Protein Alignment mthl5 and ADGRG3

DIOPT Version :9

• Sequence 1: NP_001287291.1
• Gene: mthl5 / 41438
• FlyBaseID: FBgn0037960
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: XP_005255899.1
• Gene: ADGRG3 / 222487
• HGNCID: 13728
• Length: 596
• Species: Homo sapiens
• Alignment Length: 349
• Identity: 72/349 - (20%)
• Similarity: 117/349 - (33%)
• Gaps: 97/349 - (27%)

  Fly   180 CIDKATSSTGEENVLFANICLARKEIKWSDSNFLLRKILNPIFHGISLVILLVIAIIY-FILPTL 243
            |.|..|        .||  .|.|..:..|..:.|.|  ::....|:|::.|....|:| |:.|.|
Human   245 CCDHLT--------FFA--LLLRPTLDQSTVHILTR--ISQAGCGVSMIFLAFTIILYAFLSPGL 297

  Fly   244 SR---------DL-VGNIVTTI-----------------AMCLMVS----QAADLVRIFTELTS- 276
            ..         || .|.|....                 |..|.:|    ::.|..:|...|..
Human   298 GHGPHPQQAECDLPAGRIAGPCERGLERQEKLPPAPQGGAWHLRLSRERFKSEDAPKIHVALGGS 362

  Fly   277 ----HVSFIV---------------ADIILCFSLLAAFFWLNSFGFYIW-KTFRSRNVFLRVTDG 321
                :::|:|               ...:..:.||.||.|:....|::: ...|..|.:.    |
Human   363 LFLLNLAFLVNVGSGSKGSDAACWARGAVFHYFLLCAFTWMGLEAFHLYLLAVRVFNTYF----G 423

  Fly   322 RKYCYYSAYAWGCTATMAALAVFAHFFLDAESYKQEHMVGEQETIGWLGICIF---FAPIACTIL 383
            ..:...|...||..|.|.....      .|.||.. :.:.::|....|.:|.|   ....|..|.
Human   424 HYFLKLSLVGWGLPALMVIGTG------SANSYGL-YTIRDRENRTSLELCWFREGTTMYALYIT 481

  Fly   384 VNIFFYVT-----------TRKL--INRRTVYGRIAHKLKANFIMFSLMLLVMSIAWLFLIMSWL 435
            |:.:|.:|           ..|:  ::|.|.........|....:..|..|| .:.|...|.:.|
Human   482 VHGYFLITFLFGMVVLALVVWKIFTLSRATAVKERGKNRKKVLTLLGLSSLV-GVTWGLAIFTPL 545

  Fly   436 QMEGLLYAHIVVNALQTPLLLYIC 459
            .: ..:|...:.|:||.   ::||
Human   546 GL-STVYIFALFNSLQG---VFIC 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl5	NP_001287291.1	7tm_4	212..451	CDD:304433	60/307 (20%)
ADGRG3	XP_005255899.1	GPS	213..255	CDD:280071	5/19 (26%)
		7tm_4	355..564	CDD:304433	44/224 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810