILTLAVYLSVEKLRNLLGKCLICSLFSMFMEYFIWTMDYFRLL 271

  Fly   272 TELTSHVSFIVADIILCFSLLAAFFWLNSFGFYIWKTFRSRNVFLRVTDGRKYCYYSAYAWGCTA 336
            ..:.|     .|..:..|..::::.|.:...|::|:.|.|.|   |.....::..|:.:.| |||
  Fly   272 QSICS-----AAGYMKYFFSMSSYLWFSVVSFHLWELFTSLN---RHEPQYRFLIYNTFVW-CTA 327

  Fly   337 TMAALAVFAHFFLDAESYKQ--EHMVGEQE---TIGWLGICI--------FFAPIACTIL--VNI 386
            .:..:.:|        |..|  |:..|:.|   .:|:.|..:        |::.|...||  .|:
  Fly   328 AIPTVVIF--------SMNQMWENDPGKSEWLPLVGYFGCSVKDWNSSSWFYSHIPIVILNSFNV 384

  Fly   387 FFYVTTRKLI--NRRTVYGRIAHK------LKAN---FIMFSLMLLVMSIAWLFLIMSWLQMEGL 440
            ..:|.|...|  .::.|.....|.      |:.|   :|.|..:.|:|..:||...::.|..:
  Fly   385 IMFVLTAIYIWKVKKGVKSFAQHDERNTTCLEFNVQTYIQFVRLFLIMGASWLLDQLTRLAED-- 447

  Fly   441 LYAHIVVNALQTPLLLYI 458
              :|::::.:...|.:|:
  Fly   448 --SHLLLDTIVLNLTVYL 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl5	NP_001287291.1	7tm_4	212..451	CDD:304433	59/274 (22%)
mthl12	NP_731791.2	Methuselah_N	27..209	CDD:284145	30/194 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810