DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl5 and lat-1

DIOPT Version :9

Sequence 1:NP_001287291.1 Gene:mthl5 / 41438 FlyBaseID:FBgn0037960 Length:497 Species:Drosophila melanogaster
Sequence 2:NP_001366731.1 Gene:lat-1 / 174419 WormBaseID:WBGene00002251 Length:1014 Species:Caenorhabditis elegans


Alignment Length:325 Identity:68/325 - (20%)
Similarity:122/325 - (37%) Gaps:87/325 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   204 EIKWSDSNFLLRKILNPIFHGISLVILLVIAIIYF--ILPTLSRDL-------------VGNIVT 253
            |:||..|...|.      :|..::.......:.:|  ::.....||             ||.|::
 Worm   504 ELKWKPSGCKLS------YHNKTMTSCDCTHLTHFAVLMDVRGHDLNEIDQTLLTLLTYVGCIIS 562

  Fly   254 TIAMCLMVSQAADLV-------RIFTELTSHVSFIVADI--------------------ILCFSL 291
            .|  ||:::..|.|:       |:|......:|..:|:|                    .|.:..
 Worm   563 II--CLLLTFFAYLIFSRNGGDRVFIHENLCLSLAIAEITFLAGITRTEDSLQCGIIAVALMYMF 625

  Fly   292 LAAFFWLNSFGFYIWKTFRSRNVFLRVTDGRKYCY-YSAYAWGCTATMAALAVFAHFFLDAESY- 354
            |:|..|:...|::|.:..  ..||  .:|.|::.| ...|......|:.|      :..:::.: 
 Worm   626 LSALTWMLLEGYHIHRML--TEVF--PSDPRRFTYLLVGYIPPAIITLVA------YLYNSDGFG 680

  Fly   355 KQEH-MVGEQETIGWLGICIFFAPIACTIL-VNIFFYVTTRKLINRRTVYGRI--AHKLKA---- 411
            ..:| .:..|....|     |||..||.|. .|....|.|...:.:.|..|.:  .|.:.:    
 Worm   681 TPDHCWLSTQNNFIW-----FFAGPACFIFCANSLVLVKTLCTVYQHTSGGYLPCRHDVDSGRSI 740

  Fly   412 -NFIMFSLMLL-VMSIAWLFLIMSWLQMEG---LLYAHIVVNALQTPLLLYICVLRQRHVTFLLK 471
             |::..||.|. ::.:.|:|.:. |::...   :.|...:.|:||.   |:|.:.   ||.|..|
 Worm   741 RNWVKGSLALASLLGVTWIFGLF-WVEDSRSIVMAYVFTISNSLQG---LFIFLF---HVVFAEK 798

  Fly   472  471
             Worm   799  798

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl5NP_001287291.1 7tm_4 212..451 CDD:304433 56/295 (19%)
lat-1NP_001366731.1 Gal_Lectin 51..133 CDD:396628
HormR 180..244 CDD:214468
GAIN 258..462 CDD:406802
GPS 493..541 CDD:197639 7/42 (17%)
7tmB2_latrophilin-like_invertebrate 548..808 CDD:320556 59/275 (21%)
TM helix 1 551..575 CDD:320556 7/25 (28%)
TM helix 2 584..605 CDD:320556 4/20 (20%)
TM helix 3 615..637 CDD:320556 4/21 (19%)
TM helix 4 655..671 CDD:320556 3/15 (20%)
TM helix 5 690..713 CDD:320556 9/27 (33%)
TM helix 6 744..766 CDD:320556 6/22 (27%)
TM helix 7 771..796 CDD:320556 8/30 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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